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Virtual Insights into Natural Compounds as Potential 5α-Reductase Type II Inhibitors: A Structure-Based Screening and Molecular Dynamics Simulation Study

research Virtual Insights into Natural Compounds as Potential 5α-Reductase Type II Inhibitors: A Structure-Based Screening and Molecular Dynamics Simulation Study

November 2023 in “Life”

Eriocitrin and silymarin might be effective for hair loss treatment and need more research.

research Examining the Effect of Notocactus ottonis Cold Vacuum Isolated Plant Cell Extract on Hair Growth in C57BL/6 Mice Using a Combination of Physiological and OMICS Analyses

February 2023 in “Molecules”

Cactus extract from Notocactus ottonis may help promote hair growth.

Discovery of Autoantigens in the Hair Loss Disorder Alopecia Areata: Implications of Posttranslational Modifications

research Entdeckung von Autoantigenen bei der Haarverluststörung Alopecia areata: Implikation von posttranslationalen Modifikationen

January 2023 in “Karger Kompass. Dermatologie”

Scientists are still unsure what triggers the immune system to attack hair follicles in Alopecia areata.

LGR5 Is a Conserved Marker of Hair Follicle Stem Cells in Multiple Species and Is Present Early and Throughout Follicle Morphogenesis

research LGR5 is a conserved marker of hair follicle stem cells in multiple species and is present early and throughout follicle morphogenesis

8 citations , June 2022 in “Scientific Reports”

LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.

research ISHRS Best Practices Survey Project MODULE: Who Does What SUMMARY ANALYSIS

July 2015 in “International Society of Hair Restoration Surgery”

Human Gene Correlation Analysis: A Tool for the Identification of Transcriptionally Co-Expressed Genes

research Human gene correlation analysis (HGCA): A tool for the identification of transcriptionally co-expressed genes

24 citations , June 2012 in “BMC Research Notes”

The HGCA tool helps identify genes that work together by analyzing their co-expression patterns.

research Case Report: PTCH1 splice-site mutation and sonidegib treatment in Gorlin-Goltz syndrome: clinical insights from a family case study

February 2026 in “Frontiers in Medicine”

Personalized sonidegib dosing can effectively treat Gorlin-Goltz syndrome with fewer side effects.

research Brg1 Governs a Positive Feedback Circuit in the Hair Follicle for Tissue Regeneration and Repair

52 citations , April 2013 in “Developmental Cell”

Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.

research Modern trends in the variability of the mechanisms of formation and principles of diagnosis – Ganser syndrome

May 2024 in “International journal of medicine and psychology.”

Ganser syndrome may result from both organic and psychogenic factors.

AGD1, A Class 1 ARF-GAP, Acts in Common Signaling Pathways with Phosphoinositide Metabolism and the Actin Cytoskeleton in Controlling Arabidopsis Root Hair Polarity

research AGD1, a class 1 ARF‐GAP, acts in common signaling pathways with phosphoinositide metabolism and the actin cytoskeleton in controlling Arabidopsis root hair polarity

56 citations , December 2011 in “The Plant Journal”

AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.

Graft Quality Index: A Morphologic Classification of Follicular Unit Excision Grafts

research Graft Quality Index: A Morphologic Classification of Follicular Unit Excision (FUE) Grafts

6 citations , March 2018 in “Hair transplant forum international”

The Graft Quality Index grades hair transplant grafts to predict placement difficulty and surgery results.

research Progesterone regulates corticosterone elevation and alterations in spatial memory and exploratory behavior induced by stress in Wistar rats

5 citations , June 2010 in “Universitas Psychologica”

Progesterone helps protect against stress-related memory and behavior issues in rats.

research Agouti and Agouti-related Protein: Analogies and Contrasts

135 citations , March 2000 in “Journal of Biological Chemistry”

Agouti and AGRP affect pigmentation and obesity, with implications for metabolic disorders.

research GRHL3 binding and enhancers rearrange as epidermal keratinocytes transition between functional states

38 citations , April 2017 in “PLOS Genetics”

GRHL3 is important for controlling gene activity in skin cells during different stages of their development.

research Transcriptome-based selection and validation of optimal house-keeping genes for skin research in goats (Capra hircus)

23 citations , July 2020 in “BMC Genomics”

NCBP3, SDHA, and PTPRA are the best genes for accurate goat skin research.

research The Peach RGF/GLV Signaling Peptide pCTG134 Is Involved in a Regulatory Circuit That Sustains Auxin and Ethylene Actions

9 citations , October 2017 in “Frontiers in plant science”

The peach gene CTG134 helps control the interaction between auxin and ethylene, which could lead to new agricultural chemicals.

research Study on the skin structure, hair follicle cycle, and GSDMA protein expression in Ganxi goats

1 citations , September 2025 in “Frontiers in Veterinary Science”

Ganxi goats' skin and hair adapt to heat and humidity, possibly aided by GSDMA protein.

research Primary Generalized Glucocorticoid Resistance and Hypersensitivity

48 citations , January 2011 in “Hormone Research in Paediatrics”

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

research Phenotypic, transcriptomic, and genomic analyses reveal the spatiotemporal patterns and associated genes of coarse hair density in goats

3 citations , January 2025 in “动物学研究”

The gene GJA1 is important for regulating coarse hair density in goats.

research Diguanoside tetraphosphate (Gp₄G) is an epithelial cell and hair growth regulator.

2 citations , February 2012 in “PubMed”

Gp₄G promotes hair growth and improves skin health.

research LGR5 is a Conserved Marker of Hair Follicle Stem Cells Across Species and is Present Early and Throughout Follicle Morphogenesis

February 2022 in “Research Square (Research Square)”

LGR5 is a marker found in hair follicle stem cells in various species and is important for hair growth and skin repair.

research The topical penta-peptide Gly-Pro-Ile-Gly-Ser increases the proportion of thick hair in Japanese men with androgenetic alopecia

3 citations , March 2016 in “Journal of Cosmetic Dermatology”

GPIGS peptide increases thick hair growth in balding Japanese men.

research The retarded hair growth ( rhg ) mutation in mice is an allele of ornithine aminotransferase ( Oat )

9 citations , January 2014 in “Molecular Genetics and Metabolism Reports”

The rhg mutation in mice affects the Oat gene, causing hair growth issues and other symptoms.

research Expression of MsPG3‐GFP fusions in Medicago truncatula‘hairy roots’ reveals preferential tip localization of the protein in root hairs

18 citations , December 2002 in “European Journal of Biochemistry”

MsPG3 protein gathers at root hair tips, aiding growth.

research Arabinogalactan proteins are involved in root hair development in barley

32 citations , December 2014 in “Journal of experimental botany”

Certain proteins are essential for the growth of root hairs in barley.

research Introduction: Contributions of the Cooperative Groups

September 2008 in “Seminars in Oncology”

research Megasessions

7 citations , August 2013 in “Facial Plastic Surgery Clinics of North America”

Megasessions in hair transplant can cover more area or increase density but need a skilled team and careful planning, and have both benefits like less downtime and risks like lower graft survival.

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