32 citations
,
January 2006 in “Acta dermato-venereologica” SACUMAN, a rare condition causing hair loss without clear signs, is often misdiagnosed and needs scalp biopsies for accurate detection.
26 citations
,
September 2001 in “Journal of Investigative Dermatology” BSSP may help skin tumors grow and could be a marker or target for skin cancer treatment.
24 citations
,
December 2018 in “Life sciences” Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
23 citations
,
August 2018 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
21 citations
,
September 2015 in “Journal of the European Academy of Dermatology and Venereology” Yellow and orange colors are important for diagnosing certain skin conditions.
19 citations
,
July 1993 in “Journal of Applied Toxicology” Different oil products cause varying levels of skin irritation in mice, which could potentially lead to tumors.
8 citations
,
January 2018 in “Journal of Analytical Methods in Chemistry” A new method accurately measures a drug in skin for cancer therapy research.
8 citations
,
January 2017 in “Journal of Oral and Maxillofacial Pathology” Keratoacanthomas on lips may originate differently than those on skin.
7 citations
,
October 2011 in “BMC Cancer” Overexpression of HDGF in melanocytes does not cause cancer.
2 citations
,
May 2025 in “Frontiers in Immunology” Ursolic acid may help develop new anti-inflammatory drugs by affecting immune cells.
2 citations
,
June 2022 in “Life” A 14-year-old boy is the youngest person reported with a rare, benign tumor related to hair follicles, usually found in older people.
September 2025 in “Egyptian Journal of Dermatology and Venerology” Dermoscopy is crucial for diagnosing rare scalp tumors like trichofolliculoma.
December 2021 in “International journal of research - granthaalayah” A young woman had a rare, usually non-cancerous tumor on her face that was initially mistaken for a different condition.
August 2017 in “Journal of Investigative Dermatology” Activin increases skin tumor formation, skin Tregs help hair growth, lymph-node removal doesn't improve melanoma survival, cells can revert to stem cells in wound healing, and skin bacteria produce peptides that may treat infections.
October 2012 in “Humana Press eBooks” Grape seed extract is good for skin care, with antioxidant, anti-inflammatory, and anti-cancer effects.
7 citations
,
January 1990 in “Archives of Dermatological Research” Syringomas likely start in the upper dermis and form distinct luminal structures.
November 2021 in “CRC Press eBooks” Anagen effluvium is a reversible condition causing sudden hair loss, often due to chemotherapy or head radiation.
January 1994 in “Medical Entomology and Zoology” Electron microscopy helps understand skin structure and diseases.
6 citations
,
January 1985 in “ACTA HISTOCHEMICA ET CYTOCHEMICA” Tumor cells in calcifying epithelioma of Malherbe resemble hair follicle cells.
April 2024 in “Cell death and differentiation” Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.
129 citations
,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
86 citations
,
May 2008 in “Cytokine & growth factor reviews” TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.
84 citations
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May 2008 in “Biological Chemistry” Human tissue kallikreins help regulate skin barrier functions and affect skin health.
60 citations
,
May 2015 in “Archives of dermatological research” PPAR agonists show promise for skin conditions but need more research before being a main treatment.
60 citations
,
June 1997 in “Journal of The American Academy of Dermatology” Apoptosis is crucial for healthy skin and treating skin diseases.
57 citations
,
March 2018 in “International Journal of Molecular Sciences” The extracellular matrix is crucial for controlling skin stem cell behavior and health.
54 citations
,
June 2008 in “Planta Medica” Hinokitiol may help treat hair loss by reducing inflammation and promoting hair growth.
54 citations
,
May 2001 in “Journal of Investigative Dermatology” Excessive putrescine causes hair loss in transgenic mice by disrupting hair follicle development.
48 citations
,
July 2019 in “International Journal of Biological Macromolecules” A new hydrogel with stem cells from human umbilical cords improves skin wound healing and reduces inflammation.
29 citations
,
March 2012 in “Stem Cell Research & Therapy” Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.