research PPAR‐γ signalling as a key mediator of human hair follicle physiology and pathology
PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.
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research Pharmacological Application of Growth Factors: Basic and Clinical
Growth factor treatments are increasingly used in medicine but require more research to fully understand their mechanisms.
research Analysis of Sonic Hedgehog signalling pathway gene expression in Basal Cell Carcinoma and in GLII induced systems
GLI and EGF signalling affect Basal Cell Carcinoma development and could be therapeutic targets.
research Expression of EGF,IGF-Iand IGF-IR Gene in Mink's Skin and Hair Follicles of Pelting Period
EGF, IGF-I, and IGF-IR genes are crucial for mink skin and hair growth.
research In This Issue
Phosphatidic acid may promote hair growth like minoxidil.
research Serine Biosynthesis In Human Hair Follicles By The Phosphorylated Pathway: Follicular 3-Phosphoglycerate Dehydrogenase
research 547 CDK9 Kinase Activation in Association with AFF1-SEC Initiate Epidermal Progenitor differentiation
NCSTN gene mutation causes abnormal skin cell differentiation and more inflammation, contributing to Hidradenitis Suppurativa.
research 1434 Role of fibroblast DPP4 in wound healing, scarring and regeneration
DPP4 is important for scarring and skin regeneration, and managing its activity could improve skin healing treatments.
research Analyse de la régulation du gène Hairless et identification des voies de signalisation affectées chez les mutants «bald Mill Hill».
The mutant HR bmh protein affects hair follicle formation by failing to repress vitamin D receptor activity.
research Targeting olfactory receptor OR2AT4: An innovative aptamer-based treatment for hair growth promotion
A new treatment using a DNA aptamer can promote hair growth by targeting a specific receptor.
research Human hair proteins as natural reactive oxygen species scavengers for in vitro applications
Human hair proteins, especially keratins, can protect cells from oxidative stress in lab settings.
research Characterization of the Human Hair Shaft Cuticle–Specific Keratin-Associated Protein 10 Family
KRTAP10 proteins help form the hair shaft's tough outer layer by interacting with specific hair keratins.
research KRT17 promotes endometrial cancer cell migration as well as angiogenesis by regulating HIF-1α/VEGF pathway
KRT17 may be a new target for endometrial cancer treatment because it helps cancer cells move and form new blood vessels.
research Ginsenoside Rg3 Up-regulates the Expression of Vascular Endothelial Growth Factor in Human Dermal Papilla Cells and Mouse Hair Follicles
Ginsenoside Rg3 may help hair growth by increasing a growth-related protein in hair cells.
research Synthesis of 11α-hydroxyprogesterone hartens
Researchers successfully made new compounds for hormone level tests, but one attempt led to an unexpected product, correcting a past error.
research Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing
Hydrogel scaffolds can help wounds heal better and grow hair.
research Control of Human Hair Growth by Neurotrophins: Brain-Derived Neurotrophic Factor Inhibits Hair Shaft Elongation, Induces Catagen, and Stimulates Follicular Transforming Growth Factor β2 Expression
Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.
research Crosslinking Between Trichocyte Keratins and Keratin Associated Proteins
research Gfp-Expressing Vascularization of Gelfoam® as a Rapid in Vivo Assay of Angiogenesis Stimulators and Inhibitors
The assay quickly identifies substances that increase or decrease blood vessel growth.
research Clinical and Trichoscopic Analysis of PRP Versus GFC Used for Male and Female Pattern Hair Loss
GFC improves hair quickly, while PRP offers longer-lasting benefits; using both sequentially is recommended.
research Two Different Mutations in the Same Codon of a Type II Hair Keratin (hHb6) in Patients with Monilethrix
Mutations in the hHb6 gene cause the hair disorder monilethrix.
research Thyroid Hormone Receptor Agonist Promotes Hair Growth in Mice
TDM10842, a thyroid hormone receptor activator, was found to effectively promote hair growth in mice.
research Signaling modality within gp130 receptor enhances tissue regeneration
The gp130 receptor helps in tissue regeneration and disease progression, and manipulating it could improve healing and prevent disease.
research 1339 Casein kinase 1 inhibition in keratinocytes enhances the migration of melanocyte precursors in the hair follicle via KitL/c-Kit signaling pathway
Blocking casein kinase 1 in skin cells can help melanocyte precursors move better, potentially helping with conditions like vitiligo or gray hair.
research Faculty Opinions recommendation of Enhanced effect of platelet-rich plasma containing a new carrier on hair growth.
Adding dalteparin and protamine microparticles to platelet-rich plasma can boost hair growth more than using platelet-rich plasma alone.
research GLP-1 Receptor Agonists: Beyond Their Pancreatic Effects
GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.
research BMP4 and nuclear laminC orchestrate a expression of AHF/Trichohyalin molecule, a key modulator of keratin intermediate filaments in the hair follicle
research Epidermal expression of receptor for advanced glycation end products (RAGE) is related to inflammation and apoptosis in human skin
Skin RAGE levels are linked to inflammation and cell death.
research Hematological and hepatic effects of vascular epidermal growth factor (VEGF) used to stimulate hair growth in an animal model
VEGF gel increases hair growth but may have potential toxicity.
research Growth retardation and hair loss in transgenic mice overexpressing human H-ferritin gene
Overexpressing the human H-ferritin gene in mice causes mild growth delay and temporary hair loss.