63 citations
,
July 2006 in “British Journal of Dermatology” Psoriasis causes changes in certain keratins and shrinks sebaceous glands in the scalp.
26 citations
,
May 2017 in “Lasers in Medical Science” Laser therapy and hair growth factors significantly improve hair density in male baldness.
New treatments for hair loss, including a compound called "ALRV5XR", platelet-rich plasma, and Adult Stem Cell-based therapy, are showing promise, but more trials are needed for confirmation.
2 citations
,
September 2017 in “Biotechniques/BioTechniques” Researchers created a mouse cell line to study hair growth and test hair growth drugs.
308 citations
,
September 2010 in “Nucleic acids research” Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.
555 citations
,
July 2001 in “Genes & Development” Tcf3 and Lef1 are key in deciding skin stem cell roles.
January 2006 in “Durham e-Theses (Durham University)” Id proteins, especially Id2 and Id3, are crucial for hair follicle development and stem cell regulation.
205 citations
,
August 2007 in “Experimental Cell Research” Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.
September 2019 in “Journal of Investigative Dermatology” BMPs are important for hair growth and can counteract the negative effects of androgens on hair follicle stem cells.
59 citations
,
March 2003 in “The Lancet” Imatinib can repigment grey hair, while SU11428 can cause temporary hair depigmentation.
August 2009 in “Mechanisms of Development” Adult hair follicle cells can create new hair follicles from corneal cells with the right support.
11 citations
,
June 2019 in “Tissue & Cell” Hair stem cells produce a protein called COL17A1 that plays a key role in their development and is linked to hair thinning and baldness.
13 citations
,
September 2016 in “Journal of Cellular Biochemistry” Low oxygen levels help hair follicle stem cells turn into heart muscle cells faster.
105 citations
,
April 2005 in “Cell” Hair graying happens because certain cells aren't maintained properly.
135 citations
,
December 2013 in “Seminars in Cell & Developmental Biology” Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.
January 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.
169 citations
,
January 2018 in “Cell Reports” Scientists grew hair follicles from mouse stem cells in a lab setting.
135 citations
,
October 2010 in “Stem Cells” Hair follicle stem cells can help treat eye surface issues by becoming corneal cells.
4 citations
,
January 2021 in “Cell transplantation” Scientists found the best time to transplant human stem cells for hair growth is between days 16-18 when they have the right markers and growth potential.
3 citations
,
September 2019 in “Clinical and experimental dermatology” Basal cell carcinomas may differentiate similarly to hair follicles and could be influenced by hair cycle-related treatments.
11 citations
,
June 2021 in “Frontiers in Cell and Developmental Biology” Melatonin helps goat hair stem cells grow and maintain their ability to become different cell types.
90 citations
,
August 2004 in “Physiological Genomics” Dermal papilla cells help skin stem cells grow into hair.
33 citations
,
April 2020 in “Journal of Clinical Investigation” Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.
24 citations
,
June 2015 in “Journal of Investigative Dermatology” aPKCλ is crucial for keeping hair follicle stem cells inactive and maintaining normal hair growth.
31 citations
,
September 2013 in “Stem Cells” Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.
January 2022 in “Stem cell biology and regenerative medicine” iPSCs could help develop treatments for hair loss.
September 2016 in “Journal of Dermatological Science” The protein aPKCλ is crucial for keeping hair follicle stem cells inactive and for hair growth and regeneration.
28 citations
,
January 2023 in “Cell Transplantation” Nanofat with stem cells is promising for treating hair loss, scars, and skin rejuvenation.
January 2006 in “Yearbook of Dermatology and Dermatologic Surgery” Hair graying is caused by the loss of pigment cells due to poor maintenance of stem cells in the hair follicle.
24 citations
,
November 2013 in “Molecular Medicine Reports” Human hair follicle stem cells can become endothelial cells with certain growth factors, useful for vascular treatments.