July 2025 in “Journal of Investigative Dermatology” Spironolactone can safely lower blood pressure in patients on other blood pressure medications, but may slightly increase the risk of low blood pressure.
Spironolactone with an oral contraceptive improved hair growth in women with hirsutism.
December 2011 in “The Diabetes Educator” The Blood Glucose Management Service improved patient safety and outcomes in managing blood sugar in hospitalized patients.
February 2024 in “Practical Diabetes” Spironolactone helps reduce hospital visits and death from heart issues, lowers blood pressure, but has unclear effects on heart failure with normal heart pump function and can cause high potassium and breast enlargement in men.
November 2024 in “Circulation” GLP1-RAs may have higher reports of suicide and hair loss, but no strong evidence links them to these issues.
February 2023 in “Reactions Weekly” January 2011 in “Clinical Cosmetic and Investigational Dermatology” Spironolactone is a safe and effective hair loss treatment, especially with minoxidil.
February 2026 in “JAAD International” 2 citations
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May 2020 in “Molecules” A new, efficient method was developed to synthesize a specific compound and its derivatives.
September 2022 in “Journal of The American Academy of Dermatology” Monitoring potassium levels is important for women taking spironolactone.
January 1993 in “Проблемы Эндокринологии” Spironolactone effectively reduces symptoms of hyperandrogenism but has some side effects.
89 citations
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November 2014 in “International Journal of Nanomedicine” Using nanostructured lipid carriers to deliver spironolactone could improve treatment for hair loss.
October 2025 in “International Journal of Dermatology” GLP-1 receptor agonists may cause hair loss, but regrowth is rare.
8 citations
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August 2020 in “Clinical and Experimental Dermatology” Spironolactone is a low-cost, effective, and generally safe treatment for various skin conditions related to hormones.
April 2021 in “Journal of Investigative Dermatology” Spironolactone safely and effectively treats hair loss in female scarring alopecia patients.
15 citations
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April 2020 in “Journal of The American Academy of Dermatology” Spironolactone effectively treats female pattern hair loss with few side effects.
December 2020 in “Forum Dermatologicum” Intralesional triamcinolone acetonide can effectively limit the progression of GLPLS.
Ganoderma lucidum extract may help treat stress-related hair loss.
October 2025 in “EMJ Dermatology” GLP-1RA therapy may increase the risk of hair loss.
September 2022 in “Journal of The American Academy of Dermatology” Dermatologists should monitor potassium levels in women taking spironolactone for acne, hair loss, and hirsutism.
January 2026 in “Frontiers in Pharmacology” Wedelolactone may help treat inflammation, infections, cancer, bone loss, and organ damage.
59 citations
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August 2021 in “Frontiers in Endocrinology” GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.
12 citations
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May 2005 in “Journal of the American Geriatrics Society” Stopping valproate and using lactulose can quickly treat valproate-induced hyperammonemia.
12 citations
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October 2022 in “Facial Plastic Surgery” Polycaprolactone gel is effective and safe for treating nasolabial folds.
28 citations
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November 2009 in “European Journal of Neuroscience” Progesterone and allopregnanolone increase glycine release in rat brain cells.
54 citations
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December 2007 in “Best Practice & Research Clinical Endocrinology & Metabolism” Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.
4 citations
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March 2024 in “Journal of the American Academy of Dermatology” Spironolactone for skin issues rarely causes low blood pressure.
May 2024 in “International Journal of Dermatology” More research is needed to understand if GLP-1 agonists affect hair health.
October 2024 in “International Journal For Multidisciplinary Research” Wedelolactone may help treat chronic diseases due to its strong antioxidant properties.
5 citations
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September 2015 in “Medical hypotheses” Topical sulfonylurea may reduce excessive hair growth caused by certain medications.