research Dysregulation of Grainyhead-like 3 expression causes widespread developmental defects
Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.
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30 / 1000+ results research Gain‐of‐function variants in the ODC1 gene cause a syndromic neurodevelopmental disorder associated with macrocephaly, alopecia, dysmorphic features, and neuroimaging abnormalities
ODC1 gene mutations cause a neurodevelopmental disorder with large head size, hair loss, and facial abnormalities.
research Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes
A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.
research Mandibulofacial dysostosis with alopecia results from ETAR gain-of-function mutations via allosteric effects on ligand binding
Specific mutations in a receptor cause facial abnormalities and hair loss.
research Grading of hirsutism: a practical approach to the modified Ferriman-Gallwey scoring system
Checking the chin, thighs, upper lip, or lower abdomen is enough to predict hirsutism.
research Effect of Body Weight Gain During Cashmere Non-Growing Period on Cashmere Production Performance and Secondary Hair Follicle Activity of Cashmere Goats
Gaining 5-10 kg during the non-growing period boosts cashmere yield and length in goats.
research 889 Trpv3 gain-of-function mutation impairs differentiation of hair follicle inner root sheath
A specific mutation in the TRPV3 gene causes hair follicle cells to develop improperly, leading to hair loss.
research GainmoreTM M: An oral supplementation in men with Androgenic Alopecia for reduction in hair loss & new hair growth
Using body measurements can help achieve good results in plastic surgery like reshaping the torso, but it doesn't work for all body types.
research Weight Gain and Hair Loss during Anti-TNF Therapy
Anti-TNF therapy can cause weight gain and hair loss, leading some patients to stop treatment.
research Gleason grading controversies: what the chemoprevention trials have taught us
Finasteride reduces prostate cancer risk by 30% without affecting Gleason scores.
research A semiquantitative grading scale for frontal and vertex of androgenetic alopecia
New grading scale accurately measures hair loss severity and treatment effectiveness.
research JAK1 gain-of-function variant causes alopecia areata, atopic dermatitis, and autoimmune thyroid disease
A JAK1 variant causes hair loss, skin issues, and thyroid disease, but treatment with a specific inhibitor can help.
research Severity grading of dermatological emergencies based on comorbidities and systemic involvement: An observational study
Skin emergency severity rises with other health issues and affects multiple organs; a new grading system can improve patient care.
research Cutaneous gain-of-function mutation of LRIG3 leads to alopecia by upregulation of ERBB, PI3K/AKT, NOTCH1 signaling pathways
Overexpression of LRIG3 in skin causes hair loss.
research An overview of incidence and mechanisms promoting weight gain as an adverse effect of oral minoxidil therapy for androgenetic alopecia
Oral minoxidil for hair loss can cause weight gain due to fluid retention.
research Weight Gain - Marathon Runner/Triathlete
Over-training and under-eating caused weight gain, resolved by increasing calories and adjusting exercise.
research Weight Gain - Marathon Runner/Triathlete
Over-training and under-eating caused weight gain, resolved by increasing calories and adjusting exercise.
research A clinico-trichoscopic analysis of hair density and diameter variability in relation to severity grading of female pattern hair loss
Trichoscopic measurements help determine the severity of female pattern hair loss.
research Acne severity and the Global Acne Grading System in polycystic ovary syndrome
Acne severity in women with PCOS is linked to younger age, lower body weight, and more body hair, but not to hormone levels.
research Biological significance of FoxN1 gain-of-function mutations during T and B lymphopoiesis in juvenile mice
FoxN1 overexpression in young mice harms immune cell and skin development.
research Quantitative Studies on Human Hair Growth(II). Correlation between Subjective Grading and Objective Measurements of Hair Growth.
The study concluded that certain hair growth measurements are good indicators of baldness severity and provide a more accurate assessment than subjective grading.
research S4240 Nutrafol's Hair Gains and Liver Strains
Nutrafol may cause liver damage.
research Prediction of gain-of-function and loss-of-function mutations using Combined Annotation Dependent Depletion (CADD)
C-scores can help predict gain-of-function and loss-of-function mutations.
research Skin Semiology and Grading Scales
The document concludes that dermatology training and grading scales need to better represent dark-skinned individuals to improve diagnosis and assessment of skin conditions.
research Hoxc13 polyglycine repeat gain-of-function drives mammalian integument evolution by altering targeted genes and interactions
The polyG fragment in Hoxc13 protein helps evolve mammalian skin and hair by enhancing gene interactions.
research Limitations of Treatment-Induced Alopecia Grading Instruments in Evaluating Therapeutic Response
Current methods for grading hair loss from cancer treatment are not accurate enough and need improvement.
research Development of a New Grading Scale for Evaluating Overall Hair Density
A new reliable scale improves accuracy in measuring hair density and treatment response.
research PIK3CA gain-of-function mutation in Schwann cells leads to severe neuropathy and aerobic glycolysis through a non-cell autonomous effect
A PIK3CA mutation in Schwann cells causes severe nerve damage and increased glycolysis, but early treatment can help.
research Diagnostic and grading criteria for androgenetic alopecia using dermoscopy
New dermoscopic criteria accurately diagnose and grade the severity of hair loss in androgenetic alopecia.
research Occipital donor area grading and profile in Indian population
The conclusion is that a safe donor area for hair transplants varies and should be chosen based on individual factors like race, future hair loss, family history, and specific thinning patterns.