research Gene expression profiling gets to the root of human hair follicle stem cells
Human hair follicle stem cells can be isolated using specific markers for potential therapeutic use.
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research COVID-19 and Sex Differences
Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.
research Fundamental hair follicle biology and fine fibre production in animals
Hair follicle growth and fiber production in animals are influenced by chemical signals, proteins, pigmentation, genetics, and nutrients.
research MicroRNA profiles of four induced pluripotent stem cell lines derived from distinct tissues
iPSC lines from different tissues share a common miRNA profile, supporting their pluripotent nature.
research Distinct tooth regeneration systems deploy a conserved battery of genes
Different fish use the same genes to regrow teeth.
research Safe Selection of Genetically Manipulated Human Primary Keratinocytes with Very High Growth Potential Using CD24
Researchers found a safe and effective way to pick genetically modified skin cells with high growth potential using CD24.
research Skin grafting for the treatment of chronic leg ulcers – a systematic review in evidence‐based medicine
Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.
research Alopecia Areata
Understanding the immune-related causes of Alopecia Areata has led to potential treatments like JAK inhibitors.
research Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma
Activated protein C helps protect mice from long-term radiation damage.
research Network-based identification genetic effect of SARS-CoV-2 infections to Idiopathic pulmonary fibrosis (IPF) patients
SARS-CoV-2 may worsen IPF due to shared genes and pathways, suggesting potential drug targets.
research Using WGCNA (weighted gene co-expression network analysis) to identify the hub genes of skin hair follicle development in fetus stage of Inner Mongolia cashmere goat
Researchers found WNT10A to be a key gene in developing goat hair follicles.
research Characterization of the Promoter Regions of Two Sheep Keratin-Associated Protein Genes for Hair Cortex-Specific Expression
The KRTAP11-1 gene promoter is crucial for specific expression in sheep wool cortex.
research Genetics of Wool and Cashmere Fibre: Progress, Challenges, and Future Research
More research is needed to improve wool and cashmere quality through genetics.
research Differential Expression of MITF, WNT3A, SLC7A11, and EDN3 in the Shoulder ‘Bider Marking’ of Dun Mongolian Horses
MITF and WNT3A are key in Dun Mongolian horse pigmentation.
research Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men
Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
research Alopecia Areata: a Comprehensive Review of Pathogenesis and Management
New treatments for Alopecia Areata show promise but need to be more effective and affordable.
research Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne
Genetic variations affecting skin structure play a key role in severe acne.
research A functional polymorphism in interleukin-1α (IL1A) gene is associated with risk of alopecia areata in Chinese populations
A certain genetic variation in the IL1A gene may lower the risk of a hair loss condition in Chinese people.
research Three-dimensional reconstructions of mechanosensory end organs suggest a unifying mechanism underlying dynamic, light touch
Dynamic, light touch is sensed through a common mechanism involving Piezo2 channels in sensory axons.
research Hormonal regulation of hair follicles exhibits a biological paradox
Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.
research Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity
Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
research Human Hair Follicle and Epidermal Melanocytes Exhibit Striking Differences in Their Aging Profile which Involves Catalase
Hair follicle cells age faster and lose pigment due to less catalase, causing hair to turn gray.
research The idiosyncratic genome of Korean long-tailed chicken as a valuable genetic resource
Korean long-tailed chickens have unique genes valuable for ornamental breeding.
research A comparative study of skin transcriptomes and histological observations for black and white hair colors of giant panda
The study found that giant pandas have more melanin in black hair follicles than white, with gene expression differences that could affect hair color and skin health.
research Treatment of acne vulgaris: a literature review / Lečenje običnih akni (acne vulgaris) – pregled literature
The document concludes that effective acne treatment requires a personalized combination of therapies and long-term commitment, with retinoids being important for maintenance.
research Whn and mHa3 are components of the genetic hierarchy controlling hair follicle differentiation
Whn is crucial for hair growth in certain areas by controlling a specific gene.
research Machine learning driven multi-omics analysis of the genetic mechanisms behind the double-coat fleece formation in Hetian sheep
Key genes IRF2BP2 and EGFR are linked to Hetian sheep's double-coat fleece.
research Morpho‐regulation in diverse chicken feather formation: Integrating branching modules and sex hormone‐dependent morpho‐regulatory modules
Sex hormones, especially estradiol, can change chicken feather shapes and colors.
research Defining stem cell dynamics and migration during wound healing in mouse skin epidermis
Stem cells help heal wounds by rapidly dividing and migrating to the wound edge.
research Association of Insulin Resistance with Hyperandrogenia in Women
Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.