91 citations
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November 2008 in “Journal of biological chemistry/The Journal of biological chemistry” DGAT1 enzyme is crucial for healthy skin and hair by regulating retinoid levels.
89 citations
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April 2023 in “Forensic Science International Genetics” Forensic DNA Phenotyping can now better predict appearance, ancestry, and age from DNA, but more research is needed for precise police use.
89 citations
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March 2001 in “Endocrine practice” The guidelines help doctors diagnose and treat hormone-related disorders in women.
81 citations
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February 2014 in “EMBO molecular medicine” Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.
66 citations
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February 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.
54 citations
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June 2020 in “Pharmaceutics” New nanocarriers improve drug delivery for disease treatment.
52 citations
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February 2003 in “Archives of dermatology” 9-cis-retinoic acid showed some effectiveness in treating AIDS-related Kaposi sarcoma but had significant side effects at higher doses.
50 citations
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August 2021 in “Stem Cell Research & Therapy” Adipose-derived stem cells help heal radiation skin damage by reducing cell death and inflammation.
48 citations
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September 2020 in “Frontiers in Immunology” Loss of OGG1 increases skin inflammation and auto-antibodies in lupus.
45 citations
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August 2018 in “Haematologica” Macrophage iron release is crucial for hair growth and wound healing.
42 citations
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September 2012 in “PLoS ONE” Bezafibrate treatment improved skin and spleen health in aging mice but didn't extend lifespan.
39 citations
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April 2019 in “The journal of immunology/The Journal of immunology” Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.
36 citations
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March 2014 in “Molecular and Cellular Biology” Cidea is essential for proper lipid storage and secretion in sebaceous glands, affecting skin and hair health.
27 citations
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April 2017 in “British Journal of Dermatology” Hair loss involves immune responses, inflammation, and disrupted signaling pathways.
27 citations
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April 2017 in “Journal of Investigative Dermatology” After skin is damaged, noncoding dsRNA helps prostaglandins and Wnts work together to repair tissue and promote hair growth.
22 citations
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December 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” A mouse gene mutation increases the risk of skin cancer.
21 citations
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June 2024 in “Pharmaceuticals” Swellable microneedles could improve drug delivery and diagnostics but need more research on materials and technology integration.
21 citations
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September 2015 in “International journal of gynaecology and obstetrics” Chemotherapy is crucial for treating gynecological cancers but requires careful management due to severe side effects.
19 citations
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July 2024 in “Journal of Cellular and Molecular Medicine” Astaxanthin may reduce inflammation in women with PCOS, but doesn't significantly improve symptoms.
18 citations
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February 2023 in “eLife” ILC1-like cells can independently cause alopecia areata.
18 citations
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July 2022 in “Frontiers in Immunology” Volatile organic compounds can cause inflammation and increase the risk of autoimmune diseases.
18 citations
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June 2010 in “Cell Stress and Chaperones” Heat treatment increases hair loss in certain mice.
17 citations
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September 2016 in “Stem cells translational medicine” Using bioreactors, scientists can grow more skin stem cells that keep their ability to regenerate skin and hair.
15 citations
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May 2014 in “Journal of Biological Chemistry” A chimeric keratin partially improved skin structure in mice lacking keratin 5, but didn't fully restore normal skin.
14 citations
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May 2016 in “International Journal of Molecular Sciences” PP2Acα is essential for proper hair and skin development.
9 citations
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November 2013 in “BMC Pharmacology and Toxicology” Suppressing eIF4E can prevent hair loss from chemotherapy.
8 citations
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July 2021 in “Patient Preference and Adherence” Alopecia treatments improve life quality but side effects can lessen this benefit; better use of quality of life measures is needed.
8 citations
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February 2017 in “International journal of molecular sciences” Mollusc egg extract helps skin and hair cells grow and heal.
7 citations
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March 2022 in “The FASEB journal” Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.
7 citations
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January 2022 in “Scientific Reports” Acanthus ebracteatus Vahl. extract and verbascoside may help prevent hair loss and promote hair growth due to their anti-inflammatory properties and ability to protect against cell death.