research The Burden of Alopecia Areata and Management with Baricitinib in the United Arab Emirates: A Narrative Review
Baricitinib is a promising treatment for alopecia areata in the UAE, but there are challenges with data and access.
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research Acanthosis Nigricans during an HAIR-AN syndrome: "The Tree That Hides the Forest"
The case shows skin changes can indicate deeper health issues like insulin resistance, which are challenging to manage.
research Treatment of frontal fibrosing alopecia and lichen planopilaris: a systematic review
No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.
research CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment
CD80 on skin stem cells helps expand Treg cells to aid wound healing.
research The Hair Follicle Bulge: A Niche for Adult Stem Cells
The hair follicle bulge is an important area for adult stem cells involved in hair growth and repair, with potential for medical use needing more research.
research Stereocontrolled synthesis of all eight stereoisomers of the putative anti-androgen cyoctol
Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.
research Inhibition of 5α Reductase Impairs Cognitive Performance, Alters Dendritic Morphology and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice
Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.
research Clionasterol-Rich Fraction of Caulerpa racemosa against Particulate Matter-Induced Skin Damage via Inhibition of Oxidative Stress and Apoptosis-Related Signaling Pathway
A substance from Caulerpa racemosa seaweed may protect against skin damage caused by air pollution by reducing oxidative stress and cell death.
research Scanning electron microscopy of murine skin ultrathin sections and cultured keratinocytes
The document outlined a protocol for using scanning electron microscopy (SEM) to examine the ultrastructure of murine skin and cultured keratinocytes, focusing on details like the epidermis, dermis, hair follicles, and cell-cell junctions. It described the preparation of ultrathin sections and cell monolayers, including steps like fixation, dehydration, and embedding, with an emphasis on proper sample orientation. The study utilized both male and female mice, with newborn pups for cell monolayer protocols and 3-8 week old animals for skin samples. The protocol enabled visualization of skin structures such as hair follicles and sebaceous glands, as well as subcellular structures like cell junctions and mitochondria. Limitations of SEM, such as its resolution compared to TEM, were discussed, along with troubleshooting tips for common issues in sample preparation and imaging.
research Therapeutic implications of topical cetirizine 1% in treatment of male androgenetic alopecia: A case‐controlled study
Topical cetirizine 1% promotes hair growth in male androgenetic alopecia patients.
research Rice Bran Polysaccharides: Structure, Modification, Bioactivity, and Application Potential in Food and Health Systems
Rice bran polysaccharides have potential uses in food, health, and cosmetics due to their beneficial bioactive properties.
research Air Wedge Interferometry for Microscopic Thickness Measurement of Human Hair
Air wedge interferometry is a precise, cost-effective way to measure hair thickness.
research AYURVEDIC COSMETOLOGY APPROACHES TO PREMATURE HAIR GREYING (AKĀLAPĀLITYA): A LITERATURE REVIEW
Ayurveda suggests natural remedies and lifestyle changes for managing premature hair greying.
research Stress-induced sympathetic hyperactivation drives hair follicle necrosis to trigger autoimmunity
Stress can cause hair loss and trigger autoimmunity by damaging hair follicle cells.
research Topical Application of Bio-Pulsed Avian MSC-Derived Extracellular Vesicles Enhances Hair Regrowth and Skin Rejuvenation: Evidence from Clinical Evaluation and miRNA Profiling
Bio-Pulsed sEVs improve hair growth and skin rejuvenation.
research The integrated stress response fine-tunes stem cell fate decisions upon serine deprivation and tissue injury
Serine is vital for hair follicle stem cells to balance hair growth and skin repair.
research Molecular mechanism for transcriptional regulation of the parathyroid hormone gene by Epiprofin
Epiprofin suppresses parathyroid hormone gene activity, helping regulate calcium levels and could be a treatment target for hyperparathyroidism.
research The Potential Teeth Bleaching and Halitosis Prevention Effects of Pediococcus inopinatus THK-30, a Kimchi-Derived Lactic Acid Bacterium: In Vitro Study
A kimchi-derived bacterium could help whiten teeth and prevent bad breath.
research Microarray Gene Expression Analysis of Lesional Skin in Canine Pemphigus Foliaceus
Canine pemphigus foliaceus involves significant immune activity and shares similarities with human pemphigus.
research An mTurq2-Col4a1 mouse model allows for live visualization of mammalian basement membrane development
The mTurq2-Col4a1 mouse model shows how the basement membrane develops in live mammals.
research Study of Antibacterial activity of Mulethi and Amla against gram negative bacteria Escherichia coli
Mulethi and Amla effectively kill E. coli bacteria.
research Study of Antibacterial activity of Mulethi and Amla against gram negative bacteria Escherichia coli
Mulethi and Amla effectively kill E. coli bacteria.
research Correction to: Enhanced Follicular Delivery of Finasteride to Human Scalp Skin Using Heat and Chemical Penetration Enhancers
research Successful Treatment of Alopecia Areata with Topical Calcipotriol
A boy with alopecia regrew hair using a vitamin D cream after other treatments failed.
research Novel skin patch combining human fibroblast-derived matrix and ciprofloxacin for infected wound healing
The new skin patch with human matrix and antibiotic improves wound healing.
research Ursolic acid reduces prostate size and dihydrotestosterone level in a rat model of benign prostatic hyperplasia
Ursolic acid can shrink the prostate and lower a hormone linked to prostate growth in rats.
research Androgen receptor gene CAG repeat polymorphism in women with polycystic ovary syndrome
Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.
research Prevalence of Common Skin Diseases and Their Associated Factors among Military Personnel in Korea: A Cross-sectional Study
Over 60% of Korean military personnel had skin diseases, commonly acne and athlete's foot, linked to service length and stress.
research Exploring nanobioceramics in wound healing as effective and economical alternatives
Nanobioceramics can effectively and cheaply heal wounds without side effects.
research Effect of Pumpkin Seed Oil on Hair Growth in Men with Androgenetic Alopecia: A Randomized, Double-Blind, Placebo-Controlled Trial
Pumpkin seed oil helps hair growth in men with hair loss.