1 citations
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January 2024 in “Microorganisms” Mice with a virus similar to COVID-19 had skin damage, but a special treatment helped repair it.
The document concludes that the new model realistically simulates male baldness and could be useful for medical purposes and entertainment.
April 2018 in “Journal of Investigative Dermatology” Researchers found that the Leptin receptor is a consistent marker for hair follicle dermal cells, which may help future hair research.
188 citations
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June 1998 in “Molecular cell” Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.
69 citations
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February 2008 in “The American journal of pathology” Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.
59 citations
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September 2008 in “Experimental dermatology” Both mouse and rat models are effective for testing alopecia areata treatments.
48 citations
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September 2020 in “Frontiers in Immunology” Loss of OGG1 increases skin inflammation and auto-antibodies in lupus.
47 citations
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November 2012 in “Wound repair and regeneration” Nude mice with grafted human skin developed scars similar to human hypertrophic scars.
37 citations
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April 2010 in “FEBS Letters” The study concludes that the EDA2R gene is activated by p53 during chemotherapy but is not necessary for chemotherapy-induced hair loss.
35 citations
,
June 2017 in “Pharmaceutical research” Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.
31 citations
,
January 2021 in “Experimental Dermatology” Skin organoids are a promising new model for studying human skin development and testing treatments.
27 citations
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June 2023 in “Nature” Senescent melanocytes can boost hair growth by activating hair stem cells.
27 citations
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December 2013 in “Endocrinology” Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.
25 citations
,
August 2014 in “Endocrinology” Researchers created a mouse model of a type of rickets that does not cause hair loss.
18 citations
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June 2010 in “Cell Stress and Chaperones” Heat treatment increases hair loss in certain mice.
17 citations
,
July 2024 in “Frontiers in Oncology” New therapies and trials are needed for Merkel cell carcinoma, a tough skin cancer.
16 citations
,
February 2019 in “Journal of Cellular and Molecular Medicine” Researchers created a rat model to study skin damage caused by radiation, which could help develop new treatments.
13 citations
,
January 2015 in “Steroids” The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.
10 citations
,
April 2020 in “PloS one” Lack of Crif1 in hair follicle stem cells slows down hair growth in mice.
9 citations
,
January 2022 in “Biology” Male mice are more susceptible to autism-like changes from valproic acid than female mice.
8 citations
,
January 2016 in “Evidence-based Complementary and Alternative Medicine” Rumex japonicus extract may promote hair growth more effectively than Minoxidil.
6 citations
,
February 2024 in “JAAD International” ChatGPT is preferred for creating dermatology patient handouts, but all models can be useful with oversight.
6 citations
,
January 2007 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Gray hair regained color after thyroid hormone treatment.
4 citations
,
November 2021 in “Frontiers in Cell and Developmental Biology” Aging causes hair loss and graying due to stem cell decline and changes in cell behavior and communication.
1 citations
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October 2019 in “PubMed” Removing the p75 gene in mouse skin cells didn't affect their skin or hair growth.
January 2026 in “Mendeley Data” Hair follicle stem cell exosomes help nerve regeneration.
January 2026 in “Mendeley Data” Hair follicle stem cell exosomes help nerve regeneration.
January 2026 in “Lab on a Chip” Organoids and hair-on-chip technologies show promise for hair regeneration but face clinical challenges.
December 2025 in “Mycoses” The study developed a successful mouse model to study skin infections, highlighting the importance of choosing the right fungal strains.
AI models are effective for detecting alopecia areata but face challenges like explaining results and data bias.