October 2021 in “Journal of Investigative Dermatology” Skin cell strength decreases significantly as we age.
2 citations
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April 2019 in “Experimental Dermatology” Hair follicles respond differently to pulling forces in various regions.
September 2019 in “Journal of Investigative Dermatology” Retinol significantly reduces neck wrinkles.
July 2023 in “Research Square (Research Square)” Skin's uneven surface and hair follicles affect its stress and strain but don't change its overall strength, and help prevent the skin from peeling apart.
March 2024 in “Intisari Sains Medis” PRP injections improve periorbital wrinkles and show promise as a treatment.
1 citations
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January 2025 in “International Journal of Cosmetic Science” Age-related hair curvature increases due to internal structural changes from grooming.
3 citations
,
May 2011 in “Facial plastic surgery clinics of North America” Laser treatments can effectively reduce fine wrinkles and improve skin texture.
5 citations
,
September 2013 in “BMB Reports” BMPR1a-ECD reduces wrinkles much more effectively than retinoic acid.
26 citations
,
June 1993 in “Archives of Otolaryngology - Head and Neck Surgery” The new laser technique effectively reduces forehead lines with fewer side effects and faster recovery.
April 2015 in “Experimental Dermatology” Melanoma risk tools need improvement, certain gene mutations cause skin diseases and could be treated by targeting those mutations, skin wrinkling may relate to lung aging due to genetic factors, and oxidative stress affects hair loss but can be reduced in low oxygen.
12 citations
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January 2016 in “Skin appendage disorders” Repeated botulinum toxin injections for forehead wrinkles may cause hairline recession in some women.
June 2023 in “British journal of dermatology/British journal of dermatology, Supplement” Tight hairstyles can cause a rare scalp condition with thick skin folds.
5 citations
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May 2021 in “BMC surgery” A man's unusual scalp folds caused by a skin condition were treated with surgery and remained unchanged two years later.
3 citations
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June 2017 in “Aesthetic plastic surgery” The new facial treatment improved wrinkles and skin thickness, with most patients seeing results within a month, despite some temporary swelling and bruising.
3 citations
,
July 2022 in “Dermatologic Therapy” Magnesium microneedle patches can safely improve under-eye wrinkles when used every other night for 12 weeks.
July 2019 in “Dermatologic Surgery” July 2020 in “RePub (Erasmus University, Rotterdam)” Facial skin aging is influenced by wrinkles, spots, genetics, and environment.
18 citations
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August 2017 in “PLOS ONE” Skin and its underlying fat layer act together to resist mechanical stress, and reinforcing this composite structure may help more with anti-aging than just strengthening the skin alone.
5 citations
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July 2022 in “Frontiers in Medicine” Combining microneedle-delivered ECM and radiofrequency improves skin elasticity and thickness more than ECM alone.
5 citations
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April 2013 in “Journal of Cosmetic and Laser Therapy” Argireline significantly reduces wrinkles.
1 citations
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November 2020 in “Dermatologic Surgery” Using combined hair restoration methods can effectively treat severe scalp wrinkling.
79 citations
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January 1999 in “Dermatologic surgery” Different skin treatments work best for different levels of wrinkles and sun damage.
July 2025 in “Journal of Medical Science And clinical Research” A 21-year-old male has a rare scalp condition with excessive skin folds.
3 citations
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February 2025 in “Journal of PHYSIOLOGICAL ANTHROPOLOGY” Certain genes are linked to skin aging, like wrinkles and pigmentation changes.
7 citations
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November 2017 in “Cureus” Ear creases might indicate heart disease risk, needing more research.
67 citations
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December 2009 in “International Journal of Dermatology” Hormonal changes in skin may cause stretch marks.
June 1996 in “Journal of Dermatological Science” Vitamin D3 applied to mouse skin caused more wrinkles and sagging due to changes in the skin's outer layer.
February 2026 in “Journal of Cosmetic Dermatology” Polynucleotide injections improved eye wrinkles with few side effects.
66 citations
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June 1997 in “The Laryngoscope” Tailored treatments for aging brows and foreheads improve results.
3 citations
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March 2007 in “Otolaryngologic Clinics of North America” Choosing the right eyebrow and forehead rejuvenation technique depends on the individual's features and goals, and even small changes can make a big difference in appearance.