85 citations
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March 2008 in “Journal of Cell Science” The mutation causing Hutchinson-Gilford progeria syndrome leads to severe skin problems and early death in mice.
28 citations
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June 2012 in “International Journal of Molecular Medicine” Radiation damages hair stem cells and changes keratin expression, with Krt5 as a potential marker for radiation effects.
January 2010 in “Zhongguo xiandai yixue/Zhongguo xiandai yixue zazhi” TGF-β1 and TNF-α contribute to lung damage after radiation.
Loss of the p53 gene alone causes tumors, and losing both p53 and Rb genes speeds up aggressive skin cancer.
November 2005 in “Physiology” Apoptosis, not oxidative stress, is linked to aging in mice with mtDNA mutations.
The balance between cell renewal and differentiation controls the growth of cancerous cells in mouse skin.
28 citations
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December 2006 in “Clinical lung cancer” Early recognition and management of skin side effects from new cancer therapies can prevent treatment delays.
Inhibiting mTORC2 can reduce DNA repair and increase cancer cell death, suggesting potential for targeted brain cancer treatments.
2 citations
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March 2013 in “Phytotherapy Research” Ascorbigen increases hair cell growth in a lab setting but does not prevent hair loss from chemotherapy in mice.
August 2025 in “International Journal of Cancer” Childhood and adult height, and early immune-related hospitalizations increase testicular cancer risk, while baldness, larger families, and sports reduce it.
July 2025 in “Scientific Reports” Six key genes can predict bladder cancer outcomes and may serve as prognostic biomarkers.
35 citations
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April 1998 in “PubMed” Activated erbB-2 in mice skin causes severe skin and hair abnormalities.
November 2025 in “Free Radical Biology and Medicine” SOD1 and KL are promising targets for new hair loss treatments.
42 citations
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January 2002 in “Skin Pharmacology and Physiology” Reconstructed skin models are useful for studying how skin processes certain chemicals.
3 citations
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June 2017 in “International Journal of Radiation Biology” Gamma rays did not change hair follicle density but increased white and hypopigmented hairs in mice.
10 citations
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July 2011 in “Archives of Pharmacal Research” 17 citations
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May 2019 in “Molecules” These temporary hair dyes may be harmful to human health.
11 citations
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January 2008 in “International journal of environment and health” Children are at risk of health issues from exposure to platinum group elements from car exhausts.
19 citations
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July 2015 in “Journal of Ginseng Research” Korean Red Ginseng may protect against hair loss caused by chemotherapy.
12 citations
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May 2015 in “Molecular Medicine Reports” Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.
April 2026 in “Amino Acids” Polyamines are crucial for skin tumor development, and inhibiting them can prevent tumors.
32 citations
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December 2019 in “The Journal of clinical investigation/The journal of clinical investigation” A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.
65 citations
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February 2011 in “Molecular cancer therapeutics” CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.
278 citations
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May 2013 in “Ca” Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.
May 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Nicastrin deficiency may cause skin cell damage and pigmentation disorders in humans, similar to effects seen in fish.
13 citations
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March 2017 in “Genomics” Genomic approach finds new possible treatments for hair loss.
18 citations
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October 1986 in “PubMed” Alpha-tocopherol does not prevent hair loss from doxorubicin.
2 citations
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January 2016 in “Sarcoma” Inducing survivin in normal tissues can protect against radiation damage.
February 2024 in “Indian Journal of Chemistry” Compound N4 effectively kills breast cancer cells and compounds N2 and N3 have strong antibacterial and antifungal properties.
19 citations
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June 2001 in “Annals of Internal Medicine” Tamoxifen can cause total hair loss but its benefits outweigh this side effect.