3 citations
,
June 2006 in “Expert Review of Dermatology” The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.
18 citations
,
August 2015 in “International Journal of Molecular Sciences” Ovine hair follicle stem cells can regenerate haired skin and may improve wool production.
27 citations
,
August 2021 in “Journal of Autoimmunity” Human dermal γδT-cells respond to stress in hair follicles, contributing to hair loss.
November 2022 in “Journal of Investigative Dermatology” Butyrate helps hair grow longer, improves hair cell health, increases pigment production, and boosts hair's natural defenses.
14 citations
,
September 2001 in “Archives of Dermatological Research” Blocking hair follicle development stops key gene signals needed for hair growth in mice.
November 2025 in “Biomolecules” FGF22 helps hair follicle stem cells grow and develop.
25 citations
,
March 2022 in “International journal of biological macromolecules” miR-181a-5p helps hair growth by activating a specific signaling pathway.
January 2026 in “Non-coding RNA Research” Exosomal miRNA-218-5p promotes hair growth and development.
64 citations
,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Human stem cells can help form hair follicles in mice.
September 2024 in “Journal of the American Academy of Dermatology” Regulatory γδ T cells help protect hair follicles from alopecia areata and promote hair regrowth.
7 citations
,
March 2023 in “Journal of Investigative Dermatology” Low-intensity ultrasound may help protect hair follicles from chemotherapy-induced hair loss.
64 citations
,
March 2005 in “Journal of Investigative Dermatology” Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.
3 citations
,
February 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.
10 citations
,
September 2022 in “Cellular and Molecular Life Sciences” SOX9 is essential for the development of various organs and hair follicles.
57 citations
,
February 1994 in “Experimental dermatology” Melatonin affects mouse skin and may regulate skin functions.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking mTORC1 activity with rapamycin could help increase hair pigmentation and growth, potentially reversing gray hair.
12 citations
,
December 2022 in “Current Protein and Peptide Science” Thymosin β4 helps in cell activities, healing, and organ preservation, and treats hair loss and skin injuries.
299 citations
,
January 2018 in “Journal of Clinical Investigation” Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
291 citations
,
April 2010 in “Gastroenterology” Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.
64 citations
,
January 2010 in “The FASEB Journal” Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.
69 citations
,
June 2017 in “Experimental Biology and Medicine” Advanced human skin models improve drug development and could replace animal testing.
2 citations
,
January 2012 in “InTech eBooks” Chemotherapy often causes hair loss, which usually grows back within 3 to 6 months, but there's no effective treatment to prevent it.
3 citations
,
February 2005 in “Aktuelle Dermatologie” Prolactin and TGF-β receptor blockers might help treat hair loss.
August 2023 in “Bioengineering” Bioprinting could greatly improve health outcomes but faces challenges like material choice and ensuring long-term survival of printed tissues.
August 2023 in “Military Medical Research” Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
1′S-1′-Acetoxychavicol acetate may help treat hair loss by reducing oxidative stress.
49 citations
,
February 2014 in “Clinical Cosmetic and Investigational Dermatology” Furunculosis is a recurring skin infection needing careful hygiene and treatment to manage and prevent spread.
January 2026 in “Wound Repair and Regeneration” Skin organoids are improving research but need better blood supply, nerve function, and immune system integration.
72 citations
,
January 2012 in “Annals of Dermatology” IGF-I promotes hair growth by keeping hair follicles in the growth phase longer.
46 citations
,
January 2020 in “Theranostics” Injecting a special gel with human protein particles can help hair grow.