March 1985 in “Head & Neck Surgery” Hair transplantation improves life quality by addressing scars, aging, and genetic flaws, but is limited by the availability of the patient's own hair for donation.
72 citations
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July 2012 in “Journal of Investigative Dermatology” Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
April 2017 in “Journal of Investigative Dermatology” Certain compounds can protect hair cells from aging and promote growth.
57 citations
,
January 2019 in “Stem Cell Research & Therapy” OCT4 helps hair stem cells renew and fight aging, potentially aiding hair regrowth.
January 2025 in “Research” Cellular senescence can both hinder and promote hair growth, suggesting new ways to treat hair loss.
March 2018 in “Surgical and Radiologic Anatomy” High-resolution imaging is crucial for diagnosing and planning treatments in clinical anatomy and aging.
December 2014 in “TDX (Tesis Doctorals en Xarxa)” Cellular senescence is crucial for normal embryonic development but contributes to aging in adults.
January 2012 in “Else Kröner-Fresenius Symposia” Maintaining DNA integrity in stem cells is crucial to prevent aging and cancer.
9 citations
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February 2021 in “Frontiers in Cell and Developmental Biology” Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
7 citations
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March 2022 in “The FASEB journal” Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.
6 citations
,
June 2017 in “Asian journal of beauty & cosmetology” Rosa multiflora root extracts may help promote hair growth and have anti-aging benefits.
5 citations
,
May 2024 in “Journal of Cosmetic Dermatology” Engineered nanovesicles from hair follicle stem cells can effectively treat UVB-induced skin aging.
1 citations
,
May 2024 in “Communications Biology” Dab2 protein is crucial for hair follicle stem cell renewal and preventing early aging.
4 citations
,
November 2022 in “Nutrients” Cow placenta extract has strong antioxidant effects and can delay skin aging in mice.
July 2025 in “Biotechnology and Bioprocess Engineering” Camellia japonica seed extract helps hair grow by activating hair follicles and preventing cell aging.
2 citations
,
September 2023 in “International journal of molecular sciences” Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.
February 2024 in “International Journal of Molecular Sciences” Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.
13 citations
,
September 2021 in “Current Issues in Molecular Biology” Dexpanthenol helps human hair follicle cells grow by preventing aging and death, and by supporting growth signals.
May 2024 in “Journal of Advanced Research” Communication between blood vessel and hair follicle cells decreases with age, affecting hair growth and blood vessel formation.
17 citations
,
February 2018 in “Journal of Investigative Dermatology” PPAR-γ signaling improves mitochondrial function in hair follicles, potentially affecting hair growth and aging.
3 citations
,
April 2022 in “Research Square (Research Square)” PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.
November 2024 in “BMC Research Notes” SIRT3 and SIRT7 genes may play a role in hair loss.
July 2024 in “Research Square (Research Square)” SIRT3 and SIRT7 decrease, while NFATC1 and PDL-1 increase in Androgenetic Alopecia.
12 citations
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August 2022 in “Stem cell reviews and reports” Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.
3 citations
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July 2020 in “International Journal of Molecular Sciences” SCDSFs from zebrafish embryos are beneficial for treating cancer, regenerating tissues, and improving conditions like psoriasis and alopecia.
65 citations
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January 2018 in “Nature Reviews Endocrinology” Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.
144 citations
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September 2012 in “Genes & development” Aging causes skin stem cells to work less effectively.
138 citations
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May 2000 in “Maturitas” Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.
128 citations
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October 2011 in “Development” Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.
119 citations
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August 2010 in “Journal of Investigative Dermatology” Increased 11β-HSD1 activity in skin may contribute to aging and could be targeted to reduce aging effects.