31 citations
,
August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
31 citations
,
September 2020 in “Stem Cell Research & Therapy” Hair follicle stem cells may help repair the brain after a stroke.
30 citations
,
September 2004 in “Experimental Dermatology” Scalp hair follicle culture has limits for testing minoxidil's hair growth effects.
29 citations
,
April 2020 in “Journal of Tissue Engineering and Regenerative Medicine” The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
28 citations
,
October 2019 in “Seminars in Cell & Developmental Biology” Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.
27 citations
,
October 2020 in “Biomedicine & Pharmacotherapy” Hair follicle stem cells help skin heal and grow better.
25 citations
,
March 2017 in “Experimental Dermatology” The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.
25 citations
,
April 2008 in “Archives of Dermatological Research” Encapsulated human hair cells can substitute for natural hair cells to grow hair.
24 citations
,
November 2013 in “Molecular Medicine Reports” Human hair follicle stem cells can become endothelial cells with certain growth factors, useful for vascular treatments.
21 citations
,
January 2018 in “The Korean Journal of Physiology and Pharmacology” Modified stem cells from umbilical cord blood can make hair grow faster.
20 citations
,
August 2015 in “International Journal of Molecular Medicine” Human placental extract may help hair growth by affecting certain cell signals and could be more effective with minoxidil.
19 citations
,
June 2021 in “Tissue Engineering and Regenerative Medicine” Fat stem cell particles help regrow hair.
19 citations
,
March 2017 in “PLoS ONE” PSU are better than THF at regenerating skin layers in lab models.
18 citations
,
August 2015 in “International Journal of Molecular Sciences” Ovine hair follicle stem cells can regenerate haired skin and may improve wool production.
16 citations
,
August 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” MED1 is essential for normal hair growth and maintaining hair follicle stem cells.
15 citations
,
May 2022 in “Journal of Investigative Dermatology” Endothelial TLR2 is crucial for timely wound healing, but HFSC TLR2 is not needed.
15 citations
,
February 2021 in “Scientific Reports” A specific group of stem cells can help regenerate hair continuously.
12 citations
,
February 2023 in “Stem Cell Research & Therapy” HGF-modified hair follicle stem cells help brain recovery after injury in rats.
12 citations
,
July 2020 in “Aging” The protein EZH2 blocks microRNA-22, increasing STK40 protein, which helps hair follicle stem cells change and grow hair.
11 citations
,
February 2019 in “Stem cells international” Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.
10 citations
,
May 2020 in “Frontiers in cell and developmental biology” MicroRNAs are important for hair growth regulation, with Dicer being crucial and Tarbp2 less significant.
10 citations
,
April 2020 in “PloS one” Lack of Crif1 in hair follicle stem cells slows down hair growth in mice.
10 citations
,
October 2019 in “Iranian Biomedical Journal” Simvastatin helps hair follicle stem cells turn into skin cells.
9 citations
,
January 2005 in “Experimental dermatology” Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.
8 citations
,
June 2022 in “Scientific Reports” LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.
8 citations
,
April 2017 in “Journal of Dermatological Science” Hair loss is caused by the breakdown of a protein called COL17A1 in hair follicle stem cells.
7 citations
,
March 2017 in “Experimental and Therapeutic Medicine” Hair follicle cells can help keep embryonic stem cells undifferentiated.
6 citations
,
October 2022 in “Frontiers in Cell and Developmental Biology” Transplanted hair follicle stem cells can heal damaged rat intestines.
6 citations
,
July 2018 in “Advances in Clinical and Experimental Medicine” Different body parts have varying levels of certain hair follicle markers.
5 citations
,
January 2023 in “Cell proliferation” Chick embryo extract helps rat hair follicle stem cells potentially turn into Schwann cells, important for the nervous system.