555 citations
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July 2001 in “Genes & Development” Tcf3 and Lef1 are key in deciding skin stem cell roles.
254 citations
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January 2012 in “Nature Reviews Molecular Cell Biology” Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
146 citations
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June 2012 in “PLoS ONE” Paneth cells help support stem cells and aid tissue regeneration after injury.
99 citations
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January 2014 in “Nature communications” Scientists created stem cells that can grow hair and skin.
81 citations
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December 2009 in “Journal of Dermatological Science” Fat tissue stem cells may help increase hair growth.
65 citations
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June 2020 in “Stem Cell Research & Therapy” Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
56 citations
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May 2017 in “Nature Cell Biology” Hair can regrow after certain stem cells are lost because other stem cells can take over their role.
46 citations
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August 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” Phosphatidic acid may help hair grow by affecting cell growth pathways.
43 citations
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July 2019 in “Stem Cells International” Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
26 citations
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March 2018 in “Dermatology and Therapy” EPC-CM can reduce skin aging signs by boosting the skin's defense system.
19 citations
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August 2012 in “Cell death and differentiation” Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.
18 citations
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November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
16 citations
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December 2018 in “ACS Biomaterials Science & Engineering” The new patch made of cell matrix and a polymer improves wound healing and supports blood vessel growth.
12 citations
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November 2020 in “Journal of Dermatological Science” Found microRNA differences in hair cells, suggesting potential treatment targets for hair loss.
11 citations
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September 1996 in “Neuroscience letters” Adding fetal calf serum helps Merkel cells survive and change shape.
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April 2023 in “Cureus” Stem cells could be a better treatment for hair loss by reactivating dormant hair follicles.
6 citations
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May 2018 in “Plant Cell, Tissue and Organ Culture (PCTOC)” Adding yeast extract and methyl jasmonate to Eclipta alba cell cultures increased the production of the compound wedelolactone.
4 citations
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January 2019 in “Dermatologic Therapy” Scalp basal cell carcinoma may be more aggressive and harder to treat than other types, requiring special attention and further research.
3 citations
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May 2023 in “Current Molecular Medicine” PRP is not a stem cell treatment and should not be marketed as such.
2 citations
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November 2015 in “Actas Dermo-Sifiliográficas” Epidermal stem cells show promise for future dermatology treatments due to ongoing advancements.
2 citations
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June 2012 in “Journal of Dermatological Science” The gene HDC is important for the development of hair follicles in newborn mice.
82 citations
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March 2016 in “Cell” The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.
37 citations
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July 2016 in “Current Opinion in Cell Biology” Live imaging has advanced our understanding of stem cell behavior and raised new research questions.
CD4 T cells need IFN-γ to cause hair loss in alopecia areata.
25 citations
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May 2020 in “EMBO reports” Calcium is important for stem cell function and maintenance, especially in blood and skin cells.
13 citations
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December 2024 in “Cellular and Molecular Life Sciences” Caspases do more than kill cells; they also help in cell growth and disease, and targeting them could lead to new treatments.
7 citations
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September 2020 in “Frontiers in Cell and Developmental Biology” IL-36α helps grow new hair follicles and speeds up wound healing.
2 citations
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September 2022 in “Cellular and molecular biology” Agaricus bisporus derived β-Glucan could be an effective cervical cancer treatment with antimicrobial and antioxidant properties.
2 citations
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August 2018 in “Korean Journal of Plant Resources” Oregonin from Alnus japonica may help prevent hair loss and promote hair growth.
1 citations
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November 2025 in “Cell Death and Disease” Understanding how mesenchymal stem cells stay undifferentiated can improve their use in treating diseases.