research Retinoic-Acid-Related Orphan Receptor Alpha Is Involved in the Regulation of the Cytoskeleton of Hair Follicle Stem Cells
RORA affects hair follicle stem cells' structure and movement, potentially helping treat hair loss.
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510-540 / 1000+ results research Levonorgestrel effects on serum androgens, sex hormone–binding globulin levels, hair shaft diameter, and sexual function
research Research gaps in medical treatment of transgender/nonbinary people
More research is needed on the health effects of hormone therapy for transgender and nonbinary people.
research Cardiovascular Risk Associated With Gender Affirming Hormone Therapy in Transgender Population
Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.
research Efficacy of metformin therapy in adolescent girls with androgen excess: relation to sex hormone–binding globulin and androgen receptor polymorphisms
Metformin works better for adolescent girls with PCOS who have certain genetic variations.
research Understanding key symptoms, side effects, and impacts of HR+/HER2- advanced breast cancer: qualitative study findings
Patients with HR+/HER2- advanced breast cancer commonly experience fatigue, hair loss, and pain, which significantly affect daily activities.
research A systematic review of health-related quality of life outcomes in patients with advanced breast cancer treated with palbociclib
Palbociclib generally maintains or improves quality of life in advanced breast cancer patients.
research A Review of the Most Common Dermatologic Conditions and their Debilitating Psychosocial Impacts
Common skin conditions can greatly affect a person's mental health and social life.
research Quantitative analysis of 34 sex (pro)hormones, conjugates and bioactive oxidation products thereof in human plasma by GC- and LC-MS/MS and systematic investigation of overestimations of analyte concentrations not accounted for by method validation
The method accurately measures sex hormones in human plasma but can have small errors.
research Update on polycystic ovary syndrome
The 2018 guideline for PCOS suggests new diagnostic criteria and treatments, but recognizes the need for more research.
research Short communication: Temporal changes in the skin morphology of dairy cows during the periparturient period
Dairy cows' skin and hair follicles change size and growth phase around the time they give birth.
research Hormonal Treatment of Transgender Women with Oral Estradiol
Oral estradiol works for many transgender women but needs personalized dosing and monitoring.
research Long-Term Experience With 5-alpha-Reductase Inhibitors.
Finasteride reduces prostate size and symptoms with few side effects.
research Medications Mostly Associated With Ejaculatory Disorders: Assessment of the Eudra-Vigilance and Food and Drug Administration Pharmacovigilance Databases Entries
Certain medications, especially Paroxetine, Tamsulosin, and Finasteride, are linked to ejaculatory disorders.
research Role of serum androgens and prostate-specific antigen levels in men with androgenetic alopecia
Higher testosterone and DHT levels are linked to hair loss in men, but not to prostate cancer risk.
research Risk assessment of the top 60 drugs for drug-related sexual dysfunction: a disproportion analysis from the Food and Drug Administration adverse event reporting system
Finasteride, dutasteride, and silodosin have the highest risk for causing sexual dysfunction.
research An Open Randomized Comparative Study of an Oral Contraceptive Containing Ethinyl Estradiol and Cyproterone Acetate with and without the GnRH Analogue Goserelin in the Long-Term Treatment of Hirsutism
The oral contraceptive alone is the preferred treatment for hirsutism, as adding the GnRH analog showed no significant benefit.
research Efficacy of low-dose GnRH analogue (Buserelin) in the treatment of hirsutism
Low-dose Buserelin effectively reduces hirsutism with minimal side effects.
research Management of Transgenderism
Transgender treatment includes hormones and surgery, but long-term effects are unknown and counseling is needed.
research Physiology of the Hypothalamic Pituitary Gonadal Axis in the Male
The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.
research Polycystic ovary syndrome and impact on health
PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.
research Kisspeptin and LH pulsatile temporal coupling in PCOS patients
Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.
research Polycystic ovary syndrome (PCOS)
The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.
research Effects of Prenatal Treatment with Antiandrogens on Luteinizing Hormone Secretion and Sex Steroid Concentrations in Adult Spotted Hyenas, Crocuta crocuta1
Prenatal antiandrogen treatment altered hormone levels in adult spotted hyenas, affecting males and females differently.
research Interventions for hirsutism (excluding laser and photoepilation therapy alone)
Some medicines can reduce excessive hair growth in women, but more research is needed to compare treatments and consider side effects.
research Interventions for hirsutism excluding laser and photoepilation therapy alone: abridged Cochrane systematic review includingGRADE assessments
Some medications can reduce excessive hair growth in women, but more research is needed to find the best treatment combinations.
research The hyperandrogenic-insulin-resistant acanthosis nigricans syndrome: therapeutic response
Most patients improved with oral contraceptives, but some needed additional treatment.
research Effect of the gonadotrophin releasing hormone analogue, goserelin, and oestradiol replacement on sebum excretion rates and hair size in mildly hirsute women
Goserelin and oestradiol treatment slightly improved hairiness but did not significantly change sebum production or hair characteristics in mildly hirsute women.
research Androgens
Male hormones and their interactions are crucial for male sexual development and characteristics.
research Microglia: sculptors of the polycystic ovary syndrome (PCOS)-like brain?
Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.