21 citations
,
November 2010 in “Journal of molecular medicine” FoxN1 gene is essential for proper thymus structure and preventing hair loss.
19 citations
,
August 2024 in “Journal of Translational Medicine” Epidermal stem cells are vital for skin healing and have potential for treating skin disorders.
13 citations
,
January 2021 in “Journal of Cellular and Molecular Medicine” Thymosin β4 may boost hair growth by aiding stem cell movement and blood vessel formation.
7 citations
,
September 2020 in “International Journal of Cosmetic Science” Different sizes of keratin peptides can strengthen hair, with smaller ones possibly increasing volume and larger ones repairing damage.
7 citations
,
November 1987 in “Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy” Minoxidil can help thicken hair in some people with male pattern baldness, especially if used early and continuously.
4 citations
,
May 2025 in “Cells” miR-370-3p slows sheep hair cell growth by blocking SMAD4.
4 citations
,
January 2000 Piedraia hortae fungi dissolve both the outer and inner layers of hair.
3 citations
,
August 2018 in “Journal of Structural Biology” KAP8.1 protein is crucial for hair structure and interacts with keratin 85.
3 citations
,
March 2009 in “Hirosaki University Repository for Academic Resources (Hirosaki University)” Hirosaki hairless rats have sparse, twisted hair due to missing hair keratin genes.
2 citations
,
March 2023 in “BMC ecology and evolution” Some hair protein genes evolved early and were adapted for use in hair follicles.
2 citations
,
December 2022 in “Journal of toxicologic pathology” Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.
2 citations
,
January 1997 in “Journal of Clinical Biochemistry and Nutrition” Biotin deficiency causes severe hair loss and weight reduction in germ-free mice.
1 citations
,
July 2023 in “Communications biology” Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.
1 citations
,
January 2015 in “Journal of nutrition & health” Fish oil improves skin health in people with diabetes and high cholesterol.
1 citations
,
April 2008 in “Pigment Cell & Melanoma Research” Foxn1 is essential for hair pigmentation by directing pigment transfer to hair cells.
May 2025 in “Journal of Extracellular Vesicles” Erythrocyte extracellular vesicles help hair growth and skin health.
Nanocarriers with plant extracts show promise for safe and effective hair growth treatment.
January 2017 in “Journal of Investigative Dermatology Symposium Proceedings” The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
52 citations
,
April 2012 in “Journal of Investigative Dermatology” KRTAP2 genes are crucial for hair structure and may impact hair disorders and treatments.
27 citations
,
August 2014 in “Wiley interdisciplinary reviews. Developmental biology” The skin and thymus develop similarly to protect and support immunity.
19 citations
,
April 2016 in “Experimental Dermatology” Melanoblasts migrate to the skin using various pathways, and understanding this process could help with skin disease research.
January 2025 in “Frontiers in Medicine” Hair follicles are key to treating vitiligo and alopecia areata, but challenges exist.
December 2013 in “Research Portal (King's College London)” Hair loss in Lichen Planopilaris is caused by immune system issues damaging hair follicles and stem cells.
338 citations
,
April 2001 in “Current Biology” c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.
2 citations
,
January 2012 in “InTech eBooks” Chemotherapy often causes hair loss, which usually grows back within 3 to 6 months, but there's no effective treatment to prevent it.
1 citations
,
January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Dicer is crucial for hair growth in mice.
May 2018 in “White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)” Alopecia areata may be treated by using EGCG to balance immune cells and reduce inflammation.
788 citations
,
February 2007 in “Nature” The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
309 citations
,
October 2007 in “Biomaterials” Keratin from human hair helps nerves heal faster.
215 citations
,
September 2003 in “Journal of Biological Chemistry” Vitamin D receptor and hairless protein are essential for hair growth.