26 citations
,
August 2014 in “Genetic Testing and Molecular Biomarkers” High levels of TNF-α may contribute to obesity and insulin resistance in PCOS, but not due to the C850T genetic variation.
22 citations
,
January 1987 in “Dermatology” Hair loss is common, influenced by genetics and androgens, and can affect mental health.
1 citations
,
August 2005 in “Springer eBooks” Alopecia areata is an autoimmune disease with genetic links, treatable with certain medications, and can affect mental health.
Genetic factors in PCOS are complex, with potential influences from the MC4R gene.
February 2025 in “PubMed” Alopecia areata cases have increased globally, affecting mostly women aged 30-34, with links to other health issues.
February 2024 in “The Open dermatology journal” Alopecia Areata affects people of all ages worldwide, is likely caused by genetic and environmental factors, and can lead to stress and depression, highlighting the need for treatments that address both physical and mental health.
January 2023 in “International Journal of Zoological Investigations” Certain genetic variations in IL-16 may increase the risk of alopecia areata.
May 2022 in “Rossijskij žurnal kožnyh i veneričeskih boleznej” Alopecia areata is complex, often recurring, and needs personalized treatment, especially with other health issues.
January 2001 in “Cambridge University Press eBooks” Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.
January 2006 in “Chinese Journal of Dermatology” Shorter GGC triplet repeats in the androgen receptor gene are linked to less hair loss in Han men.
258 citations
,
July 2016 in “Reproductive Biology and Endocrinology” The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.
50 citations
,
May 2018 in “International journal of cardiology” Testosterone is linked to cardiovascular risk factors and stroke, but its exact role is unclear.
46 citations
,
May 2020 in “Cureus” Zinc is vital for immune health, growth, and preventing diarrhea.
43 citations
,
December 2013 in “Seminars in Cell & Developmental Biology” Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.
4 citations
,
January 2022 in “Open Health” Eating healthy, exercising, and changing behaviors are the best first steps to treat Polycystic Ovary Syndrome (PCOS).
July 2023 in “Journal of Biomedical Science” Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.
Eating healthy, exercising, and certain nutrients like myoinositol and omega-3s can help manage PCOS symptoms.
May 2015 in “Journal of The American Academy of Dermatology” Treatment with biologic agents can significantly improve psoriasis symptoms, and blood biomarkers could potentially predict individual patient's response to treatment.
7 citations
,
April 2017 in “Health Economics, Policy and Law” The document suggests reevaluating the patent system to ensure public benefits from pharmaceutical privileges and to encourage more significant innovations.
88 citations
,
May 2012 in “Human Reproduction Update” Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.
22 citations
,
October 1996 in “Dermatologic clinics” Understanding intermediate filaments helps explain hair health and related diseases.
1 citations
,
January 2025 in “Frontiers in Immunology” Genetically at-risk healthy people show similar immune issues as those with Pemphigus vulgaris or Alopecia areata.
1 citations
,
October 2018 in “Journal of Mind and Medical Sciences” Switching to generic drugs is necessary but faces communication and information challenges.
244 citations
,
September 2008 in “Annual Review of Genomics and Human Genetics” The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.
69 citations
,
November 2010 in “Middle East Fertility Society Journal” PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.
49 citations
,
November 2021 in “Annual review of pathology” Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
32 citations
,
December 2018 in “Cytokine” Type I interferons play a key role in the development of various skin diseases.
28 citations
,
February 2021 in “Open Forum Infectious Diseases” African Americans faced worse COVID-19 outcomes due to a mix of social, environmental, and biological factors.
9 citations
,
December 2024 in “Clinical and Experimental Obstetrics & Gynecology” PCOS is a major cause of infertility and requires personalized treatment.
7 citations
,
March 2024 in “Skin Research and Technology” miR-200c-3p could help diagnose and treat alopecia areata.