research Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin
Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
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research Skin organoids: A new human model for developmental and translational research
Skin organoids are a promising new model for studying human skin development and testing treatments.
research Investigation of transfollicular caffeine penetration using microdialysis on ex vivo porcine ear skin
Caffeine penetrates skin quickly through open hair follicles, but less through closed ones, with levels becoming equal after 22 hours.
research Potential of Nanoparticles as Permeation Enhancers and Targeted Delivery Options for Skin: Advantages and Disadvantages
Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.
research Penetration and storage of particles in human skin: Perspectives and safety aspects
Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.
research Niacinamide: A B Vitamin that Improves Aging Facial Skin Appearance
Niacinamide improves aging skin and is safe for use in cosmetics.
research Physicochemical properties of pH-sensitive hydrogels based on hydroxyethyl cellulose–hyaluronic acid and for applications as transdermal delivery systems for skin lesions
The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.
research Surface Lipids as Multifunctional Mediators of Skin Responses to Environmental Stimuli
Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.
research In Vitro Percutaneous Permeation and Skin Accumulation of Finasteride Using Vesicular Ethosomal Carriers
Ethosomes improve finasteride delivery through skin for hair loss treatment.
research Skin aging: are adipocytes the next target?
Targeting dermal adipocytes may help combat skin aging.
research Measurement of Skin Permeation/Penetration of Nanoparticles for Their Safety Evaluation
Nanoparticles don't penetrate intact skin but can enter through pores or damaged skin.
research Focus on Skin as a Possible Port of Entry for Solid Nanoparticles and the Toxicological Impact
Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.
research Skin aging as a mechanical phenomenon: The main weak links
Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.
research Nobiletin-loaded composite penetration enhancer vesicles restore the normal miRNA expression and the chief defence antioxidant levels in skin cancer
Nobiletin-loaded vesicles effectively treat skin cancer by restoring normal miRNA and antioxidant levels.
research In Vitro and In Vivo Skin Distribution of 5α-Reductase Inhibitors Loaded Into Liquid Crystalline Nanoparticles
Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.
research Skin Penetration and Permeation Properties of Transcutol® in Complex Formulations
Transcutol® helps drugs penetrate the skin more effectively in various formulations.
research Aromatic plants as cosmeceuticals: benefits and applications for skin health
Aromatic plants can naturally help prevent skin aging and improve skin health.
research Invasomes: Vesicles for Enhanced Skin Delivery of Drugs
Invasomes effectively deliver drugs through the skin and have potential for improved treatments.
research A novel approach to manage skin toxicity caused by therapeutic agents targeting epidermal growth factor receptor
New treatment with green tea polyphenols and nicotinamide improves skin problems from cancer therapy.
research Penetration and Distribution in Human Skin Focusing on the Hair Follicle
Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.
research Vascular endothelial cells as signaling niches for epithelial stem cells in the skin
Vascular endothelial cells may significantly influence skin stem cells, but more research is needed.
research Rheological Properties and Composition Affecting the Skin Permeation of a Model of a Hydrophilic Drug in Lecithin Reverse Wormlike Micelles
IPM enhances skin penetration of hydrophilic drugs.
research Skin wound healing in humans and mice: Challenges in translational research
The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
research Wnt Signaling in Skin Development, Homeostasis, and Disease
Wnt signaling is crucial for skin development and health, and its disruption can cause skin diseases.
research The endocannabinoid system of the skin. A potential approach for the treatment of skin disorders
Targeting the skin's endocannabinoid system could help treat skin disorders.
research Physical methods for topical skin drug delivery: concepts and applications
New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.
research Role of umbilical cord mesenchymal stromal cells in skin rejuvenation
Umbilical cord cells may help delay skin aging.
research Skin Biology: Understanding Biological Targets for Improving Appearance
The document concludes that a deeper understanding of skin aging and photodamage is needed to create better skin treatments.
research Scratching the surface of skin development
The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
research More than one way to skin . . .
Skin stem cells help repair damage and maintain healthy skin.