research Specific morphogenetic events in mouse external genitalia sex differentiation are responsive/dependent upon androgens and/or estrogens
Mouse genital development depends on male or female hormones for specific features.
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630-660 / 1000+ resultsresearch Common Gynecologic Problems in Prepubertal Girls
Most genital symptoms in prepubertal girls are normal or nontraumatic, not signs of abuse.
research Disorders linked to insufficient androgen action in male children
Male children's genital development issues can be caused by genetic mutations or environmental factors affecting hormone action.
research External genitalia abnormalities in male rats exposed in utero to finasteride, a 5α-reductase inhibitor
Finasteride exposure in pregnancy causes genital abnormalities in male rats.
research Vulvar Discomfort in a 10-year-old Girl
A 10-year-old girl had genital pain from a small, red, crusty mass on her labia.
research Case Report: Disorder of Sex Development 46, XY with Proximal Hypospadias in a 10-Year-Old Twin Boy: Disorder of Sex Development 46, XY with Proximal Hypospadias
A 10-year-old boy with abnormal genital development had surgery and tests to find the cause and plan treatment.
research Androgen Biosynthesis and Gene Defects
Gene mutations can cause problems in male genital development.
research Disorders linked to insufficient androgen action in male children
Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.
research Vaginal Bleeding in Pre-pubertal Females
Recurrent vaginal bleeding in young girls without puberty signs may require a genital exam to find hidden causes.
research Segmental cherry angiomas associated with extragenital lichen sclerosus: A report of two cases
Two patients had a rare combination of red skin spots and white scaly skin lesions not on the genitals.
research Reply
Dr. Rasmussen disagrees with Alexander and Schor, emphasizing uncertainty in genital wart transmission and advocating for discussions on potential abuse and referrals in such cases.
research The quality of sexual life after vaginal surgical interventions
Vaginal surgeries generally did not significantly change women's sexual quality of life.
research Podophyllotoxin-loaded solid lipid nanoparticles for epidermal targeting
P-SLN nanoparticles effectively deliver podophyllotoxin to the skin.
research Setting the Standard of Dermal Tolerance Testing for Safe and Effective Male and Female Pubic Hair Removal
The creams are safe for pubic hair removal with minor, temporary skin irritation.
research Unusual Presentation of Denys-Drash Syndrome in a Girl with Undisclosed Consumption of Biotin
A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.
research Human Osteoblast-Like Cells Express Predominantly Steroid 5α-Reductase Type 1
Human bone cells mainly produce a type 1 enzyme that may help regulate bone health.
research LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1.
LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
research Chronic prostatitis and chronic pelvic pain in men: aetiology, diagnosis and management1
Chronic pelvic pain in men is common, but its cause is unknown and treatments are often ineffective.
research Hair tourniquet syndrome
Hair tourniquet syndrome is a rare condition where hair wraps around an infant's body part, needing quick removal to prevent damage.
research [Dermatologic aspects of male hypogonadism].
Male hypogonadism affects skin and hair, causing thin skin, less hair, and skin reactions to treatment.
research Predominant expression of 5 alpha-reductase type 1 in pubic skin from normal subjects and hirsute patients.
The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.
research Gonadal Dysgenesis: Associations between Clinical Features and Sex of Rearing.
Gonadal biopsy is the best method to diagnose gonadal dysgenesis.
research Diagnostic criteria for enduring sexual dysfunction after treatment with antidepressants, finasteride and isotretinoin
The document sets criteria for diagnosing long-term sexual dysfunctions caused by certain medications.
research Transmasculine Hormone Therapy
Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.
research Platelet-Rich Plasma: A Promising Regenerative Therapy in Gynecological Disorders
Platelet-rich plasma shows promise for treating various female reproductive health issues but requires more research.
research Moth-eaten essential syphilitic alopecia
A 35-year-old man had patchy hair loss that was actually due to syphilis, not alopecia areata.
research Accessibility and Insurance Coverage for Gender-affirming Surgery in Canada: A Cross-Sectional Analysis
There is unequal access to gender-affirming surgeries in Canada, with a need for better coverage and specialized programs.
research Ketoconazole: A Promising Drug for Fungal Infections
Ketoconazole is effective for treating various fungal infections and has new uses in dermatology, but oral use can have serious side effects.
research Disorders of sex development (DSD) 46.XY due to type 2 5-α reductase deficiency in three siblings: Case report from a low-resource setting
Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.
research The laboratory in the multidisciplinary diagnosis of differences or disorders of sex development (DSD)
Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.