research Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne
Spironolactone is better than placebo for reducing excessive hair growth in women, but its effectiveness for acne is unclear due to small study sizes.
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research Skin disorders in elderly subjects
Every elderly patient had at least one skin condition, often linked to other diseases, highlighting the need for integrated skin and general healthcare in the elderly.
research The Steroidogenesis Inhibitor Finasteride Reduces the Response to Both Stressful and Rewarding Stimuli
Finasteride reduces response to stress and rewards, affecting behavior and mental health.
research Finasteride and Erectile Dysfunction in Patients with Benign Prostatic Hyperplasia or Male Androgenetic Alopecia
Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.
research Skin toxicity of anti‐cancer therapy
Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.
research Adverse cutaneous reactions to chemotherapeutic agents and cytokine therapy
Chemotherapy and cytokine therapy can cause various skin reactions, including hair loss and hypersensitivity.
research Hair follicles and their role in skin health
Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
research Signs of physical abuse and neglect in the mature patient
Elderly abuse is often by family members, and doctors, especially dermatologists, can spot it by looking for unusual injuries and malnutrition.
research Sorafenib-Associated Facial Acneiform Eruption
Sorafenib can cause facial acne-like eruptions, which improve after reducing the dose or stopping the drug.
research Current concepts in aesthetic endocrinology
Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.
research Role of liposomal drug-delivery system in cosmetics
Liposomes improve the delivery and effectiveness of cosmetic ingredients but face challenges like cost and stability.
research Hair follicle characteristics as early marker of Type 2 Diabetes
Hair characteristics might be early signs of Type 2 Diabetes and could help with early prevention.
research Clinical picture of infectious syphilis
The document concludes that syphilis has varied symptoms that are often missed, making clinical awareness crucial for diagnosis.
research Nodules on the hair: A rare case of mixed piedra
A woman's scalp nodules were successfully treated with antifungal and anti-lice medications, revealing a rare case of mixed piedra infection.
research Cutaneous Manifestations in COVID-19: Report on 31 Cases from Five Countries
Some COVID-19 patients have different skin problems, which might be the only sign of the virus or related to other health issues.
research Prevalence Study of Dermatologic Manifestations among Diabetic Patients
Most diabetic patients have skin problems, which are more common with longer diabetes duration and poor blood sugar control.
research Inappropriate Sexual Behaviors in Patients with Vascular Dementia: Possible Response to Finasteride
Finasteride may help reduce inappropriate sexual behaviors in dementia patients with prostate issues.
research Men’s use of cosmetic surgery and the role of traditional masculinity ideologies
Men use cosmetic surgery to feel and look better, often influenced by traditional masculinity ideals.
research Sexual dimorphism following in vitro ischemia in the response to neurosteroids and mechanisms of injury
Male tissue has more cell death than female tissue after ischemia, and some neurosteroids only protect female cells.
research Changes in the Hydrophobic Proteins in Response to Biotin Administration in Serum of Infant Patients with Alopecia as Assessed by the Protein Micro-Sequencing Method
Biotin helps regulate proteins in the blood, which may explain its role in hair growth.
research Expression of type 1 5α-reductase and metabolism of testosterone in reconstructed human epidermis (SkinEthic®): a new model for screening skin-targeted androgen modulators
The study created a new method to test drugs that affect hormone processing in skin.
research Severe impact of late diagnosis of congenital adrenal hyperplasia on gender identity, sexual orientation and function: case report and review of the literature
Late diagnosis of congenital adrenal hyperplasia can greatly affect physical development, gender identity, and sexual health.
research Dermatologic Adverse Events from Cancer Treatments
Cancer treatments can cause skin-related side effects that may affect patient quality of life and require changes in treatment.
research Dermatology and Pregnancy
Pregnancy can cause skin changes and affect existing skin conditions, with limited treatment options due to the need for fetal safety.
research Ingestion of topical steroid triggering pustular psoriasis?
Accidentally eating a topical steroid may rarely cause acute generalized pustular psoriasis.
research Spectrum and clinical burden of Unrecognized Dermatologic Diseases in hospitalized adults: A single-centre cross-sectional study
Many skin issues in hospitalized adults go unnoticed, needing better checks and teamwork.
research Geriatric Dermatologic Therapy
Elderly skin care needs personalized treatment, early intervention, and integrated psychiatric care.
research Challenges of using tissue engineering methods in the treatment of hypospadias
The treatment of hypospadias is challenging due to the complexity of the condition and the lack of standardized surgical methods. Despite advancements in tissue engineering and cell therapies, translating laboratory findings into clinical practice is inadequate, primarily due to the absence of standardization and short clinical trial follow-ups. Tissue engineering and cell therapies, including the use of various stem cells, show promise in urethral reconstruction, but the transition from in vitro results to clinical applications is unsatisfactory. The document emphasizes the importance of selecting the right cell type, scaffold material, and injection method for successful tissue engineering. While biological scaffolds like small intestine submucosa show potential, synthetic scaffolds need further optimization. Overall, promising developments exist, but further research and standardization are needed for effective clinical applications.
research Sexual dysfunction in chronic diseases: How does technology help treat and manage sexual dysfunction in chronic patients?
Technology can improve sexual dysfunction in chronic disease patients but faces challenges like cost and accessibility.
research Zinc Spray for Treatment of Acrodermatitis Enteropathica: A Case Report
Zinc spray and cream effectively treated a baby's zinc deficiency disorder.