January 2012 in “ScholarlyCommons (University of Pennsylvania)” miRNAs are crucial for hair growth and skin health.
21 citations
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May 2022 in “Frontiers in Cell and Developmental Biology” Hair growth and health are influenced by factors like age, environment, and nutrition, and are controlled by various molecular pathways. Red light can promote hair growth, and understanding these processes can help treat hair-related diseases.
January 2000 in “BioScience” The document concludes that understanding hair biology is key to treating hair disorders, with gene therapy showing potential as a future treatment.
271 citations
,
March 1999 in “Developmental biology” The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.
January 2026 in “Theoretical and Natural Science” Targeting Lgr5+ stem cells and Wnt signaling may effectively treat hair loss.
414 citations
,
August 2005 in “Nature” Activating TERT in mice skin boosts hair growth by waking up hair follicle stem cells.
245 citations
,
October 2015 in “Nature medicine” Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
194 citations
,
May 2000 in “Journal of Investigative Dermatology” The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.
75 citations
,
October 1999 in “Differentiation” Mouse keratin 6 isoforms have different expression patterns in various tissues.
73 citations
,
October 2003 in “Journal of Pharmacology and Experimental Therapeutics” Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.
73 citations
,
April 1999 in “Dermatologic Clinics” Lasers and light sources can effectively remove hair, work best on fair skin with dark hair, and usually need multiple treatments.
61 citations
,
August 1993 in “PubMed” Basal cell epithelioma likely starts from the hair follicle's outer root sheath.
43 citations
,
December 2006 in “The American journal of pathology” Edar signaling is crucial for controlling hair growth and regression.
30 citations
,
July 2010 in “Experimental Dermatology” Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.
26 citations
,
December 2006 in “Endocrinology” A cream with a specific hormone blocker increases hair growth in mice.
23 citations
,
September 2020 in “Journal of Dermatological Science” Targeting Vδ1+T-cells may help treat alopecia areata.
23 citations
,
January 2018 in “BMC genomics” Vimentin is involved in regulating the hair growth cycle in Inner Mongolian Cashmere goats.
20 citations
,
October 2008 in “Archives of dermatological research” Angiogenin helps hair grow by stimulating cell growth and blood vessel formation.
13 citations
,
July 2019 in “PLoS ONE” Deleting podoplanin in mice promotes hair growth by enhancing cell migration.
9 citations
,
January 2008 in “Acta histochemica et cytochemica” COX-2 levels change during the hair cycle and affect skin and hair growth.
4 citations
,
December 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.
2 citations
,
February 2017 in “International Journal of Molecular Sciences” Erdr1 could be a new marker for diagnosing hair loss.
1 citations
,
April 2025 in “BMC Veterinary Research” PSAT1 is key for hair growth and stem cell function in cashmere goats.
1 citations
,
January 2022 in “Cell Biology International” Changing CDK4 levels affects the number of stem cells in mouse hair follicles.
Low-intensity ultrasound may prevent hair loss during taxane chemotherapy.
September 2025 in “Biomolecules” The skin microenvironment significantly affects hair growth and loss, offering potential treatment avenues.
February 2025 in “Science Advances” Wnt signaling helps regenerate hair follicles by affecting how skin cells sense and respond to mechanical forces.
September 2023 in “Nature communications” Alk1 in specific cells is crucial for proper nerve branching and hair function.
January 2014 in “Pathology” Non-scarring hair loss can be diagnosed with two 4mm punch biopsies, one cut vertically and the other transversely.
10 citations
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May 2009 in “Cases Journal” A woman's masculine symptoms were caused by an ovarian tumor, which improved after surgery.