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research SIRT1-modified human umbilical cord mesenchymal stem cells ameliorate experimental peritoneal fibrosis by inhibiting the TGF-β/Smad3 pathway

17 citations , August 2020 in “Stem Cell Research & Therapy”

The study investigated the therapeutic potential of SIRT1-modified human umbilical cord mesenchymal stem cells (hUCMSCs) for treating peritoneal fibrosis, a complication of long-term peritoneal dialysis. By overexpressing SIRT1 in hUCMSCs, researchers found that these modified cells had a stronger anti-fibrosis effect compared to regular hUCMSCs. They significantly inhibited fibrotic gene expression, suppressed the epithelial-mesenchymal transition process, increased ultrafiltration volume, and restored the balance of bioincompatible factors in dialysis solutions. The mechanism involved reducing peritoneal inflammation and inhibiting the TGF-β/Smad3 pathway. The findings suggested that SIRT1-modified hUCMSCs could be a promising therapeutic strategy for peritoneal dialysis-induced peritoneal damage and fibrosis.

research Novel Compound Heterozygous Variants in the CDC6 Gene in a Russian Patient with Meier-Gorlin Syndrome

2 citations , January 2022 in “The Application of Clinical Genetics”

A young Russian girl with Meier-Gorlin syndrome has two new mutations in the CDC6 gene.

research AP collagen peptides (APCPs) promote hair growth by activating the GSK‐3β/β‐catenin pathway and improve hair condition

July 2024 in “Experimental Dermatology”

AP collagen peptides help hair grow and improve hair health.

HPV8 E6 Induced STAT3 Activation Leads to Hair Follicle Junctional Zone Keratinocyte Stem Cell Proliferation and Expansion in Actinic Keratoses

research 277 HPV8 E6 induced STAT3 activation leads to hair follicle junctional zone keratinocyte stem cell proliferation and expansion in actinic keratoses

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

HPV8 causes hair follicle stem cells to grow, leading to skin lesions.

research Bilateral anterior uveitis as a presenting manifestation of sarcoidosis and syphilis

4 citations , August 2002 in “British Journal of Ophthalmology”

Surgical excision is the best treatment for SCC.

research Dermatologic Conditions of the Early Post-Transplant Period in Hematopoietic Stem Cell Transplant Recipients

5 citations , October 2018 in “American Journal of Clinical Dermatology”

Skin problems are common after stem cell transplants, and early treatment by dermatologists can improve patient outcomes.

research Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine

773 citations , August 2017 in “International Journal of Molecular Sciences”

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

research Epidermal and Hair Follicle Progenitor Cells Express Melanoma-Associated Chondroitin Sulfate Proteoglycan Core Protein

51 citations , February 2004 in “Journal of Investigative Dermatology”

MCSP may help identify and regulate skin stem cells, affecting hair growth and regeneration.

research Micropore-forming photocurable tissue adhesive promotes cell infiltration for wound healing

September 2025 in “Acta Biomaterialia”

A new tissue adhesive helps wounds heal better by allowing more cells to enter.

research 707 Guiding skin organoid generation via extracellular matrix cues and spatially controlled morphogen gradients

July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Scientists improved how to make skin-like structures from stem cells using special gels and a device that controls growth signals, leading to better hair and skin features.

research Small molecules facilitate single factor-mediated sweat gland cell reprogramming

9 citations , March 2022 in “Military Medical Research”

Small molecules can help turn skin cells into sweat gland-like cells for potential skin repair.

research Graham Little-Lassueur Syndrome with Hypertrophic Lichen Planus in a Patient with Chronic Hepatitis C

February 2016 in “Acta Medica Marisiensis”

A woman with chronic hepatitis C had a rare skin condition linked to her illness.

research MSF-VMDNet for multi class segmentation of skin cancer whole slide images using a multi frequency dual encoder network

April 2026 in “Scientific Reports”

