218 citations
,
January 2013 in “The Lancet Oncology” Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
103 citations
,
January 2006 in “Journal of Cell Science” The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.
92 citations
,
June 2005 in “Journal of Investigative Dermatology” All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.
65 citations
,
July 2020 in “Science Advances” Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.
44 citations
,
April 2017 in “Genes & development” Scientists found cells in hair that are key for growth and color.
39 citations
,
December 2011 in “PLoS ONE” Radiofrequency exposure can stimulate hair growth by increasing IGF-1 in hair follicle cells.
31 citations
,
August 2000 in “Journal of Investigative Dermatology” Stem cells are key for hair follicle recovery.
23 citations
,
October 2021 in “Cell Stem Cell” Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.
17 citations
,
December 2001 in “Journal of Investigative Dermatology” The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.
70 citations
,
February 2017 in “Dermatologic Surgery” Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.
207 citations
,
July 2006 in “Development” MTS24 marks a new type of skin cell that helps hair growth and repair.
23 citations
,
January 2002 in “Journal of Cutaneous Medicine and Surgery” Finasteride helps hair growth by decreasing cell death in hair follicles.
76 citations
,
August 2018 in “International Journal of Cosmetic Science” Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
60 citations
,
June 1997 in “Journal of The American Academy of Dermatology” Apoptosis is crucial for healthy skin and treating skin diseases.
1 citations
,
December 2023 in “Biomolecules” Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.
61 citations
,
September 2010 in “Genomics” The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.
4 citations
,
March 2024 in “Journal of Investigative Dermatology” SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.
277 citations
,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.
10 citations
,
January 2019 in “Biomarker Insights” Scalp cooling to prevent hair loss from chemotherapy works for some but not all, and studying hair damage markers could improve prevention and treatment.
10 citations
,
January 2016 in “PLOS ONE” Researchers found 44 proteins that change during different hair growth stages and may be important for hair follicle function.
November 2023 in “Nature Communications” Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.
February 2023 in “International Journal of Molecular Sciences” Exosomes from skin cells can boost hair growth by stimulating a gene called LEF1.
174 citations
,
April 2005 in “The American journal of pathology (Print)” Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.
58 citations
,
January 2006 in “Skin Pharmacology and Physiology” High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
31 citations
,
April 2007 in “Experimental Dermatology” Stress in mice delays hair growth and treatments blocking substance P can partly reverse this effect.
7 citations
,
March 2018 in “Experimental Dermatology” Acne lesions don't show increased keratinocyte growth compared to healthy hair follicles.
3 citations
,
September 2021 in “Journal of Food Science and Nutrition” Red Ginseng Extract helps hair grow and improves skin health by stimulating cell growth and enhancing the body's antioxidant defense system.
4 citations
,
October 2022 in “Frontiers in public health” Cadmium chloride pollution can cause skin disorders, speed up aging, and prevent hair growth.
146 citations
,
May 2002 in “The American journal of pathology” Cathepsin L is essential for normal hair growth and development.
46 citations
,
August 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” Phosphatidic acid may help hair grow by affecting cell growth pathways.