Treating vitiligo with stem cells and melanocytes from hair, along with UVB light, works better than without the light.
Activin A increases inner ear hair cell development, while follistatin decreases it.
April 2018 in “Journal of Investigative Dermatology” Glycogen metabolism is important for energy and processes in human hair follicles, and hair follicles may produce glucose from lactate.
April 2018 in “Journal of Investigative Dermatology” Stabilizing HIF1A in hair follicles increases glycolysis, which may help reduce oxidative stress and support hair growth.
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
173 citations
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January 2014 in “Nature Cell Biology” Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.
6 citations
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November 2020 in “Molecular and Cellular Endocrinology” Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.
26 citations
,
July 2016 in “PLOS ONE” Activating β-catenin in certain skin cells speeds up hair growth in mice.
184 citations
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November 2014 in “Developmental Cell” Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.
134 citations
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January 2010 in “Biomedical research” Low oxygen conditions increase the hair-growing effects of substances from fat-derived stem cells by boosting growth factor release.
95 citations
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July 2010 in “Genes & development” Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
83 citations
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March 2015 in “International Journal of Dermatology” ADSC-CM treatment improved hair density and thickness in women with hair loss, safely and effectively.
81 citations
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December 2009 in “Journal of Dermatological Science” Fat tissue stem cells may help increase hair growth.
80 citations
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June 2008 in “Biomaterials” EVAL membranes help create cell structures that can regrow hair follicles.
51 citations
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September 2020 in “Cell Metabolism” Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
42 citations
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February 2018 in “International Journal of Molecular Sciences” Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.
42 citations
,
January 2017 in “Stem cells international” Adding hyaluronic acid helps create larger artificial hair follicles in the lab.
30 citations
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July 2017 in “Stem cells and cloning” SVF-enhanced adipose transplantation shows potential as a hair loss treatment.
21 citations
,
March 2019 in “Experimental Dermatology” Immune cells around hair follicles help control hair growth and could be targets for treating hair disorders.
21 citations
,
March 2017 in “Skin research and technology” Removing external lipids from hair reduces moisture and increases strength, while removing internal lipids decreases water permeability.
14 citations
,
April 2000 in “Animal Science/Animal science” Nutrients like vitamins, copper, zinc, and amino acids are crucial for healthy hair and wool growth.
11 citations
,
January 2018 in “Acta dermato-venereologica” Researchers found specific genes in the part of hair follicles that could help treat hair disorders.
9 citations
,
April 2019 in “Journal of structural biology” Hair's internal fibers are arranged in a pattern that doesn't let much water in, and treatments like oils and heat change how much water hair can absorb.
8 citations
,
January 2009 in “Transactions of the Materials Research Society of Japan” Water-soluble wool keratin can protect human hair from damage during treatments.
5 citations
,
January 2022 in “PloS one” Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.
4 citations
,
January 2015 in “Sen'i Gakkaishi” Hair and wool strength is affected by the number and type of bonds in their protein structures, with hair having more protein aggregates than wool.
2 citations
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March 2021 in “Molecular Immunology” Dermal macrophages might help regrow hair.
2 citations
,
May 2002 in “Clinics in Dermatology” Ethnic differences in hair and skin are significant and under-researched, requiring tailored dermatologic treatments and more study.
1 citations
,
May 2021 in “Research Square (Research Square)” Micro-injury can help regrow hair and repigment vitiligo by activating specific cells.
1 citations
,
April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” mTORC1 activity is important for hair growth and color, and targeting it could help treat hair loss and greying.