research Development of growth factor-incorporating liposomes for integration into scaffolds as a method to improve tissue regeneration
Liposomal carriers can improve tissue regeneration by stabilizing and retaining growth factors.
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research Molecular basis of androgen action on human sexual desire
Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.
research Androgen receptor activation integrates complex transcriptional effects in osteoblasts, involving the growth factors TGF-β and IGF-I, and transcription factor C/EBPδ
DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.
research Tailored chromatin modulation to promote tissue regeneration
Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
research Repurposing steroidogenesis inhibitors for the therapy of neuropsychiatric disorders: Promises and caveats
Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.
research Evaluation of the Tolerability of Hedgehog Pathway Inhibitors in the Treatment of Advanced Basal Cell Carcinoma: A Narrative Review of Treatment Strategies
Hedgehog pathway inhibitors for advanced basal cell carcinoma can cause side effects, but managing them helps maintain treatment.
research Recommendations of endocrine treatment for patients with gender dysphoria
The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.
research LETTERS TO THE EDITOR
Careful management of blood thinners is crucial for lupus patients with APS.
research Application and Progress of Cultured Models of Gallbladder Carcinoma
Advancements in cultured models improve understanding and treatment of gallbladder cancer.
research Keratin function and regulation in tissue homeostasis and pathogenesis
Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.
research Rodent models in placental research. Implications for fetal origins of adult disease
Using rodents for research shows that health problems in the womb can cause diseases later in life.
research Platelet-Rich Plasma for Degenerative Spine Disease: A Brief Overview
PRP shows promise for spinal pain but needs more guidelines before widespread use.
research Septin4 promotes cell death in human colon cancer cells by interacting with BAX
Septin4 helps kill colon cancer cells by working with the protein BAX.
research Effective high-throughput isolation of enriched platelets and circulating pro-angiogenic cells to accelerate skin-wound healing
Angio PRP speeds up skin wound healing and reduces inflammation.
research Abstracts from the 55th European Society of Human Genetics (ESHG) Conference: Oral Presentations
NIPT can help detect potential maternal cancer, and GIPXplore can identify immune diseases in pregnancies.
research Sustainable applications of phytochemicals and nutritive components derived from selected underutilized seeds: A review [pdf]
Underutilized seeds like jackfruit, Indian almond, and tamarind have valuable nutrients and compounds that can be used sustainably in various industries.
research PINK1 deficiency rewires early immune responses in a mouse model of Parkinson’s disease triggered by intestinal infection
PINK1 is important for controlling gut immune responses linked to early Parkinson's disease.
research Functional characterization of OR51B5 and OR1G1 in human lung epithelial cells as potential drug targets for non-type 2 lung diseases
Blocking certain receptors in the lungs might help treat a specific type of asthma.
research Three-dimensional models: from cell culture to Patient-Derived Organoid and its application to future liposarcoma research
3D models and organoids improve liposarcoma research and therapy development.
research Use of Minced Residual Skin Grafts to Improve Donor Site Healing in Split-Thickness Skin Grafting
Minced skin grafts speed up healing and improve scar quality at donor sites.
research ELL Facilitates RNA Polymerase II–Mediated Transcription of Human Epidermal Proliferation Genes
ELL is crucial for gene transcription related to skin cell growth.
research Estrogen modulates mesenchymal-epidermal interactions in the adult nipple
Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
research A Tale of Two Haplotypes: The EDA2R/AR Intergenic Region is the Most Divergent Genomic Segment between Africans and East Asians in the Human Genome
The most different genetic segment between Africans and East Asians is the EDA2R/AR region, with two main types influenced by population changes and natural selection, and linked to baldness.
research Clinical Assessment of Anti-inflammatory Activity of 940 Nanometer Low Level laser Therapy on Carrageenan Induced Arthritis in Temporomandibular Joint in Wistar Albino Rats
A 940nm laser effectively reduces inflammation in rat joints.
research Intraethnic variation in steroid-5-alpha-reductase polymorphisms in prostate cancer patients: a potential factor implicated in 5-alpha-reductase inhibitor treatment
Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.
research Beneficial uses of Breadfruit (Artocarpus altilis)
Breadfruit is nutritious and has potential health and medicinal benefits, but is currently underused.
research Application of Platelet-Rich Plasma as a Stem Cell Treatment - anAttempt to Clarify a Common Public Misconception
PRP is not a stem cell treatment and should not be marketed as such.
research Microneedles as a perspective for transdermal therapeutic systems
Microneedles could make it easier and less painful to deliver more types of drugs through the skin.
research Deep skin fibroblast-mediated macrophage recruitment supports acute wound healing
Deep skin fibroblasts help recruit immune cells for better wound healing.
research Commercially and medicinally significant aquatic macrophytes: potential for improving livelihood security of indigenous communities in northern Bihar, India
Aquatic plants in northern Bihar are vital for local livelihoods and need protection and sustainable management.