research Nail Changes Associated With Thyroid Disease
Certain nail conditions can suggest thyroid problems, with different symptoms for underactive (slow, thin nails) and overactive (spoon-shaped, brittle nails) thyroid.
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research Menopause and hair loss in women: Exploring the hormonal transition
Menopause can cause hair loss in women due to hormonal changes, affecting their well-being and quality of life.
research Pediatric adrenocortical carcinoma complicated by uric acid nephrolithiasis: a unique case report
Thorough evaluations and conservative management can lead to positive outcomes in pediatric adrenocortical carcinoma.
research Fucoidan treatment reverses hair loss and inhibits inflammatory responses in a mouse model of androgenetic alopecia
Fucoidan may help regrow hair and reduce inflammation in hair loss.
research Porphyria Cutanea Tarda – a Case Report
Stopping oral contraceptives improved symptoms of porphyria cutanea tarda in a young woman.
research Psychosis as a late manifestation of Sheehan’s syndrome
Sheehan's syndrome can sometimes cause psychosis.
research Alopecia and hair repigmentation associated with anti-programmed death-ligand 1 (PD-L1) immunotherapy
This document reports a case of a woman in her sixties with metastatic squamous cell carcinoma who experienced alopecia areata (AA) and global hair repigmentation as immune-related adverse events (irAEs) during anti-PD-L1 immunotherapy. The patient developed AA 15 months after starting combination immunotherapy, which is later than the typical onset. She was treated with intralesional triamcinolone, resulting in full hair regrowth and unexpected generalized hair repigmentation, returning to her original hair color without external dyes. This case highlights the rare occurrence of simultaneous AA and hair repigmentation as irAEs, suggesting a disruption of hair follicle immune privilege due to PD-L1 blockade. The study emphasizes the importance of recognizing and managing irAEs to maintain patients on immunotherapy, noting that intralesional steroids can effectively restore hair growth and improve quality of life.
research Virilizing adrenocortical oncocytoma in a toddler
A toddler with a rare adrenal gland tumor causing male-like physical changes was successfully treated with surgery.
research Female pattern hair loss: current treatment concepts.
Minoxidil 2% and 5% are common treatments for female pattern hair loss, with other options including anti-androgens, oral contraceptives, and hair transplantation.
research Vitamin D and skin diseases: A review
Vitamin D is important for skin health and can help treat psoriasis, atopic dermatitis, and vitiligo.
research MEX3A regulates Lgr5 + stem cell maintenance in the developing intestinal epithelium
MEX3A is crucial for maintaining intestinal stem cells in mice.
research Androgens/Androgen Receptor in the Management of Skin Diseases
Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.
research Understanding the Secular Decline in Testosterone: Mechanisms, Consequences, and Clinical Perspectives
Lifestyle changes and environmental strategies can help address declining testosterone levels.
research Evaluation and Treatment of Hirsutism in Premenopausal Women: An Endocrine Society Clinical Practice Guideline
Treat significant hirsutism with medication and hair removal; use birth control pills first, adding antiandrogens if needed.
research The roles of activins in repair processes of the skin and the brain
Activin A helps heal skin wounds and protects the brain after injury.
research Testosterone in COVID-19: An Adversary Bane or Comrade Boon
Testosterone's effects on COVID-19 are unclear and need more research.
research Alopecia types, current and future treatment
Current alopecia treatments manage symptoms but don't cure, and better treatments are needed.
research The Impact of Nutrition on Hashimoto Thyroiditis Patients: An Overview
Proper nutrition is vital for managing Hashimoto's thyroiditis symptoms.
research Therapeutic potential of adult platelets and cord blood platelets in future clinical directions
Cord blood platelets may have promising future medical uses but need more research.
research European Society of Endocrinology Clinical Practice Guideline: Endocrine work-up in obesity
Test thyroid function in all obese patients and prioritize weight loss for hormonal balance.
research Extra-Intestinal Manifestation of Celiac Disease in Children
Early diagnosis and a strict gluten-free diet are crucial for children with celiac disease to improve symptoms.
research The Role of Nutrition on Thyroid Function
A balanced diet with essential micronutrients is crucial for healthy thyroid function.
research Natural Sources of Therapeutic Agents Used in Skin Conditions
Bee venom, fig, and geranium oil can effectively treat skin conditions and are safer alternatives to some conventional drugs.
research Narrative review of facial gender surgery: approaches and techniques for the frontal sinus and upper third of the face
Facial gender surgery techniques focus on forehead and hairline changes for accurate results.
research Approach to the Patient: Diagnostic Challenges in the Work Up for Polycystic Ovary Syndrome
Diagnosing PCOS is challenging due to its complex and varied symptoms.
research Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury
Sebaceous glands can regenerate after injury using stem cells from hair follicles.
research The Role of Nutrition in Immune-Mediated, Inflammatory Skin Disease: A Narrative Review
Diet can influence inflammatory skin diseases.
research The therapeutic, diagnostic, and prognostic values of extracellular vesicles (exosomes) in dermatology: A systematic review
Extracellular vesicles show potential in dermatology, but more research is needed for validation.
research Exploring the efficacy of testosterone undecanoate in male children with 5α‐reductase deficiency
Testosterone undecanoate safely and effectively increased penis size in male children with 5-alpha-reductase deficiency.
research Dysregulated behaviour of hair follicle stem cells triggers alopecia and provides potential therapeutic targets
Misbehaving hair follicle stem cells can cause hair loss and offer new treatment options.