8 citations
,
July 2016 in “Oncotarget” Lgr5+ stem cells do not cause skin tumors.
June 2009 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Lrig1 marks a unique group of stem cells in mouse skin that can become different skin cell types.
February 2022 in “Research Square (Research Square)” LGR5 is a marker found in hair follicle stem cells in various species and is important for hair growth and skin repair.
37 citations
,
January 2009 in “The Journal of Dermatology” Hair follicle stem cells can turn into various cell types and help repair nerves.
3 citations
,
July 2022 in “Stem Cell Research & Therapy” Turning off a specific gene in stem cells speeds up skin healing by helping cells move better.
419 citations
,
March 2005 in “Proceedings of the National Academy of Sciences” Hair-follicle stem cells can become neurons.
7 citations
,
February 2023 in “Inflammation and Regeneration” The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.
326 citations
,
February 2009 in “The American journal of pathology” Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.
September 2013 in “Experimental Dermatology” The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
421 citations
,
September 2003 in “Development” Stem cell behavior varies with stimuli, and lineage changes can happen without affecting stem cell division.
80 citations
,
May 2011 in “Nature Cell Biology” New methods have greatly improved our understanding of stem cell behavior and roles in the body.
15 citations
,
August 2013 in “Stem Cells and Development” The method increases stem-like cells for better skin regeneration.
1 citations
,
January 2024 in “Advances in Engineering Technology Research” Bone marrow stem cells from Guizhou miniature pigs can grow well and become different cell types, useful for tissue engineering.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing Lrig1-positive stem cells in mice causes temporary loss of sebaceous glands.
33 citations
,
September 2008 in “Biochemical and Biophysical Research Communications” Hair follicles can be used to easily create neurons and glial cells for potential nerve repair.
144 citations
,
June 2008 in “Cell Cycle” Hair follicle stem cells can help repair spinal cord injuries and improve walking.
16 citations
,
July 2008 in “BMC Genomics” Alpha 6 + /MHCI - cells have stem cell traits and are similar to mouse hair follicle stem cells.
36 citations
,
September 2013 in “PLoS ONE” Sweat gland stem cells help maintain glands, aid wound healing, and can regenerate skin structures.
37 citations
,
July 2016 in “Current Opinion in Cell Biology” Live imaging has advanced our understanding of stem cell behavior and raised new research questions.
January 2014 in “eScholarship (California Digital Library)” Lrig1 and Lgr6 stem cells help maintain hair follicles and influence skin cancer development.
IL-1 and IL-7 help activate cells that boost hair follicle stem cell growth, aiding wound healing.
8 citations
,
March 2024 in “Regenerative Therapy” Delivering IGF-1 with PLGA microspheres improves stem cell regeneration for tissues.
IL-1 signaling is crucial for hair follicle stem cell growth and wound healing.
6 citations
,
July 2013 in “Molecular Imaging” The technique allowed noninvasive tracking of hair stem cell survival and growth, showing potential for hair loss research.
10 citations
,
January 2013 in “Stem Cells and Development” Scientists identified a unique type of human skin stem cell that could help with tissue repair.
80 citations
,
September 2007 in “Cell Cycle” Stem cells in hair follicles can become various cell types, including neurons.
32 citations
,
January 2014 in “Cells tissues organs” Hair follicle stem cells can help repair nerve and spinal cord injuries.
4 citations
,
February 2023 in “Stem Cell Research & Therapy” Mouse skin cells can become sperm-like cells in the lab.
January 2014 in “Institutional Repositories DataBase (IRDB)” Fibroblast spheres can form stem cells, but marker distribution needs more study.
91 citations
,
June 2011 in “The EMBO Journal” TCF/Lef1 activity is essential for proper skin cell development and renewal.