research Frontal fibrosing alopecia presenting with rapidly spreading facial papules in a premenopausal woman: Case report and review
A young woman developed facial bumps before hair loss, which is unusual for her condition.
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930-960 / 1000+ resultsresearch Cultured dermal papilla cells of the rat vibrissa follicle. Proliferative activity, adhesion properties and reorganization of the extracellular matrix in vitro
Rat dermal papilla cells have unique properties and interact differently with their environment compared to other skin cells.
research Cooperation of TGF ‐β and FGF signalling pathways in skin development
TGF-β and FGF pathways are crucial for skin development and regeneration.
research Comprehensive RNA sequencing in primary murine keratinocytes and fibroblasts identifies novel biomarkers and provides potential therapeutic targets for skin-related diseases
New biomarkers and potential treatments for skin diseases were identified.
research さまざまな臓器からの培養線維芽細胞による毛包誘導
Cells from skin and lung can help regenerate hair follicles.
research CXCL12 Drives Reversible Fibroimmune Remodeling in Androgenetic Alopecia Revealed by Single-Cell RNA Sequencing
Blocking CXCL12 can reverse hair loss and fibrosis in androgenetic alopecia.
research Characterization of Hair Follicle Bulge in Human Fetal Skin: The Human Fetal Bulge Is a Pool of Undifferentiated Keratinocytes
research miR-3606-3p alleviates skin fibrosis by integratively suppressing the integrin/FAK, p-AKT/p-ERK, and TGF-β signaling cascades
miR-3606-3p reduces skin fibrosis by blocking key signaling pathways.
research Deletion of an enhancer in FGF5 is associated with ectopic expression in goat hair follicles and the cashmere growth phenotype
A genetic change in the FGF5 gene affects hair growth in cashmere goats.
research Ancestral Diversity of Skin Reaches Single-Cell Resolution
Ancestry affects skin healing, with non-Hispanic Black patients showing more healing-related fibroblasts than White patients.
research Further research needed if finasteride is to become standard of care for frontal fibrosing alopecia (FFA)
More research needed to confirm finasteride as standard treatment for FFA.
research Frontal fibrosing alopecia: reflections and hypotheses on aetiology and pathogenesis
FFA's causes may include environmental triggers and genetic factors.
research LncRNA018392 promotes proliferation of Liaoning cashmere goat skin fibroblasts through up-regulation of CSF1R by binding to SPI1
A specific RNA helps increase the growth of skin cells in Liaoning cashmere goats by working with a protein to boost a growth-related gene.
research The multipotency of adult vibrissa follicle stem cells
Adult vibrissa follicle stem cells can regenerate hair follicles, glands, and skin.
research Melanocortin receptors in fibroblastic cell types of the skin –in vitro and in vivo expression and functional relevance
MC-1R is present in skin cells and may help reduce inflammation.
research Growth factors specifically alter hair follicle cell proliferation and collagenolytic activity alone or in combination
Growth factors can either promote or inhibit hair follicle cell growth and collagen breakdown.
research A rare adverse event following laser hair reduction
Laser hair reduction can sometimes cause a rare skin condition called Fox-Fordyce disease.
research Generalised Gingival Fibromatosis and Hypertrichosis: A Rare Case of Syndromic Presentation
A 16-year-old girl with gum overgrowth and excessive hair growth had successful gum surgery and healed well.
research 3D-Hautmodelle von Patienten mit Small Fiber Neuropathie
A protocol was developed to create 3D skin models from adult diseased cells to study Small Fiber Neuropathy.
research 1362 The role of Fgf20 in establishing the hair follicle dermal condensate
Fgf20 is important for the development and regulation of the cells that form the base of hair follicles.
research Telogen Phase of Hair Growth Cycle Is Regulated by Cyclic Epithelial FGF18 Signaling
FGF18 controls hair growth rest phase.
research 1378 A multi-omics approach to identifying factors involved in hair follicle growth and development
The research found that certain factors in hair follicle cells control hair growth and development, and these could be used to create new treatments for hair loss.
research Bulge cells of human hair follicles: segregation, cultivation and properties
Researchers found that bulge cells from human hair can grow quickly in culture and have properties of hair follicle stem cells, which could be useful for skin treatments.
research 742 Augmentation of HGF signaling: Potential for enhancing hair follicle neogenesis and development in bioengineered skin
Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.
research Frontal fibrosing alopecia: A multicenter review of 355 patients
Most patients with frontal fibrosing alopecia are postmenopausal women, and treatments like finasteride and dutasteride can improve or stabilize the condition.
research Four Independent Mutations in the Feline Fibroblast Growth Factor 5 Gene Determine the Long-Haired Phenotype in Domestic Cats
FGF5 gene mutations cause long hair in domestic cats.
research Frontal fibrosing alopecia: a pathology on the rise
Frontal fibrosing alopecia is increasing, especially in postmenopausal women, and treatment with finasteride can improve it.
research Development of a 3D In Vitro Model of Dupuytren’s Disease as a Platform for Drug Screening
A 3D model of Dupuytren’s disease was developed for better drug testing.
research Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes
FTase and GGTase-I are essential for skin keratinocyte health.
research Effects of platelet-rich fibrin on human endometrial stromal cells behavior in comparison to platelet-rich plasma
PRF is better than PRP for endometrial repair.