research Successful management of severe alopecia areata and vitiligo using topical delgocitinib and a 308-nm excimer laser
Combining topical delgocitinib with a 308-nm excimer laser can effectively treat severe alopecia areata and vitiligo.
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780-810 / 1000+ results research EMULGEL EMERGENT SYSTEMS: AT A GLANCE FOR TOPICAL DRUG DELIVERY
Emulgels are effective for delivering skin medications and cosmetics due to their easy application and controlled release.
research In vitro antibacterial evaluation of aqueous and methanol extracts of Tridax procumbens flower on selected pathogenic organisms
Tridax procumbens flower extracts can kill bacteria.
research Antimalarial therapy for granuloma annulare: Results of a retrospective analysis
Antimalarial drugs, especially chloroquine, can effectively treat granuloma annulare.
research Aldesleukin
Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.
research Hair graying and loss induced by imatinib mesylate
A woman's hair turned gray and fell out after starting a cancer drug called imatinib mesylate.
research A Case of Valproate Toxicity Related to Isoniazid
Valproic acid and isoniazid can interact, causing toxicity, so careful monitoring is needed.
research Role of GABA-active neurosteroids in the efficacy of metyrapone against cocaine addiction
Neurosteroids may help metyrapone reduce cocaine addiction.
research MON-369 Treatment of Nonclassic 11-Hydroxylase Deficiency with "Hair, Skin, and Nails," an Over-the-Counter, Insulin Sensitizing Vitamin/Mineral Supplement
An over-the-counter vitamin/mineral supplement improved hair loss and blood sugar control in a woman with non-classic 11-hydroxylase deficiency.
research Molecular and physiological mechanisms underlying the antifungal and nutrient acquisition activities of beneficial microbes
Certain beneficial microbes can fight fungi and help plants get nutrients.
research Investigation of the mechanisms of progesterone protection following oxygen–glucose deprivation in organotypic hippocampal slice cultures
Progesterone protects brain cells by converting to allopregnanolone and involving GABAA receptors.
research Adverse events of dual anti-seizure medication: Real-life data from a tertiary epilepsy clinic
Dual anti-seizure medications, especially valproic acid with lamotrigine, often cause more side effects like hair loss and memory issues.
research Evaluation of Biological Activity Exerted by an Aza-bicyclocarboxylic acid Derivative using Anischemia-Reperfusion Injury Model
Compound 3 protects the heart from damage by activating A1-adenosine receptors.
research Cyanoacrylate glue as an effective skin-decontamination method for hair follicle microbiome sampling: insights from a nonhuman model (Capreolus capreolus)
This study investigates the use of cyanoacrylate glue (CAG) as a skin-decontamination method for sampling the hair follicle microbiome, using roe deer as a nonhuman model. The research highlights the challenge of contamination from skin surface microbes during biopsy. Results show that CAG significantly reduces microbial contamination in biopsy samples, decreasing bacterial and fungal presence by 3.7-fold compared to untreated samples. The study suggests that CAG is an effective decontamination step, providing valuable insights for future human hair follicle microbiome research.
research Tapinarof cream for atopic dermatitis: Pharmacokinetics, systemic exposure, and preliminary efficacy/safety results
Tapinarof cream at 1% concentration is effective and better tolerated for treating atopic dermatitis than the 2% concentration.
research Oral Combination Treatment of Gefitinib (IressaTM) and Sasam-Kyeongokgo: Synergistic Effects on the NCI-H520 Tumor Cell Line
Gefitinib and Sasam-Kyeongokgo together significantly reduce cancer growth and improve immune response in mice.
research Effects of Transcutol P and Precirol ATO-5 on Percutaneous Absorption of Flutamide from Emulgels
Flutamide emulgel with 1% Transcutol P absorbs better through the skin than other mixtures.
research TRIAMCINOLONE ACETONIDE INTRAMUSCULARLY: EFFECTIVE LONG‐ACTING STEROID THERAPY IN DERMATOLOGIC DISORDERS
Triamcinolone acetonide injections effectively treat skin disorders like eczema and psoriasis.
research Rapid and Sensitive LC–MS–MS Method for the Simultaneous Estimation of Alfuzosin and Dutasteride in Human Plasma
A fast and accurate method was developed to measure alfuzosin and dutasteride in human plasma.
research Anticonvulsant hypocalcaemia.
Long-term use of seizure medications can disrupt calcium metabolism, but this can be treated with vitamin D or UV light and does not affect seizure control.
research Enzyme Inhibitors from Gorgonians and Soft Corals
Marine compounds from gorgonians and soft corals show promise for drug development, especially for chronic disorders.
research AnnoPharma: Detection of substances responsible of ADR by annotating and extracting information from MEDLINE abstracts
AnnoPharma effectively identifies substances causing adverse drug reactions in medical abstracts.
research Allogeneic Hair Transplantation with Enhanced Survival by Anti-ICAM-1 Antibody with Short-Term Rapamycin Treatment in Nonhuman Primates
Using an anti-ICAM-1 antibody with rapamycin improves hair transplant survival in monkeys.
research Systemic Absorption and Pharmacokinetics of Five Novel Topical Dermatologic Agents: A Review
These new skin treatments are safer and more effective with minimal side effects.
research Carbobenzoxy-capped Phe-Lys(BODIPY TMR-X-acyloxymethyl ketone(QSY7)
Near-infrared probes can safely and effectively image cysteine protease activity for disease diagnosis.
research Back cover
A new treatment using special microneedles and a nitric oxide-releasing drug could improve hair growth and be more convenient for people with hair loss.
research Testosterone (T) secreting tumor or insulin resistance? metformin (M) as a diagnostic (Dx) and therapeutic (Rx) trial
Metformin can help diagnose and treat high testosterone levels in women, often due to insulin resistance rather than a tumor.
research First-in-human phase 1 study of ETC-159 an oral PORCN inhbitor in patients with advanced solid tumours.
ETC-159 was safe up to 30 mg, but no tumor shrinkage was seen.
research The effects of finasteride (FIN) and thioacetamide (TAA) on acetylcholinesterase (AchE) activity in various brain regions.
research Contribuição ao estudo farmacognóstico da mutamba (Guazuma ulmifolia - Sterculiaceae)
Mutamba may help treat hair loss due to its tannins and other compounds.