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research A HISTOCHEMICAL TEST FOR CITRULLINE ADAPTATION OF THE CARBAMIDO DIACETYL REACTION TO HISTOLOGIC SECTIONS WITH POSITIVE RESULTS IN PILOMATRIXOMAS (CALCIFYING EPITHELIOMAS)

20 citations , February 1968 in “Journal of Histochemistry & Cytochemistry”

A new test more accurately detects citrulline in hair follicles and pilomatrixomas.

research APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex

199 citations , April 2010 in “Nature”

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

research Enzyme Inhibitors from Gorgonians and Soft Corals

4 citations , January 2023 in “Marine Drugs”

Marine compounds from gorgonians and soft corals show promise for drug development, especially for chronic disorders.

Oxidative Activity of the Type 2 Isozyme of 17β-Hydroxysteroid Dehydrogenase Predominates in Human Sebaceous Glands

research Oxidative Activity of the Type 2 Isozyme of 17β-Hydroxysteroid Dehydrogenase (17β-HSD) Predominates in Human Sebaceous Glands

45 citations , September 1998 in “Journal of Investigative Dermatology”

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Macroscopic Evaluation of the Effect of Topically Applied Tideglusib with Bacterial Cellulose-Based Hydrogel Carrier on the Healing of Induced Palatal Wounds in Rats: A Preliminary Study

research Bakteriyel Selüloz Tabanlı Hidrojel Taşıyıcı ile Topikal Uygulanan Tideglusib’in Sıçanlarda Oluşturulan Palatinal Yaranın İyileşmesi Üzerine Etkisinin Makroskobik Değerlendirmesi: Bir Öncül Çalışma

1 citations , January 2023 in “European Journal of Research in Dentistry”

Tideglusib with a bacterial cellulose hydrogel improves wound healing in rats.

research Substrate specific sulfatase activity from hair follicles in recessive X-linked ichthyosis

8 citations , September 1987 in “Acta Dermato Venereologica”

Recessive X-linked ichthyosis involves a less efficient enzyme in hair follicles, suggesting two distinct enzymes.

research Characterization of tiger tail banding and hair shaft abnormalities in trichothiodystrophy

7 citations , March 2004 in “Journal of the American Academy of Dermatology”

Tiger tail banding and hair abnormalities are reliable indicators for diagnosing trichothiodystrophy.

research Changes in Hair: Causative Factors

January 1996

DHT, not testosterone, mainly affects hair growth and related conditions.

research Depletion of Gsdma1/2/3i> alleviates PMA-induced epidermal hyperplasia by inhibiting the EGFR–Stat3/Akt pathway

6 citations , December 2023 in “Journal of Molecular Cell Biology”

Removing Gsdma1/2/3 genes reduces skin cell overgrowth by blocking a specific cell pathway.

research Long-read RNA sequencing reveals extensive transcript isoform changes in a patient with IFAP syndrome with a recurrent intronic MBTPS2 variant
April 2026 in “Human Genome Variation”

Long-read RNA sequencing can identify complex gene changes in IFAP syndrome.

research Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile
January 2022 in “Figshare”

Autophagy helps mouse glands stay healthy, prevents early aging, and maintains their oil and scent production.

research Inducible, reversible hair loss in transgenic mice.
3 citations , June 2002 in “Transgenic Research”

Scientists made a mouse that can be made to lose hair and then grow it back.

research One Transgene: Two Outcomes
July 2002 in “Science s STKE”

Modified β-catenin causes different effects in hair and skin cells, leading to cysts or tumors.

research Overexpression of protein kinase C-α in the epidermis of transgenic mice results in striking alterations in phorbol ester-induced inflammation and COX-2, MIP-2 and TNF-α expression but not tumor promotion
135 citations , October 1999 in “Journal of Cell Science”

Overexpressing PKCα in mice skin increases inflammation but doesn't affect tumor growth.

research Photosensitive Trichothiodystrophy with Complex Cerebral Abnormalities
April 2012 in “Neuropediatrics”

Trichothiodystrophy is a rare genetic disorder causing hair issues and sometimes linked to DNA repair defects.

research An Integrated Two-Step Enzymatic Unhairing Strategy: Eliminating the Penetration Barrier via Soaking To Enhance Targeted Protease Action
April 2026 in “Industrial & Engineering Chemistry Research”

The new method speeds up leather unhairing and improves quality.

research Proteolysis‐targeting chimeras in cancer therapy: Targeted protein degradation for next‐generation treatment
3 citations , October 2025 in “Cancer”

PROTACs offer a new, precise way to treat cancer by breaking down harmful proteins.

research A TP63 Mutation Causes Prominent Alopecia with Mild Ectodermal Dysplasia
2 citations , May 2020 in “The journal of investigative dermatology/Journal of investigative dermatology”

A TP63 gene mutation causes significant hair loss and mild skin, nail, and tooth abnormalities.

research Expression of the human Cathepsin L inhibitor hurpin in mice: skin alterations and increased carcinogenesis
21 citations , August 2007 in “Experimental Dermatology”

Overexpression of hurpin in mice leads to abnormal skin and higher skin cancer risk.

research Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile
6 citations , September 2021 in “Autophagy”

Autophagy prevents early aging and maintains lipid and pheromone balance in mouse glands.

research Transforming Growth Factor-β Receptor Type I and Type II Expression During Murine Hair Follicle Development and Cycling
148 citations , October 1997 in “Journal of Investigative Dermatology”

research A homozygous missense variant in type I keratin KRT25i> causes autosomal recessive woolly hair
29 citations , July 2015 in “Journal of Medical Genetics”

A genetic variant in the KRT25 gene causes tightly curled hair.

research Identification of the C-terminal tail domain of AHF/trichohyalin as the critical site for modulation of the keratin filamentous meshwork in the keratinocyte
12 citations , December 2011 in “Journal of Dermatological Science”

The C-terminal tail of AHF/trichohyalin is essential for organizing keratin filaments in keratinocytes.

research Overexpression of insulin-like growth factor-1 induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice
147 citations , April 1997 in “Oncogene”

Overexpressing IGF-1 in mice leads to skin abnormalities and tumors.

research 715 Hunting the hair cycle clock (HCC): Evidence that mitochondrially localized MPZL3 is a key HCC element in murine and human hair follicles
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

MPZL3 is important for controlling the hair growth cycle in mice and humans.

research Decision letter: Structural basis of malodour precursor transport in the human axilla
March 2018

The study identified a key protein involved in producing underarm odor and found ways to inhibit it.

research A missense mutation in the type II hair keratin hHb3 is associated with monilethrix
79 citations , March 2005 in “Journal of Medical Genetics”

A mutation in the hHb3 gene is linked to the hair disorder monilethrix.

research Establishment of type II 5α-reductase over-expressing cell line as an inhibitor screening model
12 citations , June 2007 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

research Promotion of anagen, increased hair density and reduction of hair fall in a clinical setting following identification of FGF5-inhibiting compounds via a novel 2-stage process
27 citations , February 2017 in “Clinical, Cosmetic and Investigational Dermatology”

New compounds were found to help increase hair growth and decrease hair loss.

research Expression patterns of TRα and CRABPII genes in Chinese cashmere goat skin during prenatal development
August 2015 in “Han'gug dongmul jawon gwahag hoeji/Han-guk dongmul jawon gwahak hoeji/Journal of animal science and technology”

TRα and CRABPII genes change their activity levels during goat fetal skin development.

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