48 citations
,
January 2003 Endophytes from Southeast Asia and Japan can produce useful substances like enzymes and antibiotics.
January 2011 in “Reactions Weekly” St. John's Wort may reduce the effectiveness of finasteride by increasing its breakdown in the body.
14 citations
,
October 2020 in “Journal of ethnopharmacology” Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.
21 citations
,
October 1978 in “The Journal of Clinical Pharmacology” 6 citations
,
March 2022 in “Molecules” Methyl jasmonate boosts tanshinone production in Salvia miltiorrhiza callus cultures.
17 citations
,
February 2018 in “Journal of Investigative Dermatology” PPAR-γ signaling improves mitochondrial function in hair follicles, potentially affecting hair growth and aging.
January 2025 in “Journal of Ethnopharmacology” Dahuang-Gancao Decoction improves hair growth in androgenetic alopecia.
4 citations
,
April 1986 in “Cancer Letters” GSH-T levels in hair follicles are similar in smokers and non-smokers and don't increase with certain treatments.
Enzymatic synthesis improved the water solubility of the flavonoid baicalin, which may help treat hair loss conditions.
August 2025 in “ACS Omega” New compounds show promise as nonsteroidal treatments for hair loss.
19 citations
,
July 2005 in “Steroids” Testosterone increases 3α-androstanediol levels, which can be blocked by finasteride.
1 citations
,
July 2025 in “Functional Foods in Health and Disease” CL22209, an Asparagus racemosus extract, safely reduces perimenopausal symptoms and balances hormones.
The S-2 herbal extract significantly promotes hair growth.
26 citations
,
November 2002 in “Planta medica” Extracts from Cercidiphyllum japonicum wood can stimulate mouse hair cell growth like common hair growth treatments.
1 citations
,
January 2025 in “Frontiers in Pharmacology” Total glucosides of paeony can help treat skin conditions but need more research for clinical use.
5 citations
,
April 2022 in “Evidence-based Complementary and Alternative Medicine” Shaoyao Gancao decoction may treat alopecia areata by affecting the PI3K/AKT signaling pathway.
February 2026 in “Journal of Dermatological Treatment” CG2001 is safe and well-tolerated for treating hair loss, with fewer side effects than oral finasteride.
May 2022 in “Endocrine Abstracts” Finasteride may cause sexual dysfunction by reducing epinephrine levels.
13 citations
,
July 2008 in “Biomedical Chromatography” The methods accurately measured brain androgens, showing most 5α-androstane-3α,17β-diol comes from outside the brain, while androsterone is both transported and made in the brain.
January 2008 in “Journal of Medicinal Chemistry” Finasteride may cause sexual and psychological side effects by affecting an enzyme related to epinephrine.
January 2026 in “Scientific Reports” Sesamin may help treat hair loss by affecting specific cell pathways.
August 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair growth supplements do not reduce the effectiveness of the breast cancer treatment tamoxifen.
17 citations
,
March 2020 in “Frontiers in Chemistry” Compounds from the plant Mammea siamensis may help treat hair loss.
57 citations
,
May 1986 in “Clinics in endocrinology and metabolism” Androstanediol glucuronide is a reliable marker for hirsutism in women.
17 citations
,
August 2007 in “Bioorganic & Medicinal Chemistry Letters” A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.
36 citations
,
June 2019 in “eLife” The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.
3 citations
,
January 1992 in “Gynecological Endocrinology” 3α, 17β-androstanediol-glucuronide is not a useful marker for androgen excess but may help monitor certain treatments.
12 citations
,
October 2004 in “Experimental Gerontology” Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.
January 2009 in “Yaowu fenxi zazhi” The method accurately and reliably detects residual solvents in Finasteride.
59 citations
,
February 1998 in “Chemico-Biological Interactions” Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.