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Uncoupling Desmosomal Cadherin Adhesion Activates Quiescent Hair Follicle Stem Cells and Orchestrates Self-Organized Regeneration Through Outside-In Signaling

research 1422 Uncoupling desmosomal cadherin adhesion activates quiescent hair follicle stem cells and orchestrates self-organized regeneration through outside-in signaling

April 2023 in “Journal of Investigative Dermatology”

Disrupting a specific protein's function in hair follicle stem cells triggers their activation and a self-healing process.

research Biological, cellular, and molecular characteristics of an inducible transgenic skin tumor model: a review

28 citations , December 2005 in “Oncogene”

research Analysis of histological and microRNA profiles changes in rabbit skin development

7 citations , January 2020 in “Scientific Reports”

Rabbit skin analysis showed changes in hair growth and identified miRNAs that may regulate hair follicle development.

research Differential expression of type I IRS keratin genes in three breeds of sheep

January 2012 in “Zhongguo shouyi xuebao”

Sheep breeds show different keratin gene expression in the groin, linked to hair follicle density.

Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-Associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21

research Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21

98 citations , June 2001 in “Journal of biological chemistry/The Journal of biological chemistry”

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

research Genome-wide association study for cashmere traits in Inner Mongolia cashmere goat population reveals new candidate genes and haplotypes

13 citations , July 2024 in “BMC Genomics”

New genes and markers can help breed better cashmere goats.

research Glucagon-like peptide-1 receptor and proglucagon expression in mouse skin

37 citations , March 2006 in “Regulatory Peptides”

Mice skin has components that could help with hair growth and might be used for diabetes treatment.

research An in vivo method for the detection of somatic mutations at the cellular level in mice

11 citations , February 1982 in “Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis”

A new method can detect mutations in mice by observing changes in hair follicle cells.

research Targeted inactivation of integrin-linked kinase in hair follicle stem cells reveals an important modulatory role in skin repair after injury

22 citations , May 2011 in “Molecular Biology of the Cell”

Integrin-linked kinase is crucial for normal skin healing.

research Spontaneous Squamous Cell Carcinoma Induced by the Somatic Inactivation of Retinoblastoma and Trp53 Tumor Suppressors

64 citations , February 2008 in “Cancer Research”

Inactivating both p53 and Rb genes in mice speeds up aggressive skin cancer development.

research A splice variant in KRT71 is associated with curly coat phenotype of Selkirk Rex cats

40 citations , June 2013 in “Scientific Reports”

A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.

research The Simplest Protocol for Rapid and Long-Term Culture of Primary Epidermal Keratinocytes from Human and Mouse

2 citations , January 2019 in “Methods in molecular biology”

A new method helps grow skin cells from humans and mice more easily and quickly.

Skin-Permeable Liposome Improved Stability and Permeability of bFGF Against Skin of Mice With Deep Second-Degree Scald to Promote Hair Follicle Neogenesis Through Inhibition of Scar Formation

research Skin-permeable liposome improved stability and permeability of bFGF against skin of mice with deep second degree scald to promote hair follicle neogenesis through inhibition of scar formation

26 citations , September 2018 in “Colloids and Surfaces B: Biointerfaces”

A new liposome treatment helps heal deep burns on mice by improving hair regrowth and reducing scarring.

research MicroRNA-149-Mediated MAPK1/ERK2 Suppression Attenuates Hair Follicle Stem Cell Differentiation

2 citations , February 2022 in “Human Gene Therapy”

Increasing miR-149 reduces hair follicle stem cell growth and hair development by affecting certain cell growth pathways.

research Cutaneous gain-of-function mutation of LRIG3 leads to alopecia by upregulation of ERBB, PI3K/AKT, NOTCH1 signaling pathways

May 2026 in “Scientific Reports”

Overexpression of LRIG3 in skin causes hair loss.

research Molecular cloning,sequence analysis and expression of goat Edagene

January 2012 in “Journal of Northwest A & F University”

The Eda gene helps regulate the hair cycle in goats.

research LncRNA MTC enhances the proliferation of Liaoning cashmere goat skin fibroblasts by modulating GSTM1-ASK1 interaction

March 2024 in “Cytologia”

LncRNA MTC boosts growth of goat skin cells, improving cashmere quality.

Melatonin Regulates the Mitogen-Activated Protein Kinase Pathway via the CircMPP5-miR-211-MAPK3 Axis to Induce Secondary Hair Follicle Differentiation and Development in Newborn Cashmere Goat Kids

research Melatonin regulates the mitogen-activated protein kinase ( MAPK ) pathway via the circMPP5-miR-211-MAPK3 axis to induce secondary hair follicle differentiation and development in newborn Cashmere goat kids

1 citations , October 2022 in “Research Square (Research Square)”

Melatonin helps improve Cashmere goat hair quality by promoting hair follicle growth through a specific cell signaling pathway.

research Probing keratinocyte and differentiation specificity of the human K5 promoter in vitro and in transgenic mice.

79 citations , June 1993 in “Molecular and Cellular Biology”

The K5 promoter controls gene expression in skin cells, with specific DNA segments crucial for targeting and regulation.

research Whole-genome bisulfite sequencing of goat skins identifies signatures associated with hair cycling

28 citations , August 2018 in “BMC genomics”

DNA methylation changes are linked to hair growth cycles in goats.

research Platelet-rich plasma improves caspase-3 of skin graft treated with Tilapia Mozambique bio-dressing

January 2025 in “Open Veterinary Journal”

PRP with TM bio-dressing improves skin graft healing in cats.

research Targeting the Hypoxic Microenvironment in Cutaneous Chronic Graft-Versus-Host Disease through PI3Kδ Inhibition

1 citations , November 2024 in “Blood”

PI3Kδ inhibition may effectively treat cutaneous chronic graft-versus-host disease.

research Keratin Gene Expression Differences in Wool Follicles and Sequence Diversity of High Glycine-Tyrosine Keratin-Associated Proteins (Kaps) in Magra Sheep of India

9 citations , December 2018 in “Journal of Natural Fibers”

Magra sheep's wool luster is linked to specific keratin gene expression and protein variations.

Additional File 8 of Time-Course RNA-Seq Analysis Reveals Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Hair Follicle Growth Cycle in Capra Hircus

research Additional file 8 of Time-course RNA-seq analysis reveals stage-specific and melatonin-triggered gene expression patterns during the hair follicle growth cycle in Capra hircus

January 2022 in “Figshare”

Melatonin affects when and how certain genes work during the growth of goat hair follicles.

research Mrp3, a Mitogen-Regulated Protein/Proliferin Gene Expressed in Wound Healing and in Hair Follicles

19 citations , May 2001 in “Endocrinology”

Mrp3 may aid in wound healing and hair growth.

research Exploring Differentially Expressed Genes by RNA-Seq in Cashmere Goat (Capra hircus) Skin during Hair Follicle Development and Cycling

61 citations , April 2013 in “PloS one”

The study found key genes and pathways involved in cashmere goat hair growth stages.

Efficient Genome Editing Using CRISPR/Cas9 Ribonucleoprotein Approach in iPS Cells for Recessive Dystrophic Epidermolysis Bullosa

research 924 Efficient genome editing using CRISPR/Cas9 ribonucleoprotein approach in iPS cells for recessive dystrophic epidermolysis bullosa

April 2019 in “Journal of Investigative Dermatology”

Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.

Treatment of Cystathionine Beta-Synthase Deficiency in Mice Using a Minicircle-Based Naked DNA Vector

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