Fibroblast Growth Factors (FGFs) help maintain and repair skin tissues, which is important for preventing diseases like inflammation, fibrosis, and cancer.
225 citations
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April 2018 in “Journal of Investigative Dermatology” Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.
October 2024 in “Consilium Medicum” Understanding fibroblasts helps improve cosmetic treatments for aging skin.
January 2026 in “Open MIND” Fibroblasts play a key role in hair loss by affecting hair growth and causing inflammation.
299 citations
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January 2018 in “Journal of Clinical Investigation” Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
418 citations
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January 2018 in “Journal of Investigative Dermatology” Researchers found four distinct fibroblast types in human skin, which could help in treating wounds and fibrotic diseases.
42 citations
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August 2008 in “Stem Cells and Development” Hair follicle cells can help regenerate teeth.
September 2021 in “Morphologia” Dermal fibroblasts have at least three distinct types, each with unique roles in skin structure and hair development.
1 citations
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August 2023 in “The Journal of Pathology” Different types of skin fibroblasts have unique roles in skin health and disease.
August 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Different types of skin cells create unique support structures that can affect skin cell growth and could help in skin repair.
3 citations
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August 2024 Deep skin fibroblasts help recruit immune cells for better wound healing.
March 2024 in “Frontiers in genetics” Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.
19 citations
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November 2012 in “Cell Communication and Signaling” FGF-9 speeds up the early development of certain organs, showing potential for organ regeneration.
11 citations
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August 2019 in “Journal of Molecular Histology” NFIC helps rat dental cells grow and turn into bone-like cells.
26 citations
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April 2012 in “PubMed” Myofibroblasts in rat wound healing may come from blood vessel pericytes and perifollicular dermal sheath cells.
37 citations
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May 2021 in “Frontiers in Cell and Developmental Biology” Ng2+ perivascular cells in mouse skin come from specific fibroblast types and help in tissue repair.
October 2022 in “Regenerative Biomaterials” A special gel with stem cells can create new hair follicles.
April 2018 in “Journal of Investigative Dermatology” Differentiated fibroblasts regenerate hair follicles better than undifferentiated ones.
42 citations
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September 2015 in “Gene” FGF5s can block the effects of FGF5, which may help control hair growth in cashmere goats.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Androgens increase growth factors in skin cells, which may lead to acne.
115 citations
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December 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.
4 citations
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December 2017 in “International Journal of Biomedicine” Fibroblast transplantation improves wound healing, with dermal equivalents slightly enhancing skin regeneration.
119 citations
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November 2014 in “Trends in Cell Biology” Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.
58 citations
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September 2022 in “Cold Spring Harbor Perspectives in Biology” Different fibroblast types play key roles in wound healing and could lead to better treatments.
15 citations
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May 2003 in “The Laryngoscope” FGF-1 causes spiral ganglion neurites to branch more.
January 2014 in “Institutional Repositories DataBase (IRDB)” Fibroblast spheres can form stem cells, but marker distribution needs more study.
17 citations
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September 2020 in “Inflammation and Regeneration” WNT activation in scalp fibroblasts boosts hair growth by increasing FGF9.
Some fibroblast growth factors may promote hair growth similarly to minoxidil and could potentially treat hair loss.
1235 citations
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December 2013 in “Nature” Two fibroblast types shape skin structure and repair differently.
126 citations
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August 2018 in “Molecular Systems Biology” Fibroblast state switching is crucial for skin healing and development.