13 citations
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December 2017 in “Stem cells” Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.
150 citations
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October 2010 in “The American Journal of Pathology” The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
141 citations
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May 2007 in “Cancer Research” CD34 is crucial for skin tumor development in mice.
76 citations
,
July 2011 in “Clinical, Cosmetic and Investigational Dermatology” The document concludes that proper diagnosis and FDA-approved treatments for different types of hair loss exist, but treatments for severe cases often fail and future improvements may focus on hair follicle stem cells.
41 citations
,
March 2007 in “Journal of dermatological science” Taking L-cystine and vitamin B6 can prevent hair loss caused by smoke in mice.
15 citations
,
May 2022 in “Journal of Investigative Dermatology” Endothelial TLR2 is crucial for timely wound healing, but HFSC TLR2 is not needed.
12 citations
,
January 2022 in “Cells” Dermal papilla cell vesicles can boost hair growth genes in fat stem cells.
6 citations
,
November 2018 in “American journal of transplantation” UV light helped human hair transplants survive in mice without broad immunosuppression.
5 citations
,
September 2021 in “Frontiers in Cell and Developmental Biology” Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.
4 citations
,
September 2020 in “Frontiers in Microbiology” Algal oligosaccharides help prevent hair loss and promote hair growth.
2 citations
,
August 2022 in “BMC veterinary research” Hair follicle stem cells from Arbas Cashmere goats can become fat, nerve, and liver cells.
August 2024 in “Cell Death and Disease” Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.
August 2016 in “Journal of Investigative Dermatology” Blocking the CCR5 receptor may be a new way to treat hair loss from alopecia areata.
September 2013 in “Experimental Dermatology” The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
February 2024 in “Molecules/Molecules online/Molecules annual” NMN could potentially treat hair loss by reducing oxidative stress and improving cell health.
July 2024 in “International Journal of Molecular Sciences” Nannochloropsis salina fermented oil may help treat hair loss by promoting hair growth and reducing oxidative stress.
57 citations
,
March 2019 in “Immunity” The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
3 citations
,
November 2022 in “International journal of molecular sciences” Bio-pulsed stimulation increases production of beneficial vesicles from bird stem cells that improve skin and hair cell functions.
November 2025 in “Biomolecules” FGF22 helps hair follicle stem cells grow and develop.
February 2025 in “Biomolecules” RORA boosts autophagy in hair follicle stem cells, potentially aiding hair growth.
December 2024 in “Animals” RORA may help regulate hair growth by affecting hair follicle stem cells.
85 citations
,
July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
39 citations
,
March 2018 in “Archives of Dermatological Research” Androgens may block hair growth signals, targeting this could treat hair loss.
8 citations
,
September 2017 in “Journal of Investigative Dermatology” CXXC5 is a protein that prevents hair growth and could be a target for hair loss treatment.
June 2025 in “Theranostics” Rapamycin-primed exosomes can significantly boost hair regrowth.
February 2025 in “Applied Sciences” Scenedesmus deserticola JD052 extracts may help hair growth and could be a natural treatment for hair loss.
1 citations
,
July 2025 in “Biomaterials Advances” 3D cultures respond better to minoxidil, while 2D cultures respond better to DHT.
January 2023 in “Journal of Cosmetics, Dermatological Sciences and Applications” The hair growth serum Trichosera® was effective in increasing hair regrowth and density and reducing hair fall without significant side effects.
338 citations
,
July 2009 in “Development” Sox2-positive cells determine specific hair follicle types in mammals.
218 citations
,
April 2008 in “Genes & Development” Skin stem cells help repair damage and maintain healthy skin.