60 citations
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March 2006 in “Journal of Medical Genetics” A mutation in the KRTHB5 gene causes hair and nail issues.
26 citations
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April 2024 in “Particle and Fibre Toxicology” Nanoplastics can penetrate skin cells, triggering inflammation and immune responses.
359 citations
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September 2017 in “European Journal of Epidemiology” The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.
31 citations
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May 2008 in “Drug Discovery Today: Disease Mechanisms” Different hair growth problems are caused by genetic issues or changes in hair growth cycles, and new treatments are being developed.
1 citations
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February 2025 in “Medicina” No significant genetic link to alopecia areata was found in the Jordanian group.
March 2026 in “Saudi Journal of Pathology and Microbiology” Personalized genomic interventions can effectively manage chronic hair loss.
480 citations
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August 2014 in “Nature Biotechnology” Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
336 citations
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August 2015 in “European Journal of Epidemiology” The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.
186 citations
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July 1998 in “Journal of Cutaneous Medicine and Surgery” Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.
175 citations
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November 2009 in “PLOS ONE” Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.
131 citations
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November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.
116 citations
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September 2001 in “Journal of The American Academy of Dermatology” Hair loss occurs due to fewer papillary cells, smaller follicles, and shorter growth phases.
115 citations
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September 2000 in “The Lancet” Early hair loss may indicate risk of insulin resistance.
112 citations
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July 2008 in “Dermatologic Therapy” Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.
84 citations
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October 2014 in “PLoS Genetics” Wnt signaling is essential for forming the skin's spinous layer through a BMP-FGF pathway.
82 citations
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March 2012 in “Development” Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
78 citations
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August 2012 in “Human molecular genetics online/Human molecular genetics” A new gene, JMJD1C, may affect testosterone levels in men.
75 citations
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June 1999 in “Pediatric Clinics of North America” The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.
65 citations
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November 2012 in “Tissue Engineering Part B-reviews” Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.
65 citations
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September 2010 in “Journal of the Neurological Sciences” Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.
63 citations
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March 2016 in “International Journal of Molecular Sciences” Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.
53 citations
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March 2014 in “Cold Spring Harbor Perspectives in Medicine” The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.
47 citations
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June 2012 in “Genes & Development” A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.
41 citations
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September 2012 in “Cellular and Molecular Life Sciences” MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.
40 citations
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October 2012 in “Dermatologic clinics” More research is needed to understand the genetic causes of Alopecia areata to develop better treatments.
40 citations
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July 2008 in “PROTEOMICS” A new model helps study acne and test treatments.
39 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
31 citations
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January 2010 in “GenomeBiology.com (London. Print)” The research concluded that selection significantly shaped the genetic variation of the X chromosome, with certain regions affected by past selective events.
29 citations
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March 2023 in “European Journal of Human Genetics” New genetic factors linked to acne risk were discovered, highlighting the role of certain pathways and genes.
29 citations
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December 2012 in “Current Opinion in Endocrinology, Diabetes and Obesity” With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.