January 2008 in “Journal of Clinical Dermatology” Integrin alpha-6 and p63 proteins may play a role in hair loss and are important for hair growth and maintenance.
November 2025 in “Biomedicines” Targeting pyroptosis may offer new treatments for alopecia areata, but more research is needed.
60 citations
,
April 2018 in “Clinical, cosmetic and investigational dermatology” Tight hairstyles and chemical relaxers can cause hair loss known as traction alopecia.
3 citations
,
December 2013 in “Journal of Dermatology” Scanning electron microscopy revealed four distinct hair root shapes in alopecia areata, suggesting a less invasive diagnostic method.
2 citations
,
January 2023 in “BMC plant biology” Scientists found new genetic areas that affect how rice root hairs grow and develop.
25 citations
,
December 1992 in “Seminars in cell biology” Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
Hair follicle stem cells can be cultured, but better methods are needed for longer growth.
90 citations
,
June 2006 in “The American Journal of Dermatopathology” The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.
8 citations
,
March 2009 in “Differentiation” Adult vibrissa follicle stem cells can regenerate hair follicles, glands, and skin.
April 2012 in “Informa Healthcare eBooks” The document concludes that diagnosing hair loss requires evaluating multiple histological features, as no single feature is definitive on its own.
17 citations
,
April 1997 in “American Journal of Dermatopathology” PC-associated alopecia has unique microscopic features.
November 2025 in “Journal of Investigative Dermatology” Radiation-induced hair loss may be caused by hair growth stopping and inflammation in blood vessels.
April 2023 in “Journal of Investigative Dermatology” The research developed methods to test drugs that could protect and restore hair follicle protection in a hair loss condition.
87 citations
,
February 2000 in “Journal of Investigative Dermatology” Stem cells in developing hair follicles move to specific areas as they mature.
19 citations
,
July 2011 in “Microscopy and Microanalysis” The hair follicle bulge is an important area for adult stem cells involved in hair growth and repair, with potential for medical use needing more research.
18 citations
,
January 2019 in “Experimental Dermatology” Certain cells outside the hair follicle's bulge area can quickly regenerate damaged hair follicles, potentially helping to reduce hair loss from cancer treatments.
February 2024 in “Scientific reports” Four genes are potential markers for hair loss condition alopecia areata, linked to a specific type of cell death.
7 citations
,
October 2008 in “Nature Genetics” Two key genetic areas linked to male-pattern baldness were identified.
2 citations
,
June 2021 in “Notulae Botanicae Horti Agrobotanici Cluj-Napoca” More research is needed to understand how nutrients affect root hair growth.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Activating mitophagy may help manage a key immune response involved in the hair loss condition alopecia areata.
4 citations
,
October 2018 in “Experimental Dermatology” Dermoscopy shows that diffuse alopecia areata progresses through specific hair growth stages.
66 citations
,
December 2016 in “Frontiers in Plant Science” Some rice types grow better roots for phosphorus uptake, but not all do.
26 citations
,
October 2017 in “Scientific reports” A special microbe helps plants absorb rock phosphate by growing on their root hairs.
December 2017 in “International Journal of Current Research in Biosciences and Plant Biology” Nutrients and hormones affect root hair growth, but more research is needed to understand the genetic mechanisms.
December 2025 in “Russian Journal of Skin and Venereal Diseases” Hair follicles are thinner in alopecia patients, especially in alopecia areata.
171 citations
,
July 2007 in “Journal of Investigative Dermatology” A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.
March 2014 in “Journal of The American Academy of Dermatology” TNF-a may not be as involved in certain types of hair loss as previously thought.
April 2012 in “Informa Healthcare eBooks” Syphilitic alopecia is a rare hair loss condition in secondary syphilis that looks similar to another condition but can be diagnosed with specific tests and responds to antibiotics.
20 citations
,
February 1968 in “Journal of Histochemistry & Cytochemistry” A new test more accurately detects citrulline in hair follicles and pilomatrixomas.
2 citations
,
April 2024 in “Journal of Dermatological Science” Necrosulfonamide helps hair grow by blocking a protein linked to hair loss.