1 citations
,
March 2011 in “Infertility” Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.
2 citations
,
March 2017 in “The Australian and New Zealand journal of obstetrics and gynaecology” We need better information on how fathers' exposures affect pregnancy.
104 citations
,
June 2020 in “Journal of Endocrinology” Hyperandrogenism and insulin resistance in PCOS-like rats can lead to pregnancy complications due to increased cell death in the uterus and placenta.
1 citations
,
October 2017 in “Elsevier eBooks” Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.
Finasteride reduces DHT levels and affects gene expression in fish, similar to its effects in humans.
January 2025 in “Haematology International Journal” These ovarian conditions cause high testosterone levels.
January 2026 in “Brazilian Journal of Development” Early diagnosis and surgery can improve symptoms of ovarian hyperthecosis in postmenopausal women.
April 2024 in “JCEM case reports” A man's breast enlargement from low-dose finasteride for hair loss didn't go away, even with treatment, and might be more common than reported.
19 citations
,
March 2021 in “Experimental and Therapeutic Medicine” Isotretinoin can cause serious birth defects and needs careful use, especially in pregnant women.
7 citations
,
January 2013 in “Hormone Research in Paediatrics” Ectopic adrenal rests can cause androgen excess after adrenalectomy and may need targeted surgery.
3 citations
,
July 2014 in “Indian Journal of Surgery” Sex hormones might influence bladder cancer development, and aromatase inhibitors could increase risk in postmenopausal women.
8 citations
,
July 2017 in “The Journal of Steroid Biochemistry and Molecular Biology” DHT affects testicular development and regulates spermatogenesis in some fish.
5 citations
,
January 2017 in “Endocrinology” Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.
1 citations
,
March 2005 in “Zentralblatt für Gynäkologie” A postmenopausal woman had high testosterone from her right adrenal gland, leading to recommended surgery.
September 2021 in “Fertility and sterility” Taking 100 mg of DHEA daily for 16 weeks did not change metabolic and reproductive health significantly but increased certain ovarian markers with minimal side effects.
1 citations
,
December 2024 in “Bulletin of Osh State University” Mercury can disrupt sex hormones and cause reproductive issues.
4 citations
,
August 2024 in “PLoS ONE” Both injectable contraceptives lower testosterone and SHBG levels, with NET-EN having a greater effect than DMPA-IM.
Finasteride and testosterone are the drugs most linked to male infertility, but many other potential drugs may be under-reported.
October 2024 in “Journal of the Endocrine Society” The case highlights the complexity of diagnosing high testosterone in older women and the need for thorough testing.
November 2017 in “Reactions Weekly” Testosterone undecanoate caused hair loss; finasteride improved it but caused stomach issues for one patient.
November 2007 in “Neuro-chirurgie/Neurochirurgie” Cyproterone acetate is a safe treatment that causes mild feminizing effects and is more effective with added estrogens.
October 2025 in “Journal of the Endocrine Society” A rare pituitary tumor in an 18-year-old male caused hormonal issues and vision loss, requiring surgery and further treatment.
15 citations
,
June 1986 in “Pediatric Dermatology” Androgens increase pigmentation in young hamsters, but estrogens can reverse this effect.
January 2026 in “International Journal of Innovative Technologies in Social Science” Isotretinoin effectively treats severe acne but can cause various side effects, with the most serious being birth defects, requiring careful monitoring and contraception.
February 2026 in “European Urology”
5 citations
,
October 2013 in “Endocrine” Blood tests can detect ovarian Leydig cell tumors when scans don't, and surgery can confirm and treat these tumors.
October 2022 in “Springer eBooks” The document concludes that personalized hormonal treatments are important for transgender individuals and more research is needed for non-binary treatments.
2 citations
,
November 2019 in “Case reports in women's health” Ovarian vein sampling helped diagnose rare ovarian tumors causing high testosterone, and surgery to remove the tumors lowered the testosterone levels.
January 2017 in “University journal of surgery and surgical specialities” Steroid cell tumors in ovaries are rare, can cause hormone changes, and may be cancerous.
May 2007 in “The Journal of Urology” Finasteride lowers PSA levels in men, certain factors increase testicular cancer risk, and current guidelines for penile cancer may lead to unnecessary surgeries.