30 citations
,
January 2015 in “BioMed Research International” Continuous light exposure in rats leads to PCOS-like symptoms and suggests sleep habits might affect the disorder's development.
29 citations
,
April 2004 in “Annals of Pharmacotherapy” Finasteride reduces hirsutism effectively with fewer side effects but is a second-choice treatment due to safety concerns.
22 citations
,
January 2006 in “International Journal of Andrology” Taking oral testosterone with finasteride or dutasteride doubles testosterone levels, and food slightly affects it.
11 citations
,
April 2018 in “Nutrition Research” Chromium supplements don't help with weight loss or improve hormone and metabolism issues in people with polycystic ovary syndrome.
2 citations
,
November 2018 in “International journal of gynaecology and obstetrics” Women with different PCOS types have similar fertility treatment results.
1 citations
,
May 2025 in “The Journal of Phytopharmacology” Phytoandrogens from plants may help treat low testosterone naturally.
September 2024 in “Brazilian Journal of Case Reports” Clomiphene testing can help find ovarian causes of high testosterone in postmenopausal women.
February 2024 in “Journal of Health Science and Medical Therapy” ADAM17 could be a potential target for treating PCOS.
August 2016 in “Journal of Investigative Dermatology” The research found that certain microRNAs are important for human hair growth and health.
August 2016 in “Journal of Investigative Dermatology” DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.
August 2016 in “Journal of Investigative Dermatology” Researchers found a new genetic mutation linked to a hair condition in a Japanese boy.
February 2016 in “Evidence Based Women Health Journal (Online)” Women with PCOS had higher SRAGE levels, possibly linked to BMI, not PCOS.
October 2007 in “Clinical Biochemistry” New genotype linked to non-classical congenital adrenal hyperplasia found in Italian siblings.
343 citations
,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
195 citations
,
November 2019 in “Clinica Chimica Acta” High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.
49 citations
,
July 2021 in “Nutrients” Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.
18 citations
,
January 2001 in “Annual Reports in Medicinal Chemistry” Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.
17 citations
,
January 2015 in “MedChemComm” New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.
15 citations
,
June 2020 in “Experimental Dermatology” Hormones and genes affect hair growth and male baldness.
6 citations
,
February 2021 in “Journal of Ovarian Research” 150 kHz electromagnetic radiation might help improve PCOS in rats.
4 citations
,
October 2013 in “Springer eBooks” Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.
2 citations
,
February 2021 in “Brain Research” Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.
January 2026 in “Frontiers in Pharmacology” Certain drugs can cause male infertility, so fertility counseling and sperm preservation are advised.
December 2025 in “Open Repository of the University of Porto (University of Porto)” Pharmacists play a crucial role in improving patient outcomes through personalized care and staying updated with scientific advancements.
May 2024 in “Scientific Reports” Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.
December 2023 in “Research in pharmacy” Phytotherapeutic compounds and supplements can help manage Polycystic Ovarian Syndrome (PCOS).
January 2017 in “Elsevier eBooks” Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.
4809 citations
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January 2004 in “Fertility and Sterility” The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.
4025 citations
,
December 2003 in “Human Reproduction” The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.
222 citations
,
January 2014 in “International journal of reproductive medicine” Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.