May 2023 in “Metabolites” Myo-inositol plus α-lactalbumin works better than myo-inositol alone for improving symptoms of PCOS.
Women with Polycystic Ovary Syndrome (PCOS) have a higher risk of developing type 2 diabetes due to insulin resistance.
November 2025 in “BMC Endocrine Disorders” The TT/DHT ratio may help identify PCOS patients with severe metabolic issues.
January 2025 in “PROTEOMICS” Drug repositioning is a promising way to quickly develop new treatments, especially for rare diseases.
May 2023 in “Journal of Cosmetic Dermatology” Androgenetic alopecia is linked to higher cardiovascular and metabolic risks, possibly due to irisin resistance.
October 2022 in “Biomedicines” Finasteride in male rats causes liver and metabolic issues in their offspring.
November 2025 in “Clinical and Translational Allergy” The consensus provides guidelines for safely stopping danazol in hereditary angioedema treatment.
August 2025 in “International Journal of Molecular Sciences” Osmanthus fragrans var. aurantiacus Makino may help treat inflammation due to its antioxidative and anti-inflammatory properties.
222 citations
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August 2014 in “Cell Metabolism” Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.
21 citations
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October 2022 in “International Journal of Molecular Sciences” Quercitrin may help treat Alzheimer's by boosting brain cell signaling without causing tumors.
3 citations
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October 2024 in “International Journal of Molecular Sciences” CRET therapy affects inflammation in skin cells by changing cytokine levels and activating certain proteins.
1 citations
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September 2024 in “Journal of Clinical & Translational Endocrinology” PCOS women have more severe metabolic issues and higher androgen levels than hyperandrogenic women without PCOS.
1 citations
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February 2024 in “Preprints.org” Ginsenoside compound K shows promise for treating metabolic diseases like obesity and diabetes, but more research is needed on its safety and effectiveness.
Lhx2 is essential for effective Sonic Hedgehog signaling in early retinal development.
15 citations
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January 2020 in “ILAR Journal” Nonhuman primates are valuable in research but their natural health variations can complicate study results.
112 citations
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July 2020 in “BMC Medicine” Women with PCOS may be at higher risk for severe COVID-19.
3 citations
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May 2023 in “Biomedicines” PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.
February 2025 in “Clinical Cosmetic and Investigational Dermatology” Certain blood metabolites are linked to female pattern hair loss, with some increasing risk and others offering protection.
505 citations
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October 2011 in “Journal of clinical oncology” MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.
475 citations
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October 2006 in “Proceedings of the National Academy of Sciences” Folliculin helps regulate energy and nutrient sensing, impacting Birt–Hogg–Dubé syndrome.
380 citations
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February 2023 in “Journal of Clinical Medicine” PCOS is influenced by various factors and may be managed by restoring gut health and using new therapies.
317 citations
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April 2018 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.
228 citations
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June 2021 in “Frontiers in Immunology” Macrophage issues cause chronic wound inflammation, but therapies can help.
227 citations
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April 2020 in “Cell” More precise, personalized therapies are needed for autoimmune diseases.
219 citations
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January 2006 in “Drug Metabolism Reviews” DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
175 citations
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January 2020 in “European Journal of Endocrinology” Test thyroid function in all obese patients and prioritize weight loss for hormonal balance.
138 citations
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August 2020 in “Frontiers in Endocrinology” PCOS affects health and quality of life, with effective treatments available and a need for more research on alternative therapies.
131 citations
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September 2017 in “Molecular and Cellular Endocrinology” The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
122 citations
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August 2020 in “Tropical Diseases Travel Medicine and Vaccines” COVID-19 severely affects older adults with chronic heart, lung, or metabolic diseases.
119 citations
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June 2021 in “Heliyon” Licorice has many health benefits but should be used carefully due to possible side effects.