June 2024 in “Journal of Cosmetic Dermatology” Higher homocysteine levels may inhibit hair growth and are linked to androgenetic alopecia.
6 citations
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December 2019 in “Frontiers in genetics” GLI1 might protect against the start of skin cancer and is not linked to cancer severity.
2 citations
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November 1992 in “Journal of dermatology” Hair cells grown in a lab showed specific hair proteins.
6 citations
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August 2016 in “Journal of Visualized Experiments” The CUBIC protocol allows detailed 3D visualization of proteins in mouse skin biopsies.
rhKGF2 significantly promotes hair growth and follicle development.
22 citations
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August 2015 in “PloS one” Keratin from hair binds well to gold and BMP-2, useful for bone repair.
October 2024 in “SPIRE - Sciences Po Institutional REpository” 18 citations
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July 2023 in “International Journal of Molecular Sciences” KY19382 speeds up wound healing by activating a specific cell signaling pathway.
31 citations
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October 1992 in “PubMed” A mycobacterial protein shares a similar region with a human skin protein, possibly affecting skin diseases.
21 citations
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January 1995 in “Molecular Biology Reports” Scientists discovered two versions of a new human hair keratin gene.
51 citations
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September 2012 in “Biomacromolecules” Disulfide bonds make keratin in hair stronger and tougher.
24 citations
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May 2009 in “The FASEB Journal” Akt2 and SGK3 are both important for normal hair growth and development.
29 citations
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February 2001 in “Proceedings of the National Academy of Sciences” A specific DNA region controls skin cell gene expression by working with certain proteins.
60 citations
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March 2006 in “Journal of Medical Genetics” A mutation in the KRTHB5 gene causes hair and nail issues.
24 citations
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May 2019 in “PLOS genetics” Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.
119 citations
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September 2000 in “Journal of Biological Chemistry” GKLF/KLF4 and Sp1 control Keratin 19 gene activity, influencing cancer-related changes.
January 2024 in “Advanced Healthcare Materials” Using a special gel with copper and curcumin along with a scraping massage technique improved hair growth better than the common hair loss treatment, minoxidil.
Human hair keratins can be turned into useful 3D biomedical scaffolds through a freeze-thaw process.
14 citations
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July 1994 in “Journal of Investigative Dermatology” 64 citations
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March 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” GPRC5D is linked to the formation of hair, nails, and certain tongue areas.
11 citations
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September 2010 in “American Journal of Medical Genetics - Part A” A Turkish family with sparse hair and eyebrow loss has a mutation in the U2HR gene linked to Marie Unna hereditary hypotrichosis.
12 citations
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January 2014 in “Cell structure and function” Different combinations of human hair keratins affect how hair fibers form.
April 2017 in “Journal of Investigative Dermatology” Certain mutations in the KLHL24 gene cause a skin disorder by breaking down an important skin protein.
22 citations
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January 1990
245 citations
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January 1998 in “Genes & Development” Hoxc13 gene is essential for hair, nail, and papilla development.
28 citations
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August 1992 in “Differentiation” A new pair of mouse keratins, 65 kD and 48 kD, are found in specific skin areas and are linked to a unique skin differentiation type.
2 citations
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May 2020 in “Journal of the American Academy of Dermatology” Hair shaft changes may be linked to CCCA, but their role is unclear.
2 citations
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January 1993 Trichohyalin is a versatile protein involved in hair and skin structure.
The goat hair keratin gene is very similar to sheep's and is strongly expressed in goat hair follicles.