59 citations
,
June 2023 in “Nature Aging” Blocking IL-17 signaling may reduce skin inflammation and delay aging.
51 citations
,
September 2020 in “Cell Metabolism” Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
48 citations
,
May 2015 in “NPJ microgravity” A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.
47 citations
,
March 2016 in “Journal of dermatology” Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.
47 citations
,
June 1996 in “International Journal of Legal Medicine” Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.
44 citations
,
January 2005 in “Dermatology” Hair problems can be caused by genetics or the environment, and treatment should focus on the cause and reducing hair damage.
42 citations
,
December 2016 in “Cell Death & Differentiation” Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.
41 citations
,
July 2015 in “Current Drug Discovery Technologies” Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.
40 citations
,
July 2015 in “Journal of Cellular Biochemistry” Cysteine helps maintain keratin production in skin cells even when iron is low.
40 citations
,
November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” S100A3 protein is crucial for hair shaft formation in mice.
40 citations
,
January 2016 in “PLoS ONE” Shorter daylight increases hair growth in Cashmere goats.
39 citations
,
September 2016 in “Expert Opinion on Drug Delivery” New drug delivery methods can make natural compounds more effective and stable.
39 citations
,
September 2013 in “Journal of Cosmetic Dermatology” Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.
39 citations
,
March 2008 in “Journal of biological chemistry/The Journal of biological chemistry” GLI2 increases follistatin production in human skin cells.
38 citations
,
July 2021 in “ACS Nano” Microneedles help treat hair loss by improving hair surroundings and promoting growth.
34 citations
,
September 2020 in “BMC Endocrine Disorders” Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
34 citations
,
December 2009 in “The International Journal of Developmental Biology” Too much thymosin beta4 causes weird teeth and more hair growth in mice.
31 citations
,
January 2007 in “Journal of biological chemistry/The Journal of biological chemistry” Stress activates a special function of the Vitamin D receptor with the help of c-Jun, which can also prevent cell death.
27 citations
,
March 2024 in “Frontiers in Pharmacology” Natural products can help overcome cancer drug resistance.
26 citations
,
May 2021 in “International Journal of Molecular Sciences” Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.
26 citations
,
October 2017 in “Scientific reports” A special microbe helps plants absorb rock phosphate by growing on their root hairs.
23 citations
,
January 2014 in “International Journal of Biological Sciences” African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.
23 citations
,
January 2012 in “International Food Research Journal” Tofacitinib effectively treated a woman's severe symptoms from a rare autoimmune condition.
22 citations
,
December 2016 in “PloS one” A specific protein in chicken embryos links early skin layers to feather development.
22 citations
,
October 2012 in “Journal of Investigative Dermatology” Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.
20 citations
,
January 2003 in “Journal of oleo science” Chemical treatments and daily stresses damage hair, especially the cuticle layer.
18 citations
,
February 2022 in “Cell Death Discovery” ECM1-modified stem cells can effectively treat liver cirrhosis.
15 citations
,
March 2012 in “International journal of nanomedicine” Local injections of nanosized rhEPO can speed up skin healing and improve quality after deep second-degree burns.
15 citations
,
January 1987 in “Electrophoresis” Human head hair proteins can be typed into eight distinct patterns, useful for genetic and forensic investigations.
14 citations
,
December 2016 in “Sexual Medicine” Finasteride side effects in young men may be linked to specific gene variations.