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Oncogenic Ras Mutation Induces Spatiotemporally Specific Tissue Deformation Through Converting Fluctuated Into Sustained ERK Activation

research LB1011 Oncogenic ras mutation induces spatiotemporally specific tissue deformation through converting fluctuated into sustained ERK activation

July 2022 in “Journal of Investigative Dermatology”

A specific mutation in Kras causes abnormal tissue changes by making a cell signal continuously active, which disrupts normal cell coordination.

research Circ 0020938 inhibits hair follicle stem cells proliferation via the miR-142-5p/DSG4 axis in cashmere goats

May 2025 in “BMC Genomics”

Circ 0020938 slows down hair growth in cashmere goats.

research Breast cancer resistance protein identifies clonogenic keratinocytes in human interfollicular epidermis

14 citations , March 2015 in “Stem Cell Research & Therapy”

ABCG2 protein marks stem-like skin cells in human epidermis.

Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-Associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21

research Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21

98 citations , June 2001 in “Journal of biological chemistry/The Journal of biological chemistry”

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

research Characterization of a First Domain of Human High Glycine-Tyrosine and High Sulfur Keratin-associated Protein (KAP) Genes on Chromosome 21q22.1

100 citations , December 2002 in “Journal of biological chemistry/The Journal of biological chemistry”

Researchers mapped and categorized specific keratin-associated protein genes on human chromosome 21q22.1.

research Effect of keratin‐gelatin and bFGF‐gelatin composite film as a sandwich layer for full‐thickness skin mesh graft in experimental dogs

50 citations , December 2007 in “Journal of Biomedical Materials Research Part B Applied Biomaterials”

Keratin-gelatin films improve skin graft success in dogs.

research Bioinformatics analysis of EST segment from goat

1 citations , January 2008 in “China Journal of Bioinformatics”

Goat skin has more keratin genes, while the mammary gland has more immunity-related genes.

research Expansion of Hair Follicle Stem Cells Sticking to Isolated Sebaceous Glands to Generate in Vivo Epidermal Structures

10 citations , June 2016 in “Cell Transplantation”

Sebaceous glands can help harvest hair follicle stem cells to regenerate skin and hair.

research Angora Mouse Mutation: Altered Hair Cycle, Follicular Dystrophy, Phenotypic Maintenance of Skin Grafts, and Changes in Keratin Expression

69 citations , May 1997 in “Veterinary Pathology”

The angora mouse mutation causes long hair and hair defects due to a gene deletion.

research The sheep KAP8-2 gene, a new KAP8 family member that is absent in humans

25 citations , September 2014 in “SpringerPlus”

Sheep have a unique gene, KAP8-2, that humans don't have, which may affect wool properties.

research Characterization and expression analysis of the hair keratin associated protein KAP26.1

50 citations , July 2008 in “British Journal of Dermatology”

research Morphologic and Histologic Comparison of Hypertrophic Scar in Nude Mice, T-Cell Receptor, and Recombination Activating Gene Knockout Mice

9 citations , November 2015 in “Plastic and reconstructive surgery/PSEF CD journals”

Gene knockout mice developed scars similar to human hypertrophic scars, useful for studying scar progression.

research Identification of Pygopus 2 as a component of the ribosomal RNA transcription complex in cancer

January 2008 in “Memorial University Research Repository (Memorial University)”

Pygopus 2 helps ovarian cancer cells grow by aiding ribosomal RNA production, independent of Wnt signaling.

research 458 UVB-induced facultative pigmentation is associated with distinct DNA methylation changes

November 2025 in “Journal of Investigative Dermatology”

Tanning ability is linked to specific DNA changes in skin genes.

research Glypican-1, -4 and 6 Participate in the Hair Follicle Stem Cell Differentiation via Specific Interactions with BMP2R, Fz7 and Patched 1

October 2024 in “SPIRE - Sciences Po Institutional REpository”

research Regulatory Effects of FGF9 on Dermal Papilla Cell Proliferation in Small-Tailed Han Sheep

May 2023 in “Genes”

FGF9 helps hair follicles grow in small-tailed Han sheep by affecting cell growth and certain signaling pathways.

research 602 Sox13 is a novel marker for hair follicle development and differentiation

September 2019 in “Journal of Investigative Dermatology”

Sox13 is a new marker for early hair follicle development and differentiation.

research Expression and Cellular Localization of Keratinocyte Growth Factor and Its Receptor in Human Hyperplastic Prostate Tissue¹

4 citations , June 1998 in “The Journal of Clinical Endocrinology & Metabolism”

KGF and its receptor are found in enlarged prostate tissue and KGF strongly increases cell growth.

research Interfollicular epidermal stem-like cells for the recreation of the hair follicle epithelial compartment

14 citations , January 2021 in “Stem cell research & therapy”

Human skin cells with stem-like features can help create new hair follicles and sebaceous glands when combined with other cells.

research Selection signatures in goats reveal a novel deletion mutant underlying cashmere yield and diameter

November 2022 in “Gigascience”

A specific genetic deletion in goats affects cashmere yield and thickness.

research Canonical prolactin signaling and global mRNA expression in the skin of Holstein heifers carrying the SLICK1 allele of the prolactin receptor gene

1 citations , February 2025 in “Journal of Dairy Science”

The SLICK1 allele in Holstein heifers affects hair and immune traits without altering prolactin signaling.

research 575 Senescent atrophic epidermis retains Lrig1+ stem cells and loses Wnt signaling, a phenotype shared with CD44KO mice

2 citations , August 2016 in “Journal of Investigative Dermatology”

research Epidermal growth factor and transferrin receptor expression in human embryonic and fetal epidermal cells

10 citations , December 1990 in “Archives of Dermatological Research”

research Impact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild‐type and BK5.Akt^WT mice

8 citations , September 2013 in “Molecular carcinogenesis”

Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.

research Exploring Differentially Expressed Genes by RNA-Seq in Cashmere Goat (Capra hircus) Skin during Hair Follicle Development and Cycling

61 citations , April 2013 in “PloS one”

The study found key genes and pathways involved in cashmere goat hair growth stages.

research Expression of apoptosis-related genes in the mouse skin during the first postnatal catagen stage, focused on localization of Bnip3L and caspase-12

4 citations , June 2015 in “Connective tissue research”

The research found changes in gene expression related to cell death in mouse skin that help understand hair follicle development and skin health.

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