MSF-VMDNet accurately segments skin cancer images better than existing methods.

research Establishment and molecular characterization of human dermal mesenchymal-like stem cells derived from human scalp biopsy of androgenetic alopecia patient

4 citations , January 2013 in “Stem cell discovery”

Researchers created a cell line from a hair follicle to study hair loss.

research Downregulation of Sonic hedgehog signaling induces G2‐arrest in genital warts

4 citations , December 2022 in “Skin Research and Technology”

Reduced Sonic hedgehog signaling leads to increased HPV replication and wart formation.

research Integration of Point-of-Care Technology in the Decoding Process of Single Nucleotide Polymorphism for Healthcare Application †

1 citations , October 2025 in “Micromachines”

Portable point-of-care testing can improve quick and accurate genetic disorder detection.

research pH-Responsive Nanogels from Bioinspired Comb-like Polymers with Hydrophobic Grafts for Effective Oral Delivery

1 citations , October 2025 in “Gels”

Nanogels with hydrophobic modifications improve oral drug delivery for intestinal disease treatment.

research Identification of Somatic KRAS Mutation in a Korean Baby with Nevus Sebaceus Syndrome

3 citations , December 2014 in “Annals of Laboratory Medicine”

A Korean baby with nevus sebaceus syndrome was found to have a KRAS gene mutation.

research Next-generation Sequencing Identified a Novel EDA Mutation in a Chinese Pedigree of Hypohidrotic Ectodermal Dysplasia with Hyperplasia of the Sebaceous Glands

4 citations , January 2017 in “Acta dermato-venereologica”

A new EDA gene mutation was found in a Chinese family with a specific skin disorder.

research The HEDGEHOG-GLI1 pathway is important for fibroproliferative properties in keloids and as a candidate therapeutic target

December 2023 in “Communications biology”

Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.

research Decision letter: Coordinated hedgehog signaling induces new hair follicles in adult skin

May 2019

Hedgehog signaling can create new hair follicles but may also cause tumors.

research An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasis

99 citations , September 2004 in “Development”

Proper hedgehog signaling is crucial for maintaining healthy skin stem cells.

research A randomized controlled clinical trial of recombinant interferon α‐2b in the treatment of acute post‐transfusion hepatitis C: A preliminary report

17 citations , January 1993 in “Journal of Gastroenterology and Hepatology”

Interferon α‐2b can temporarily reduce hepatitis C virus and normalize liver enzyme levels.

research Isolation and characterization of a sheep cysteine-rich cuticle keratin pseudogene

1 citations , January 1992 in “DNA sequence”

Researchers found a non-functional sheep keratin gene due to mutations.

PBX Homeobox 1 Enhances Hair Follicle Mesenchymal Stem Cell Proliferation and Reprogramming Through Activation of the AKT/Glycogen Synthase Kinase Signaling Pathway and Suppression of Apoptosis

research PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis

26 citations , August 2019 in “Stem Cell Research & Therapy”

PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.

research P-017 CUSHING'S SYNDROME DUE TO PRIMARY BILATERAL MACRONODULAR ADRENAL HYPERPLASIA AND METACRONOUS PHEOCHROMOCYTOMA

January 2026 in “JCEM Case Reports”

A rare case of Cushing's syndrome and pheochromocytoma requires careful re-evaluation to avoid complications.

research 560 Isolation of an “early” transit amplifying keratinocyte population in interfollicular human epidermis: a role for CD271 receptor

November 2022 in “Journal of Investigative Dermatology”

Scientists found a new type of skin cell that could help with skin repair and these cells work better with a certain protein.

research Case Report: Pulsed electric field treatment of metastatic liver disease demonstrating a possible abscopal response

April 2026 in “UNC Libraries”

Pulsed electric field treatment may help shrink untreated liver tumors.

research Identifying SARS-CoV-2 entry inhibitors through drug repurposing screens of SARS-S and MERS-S pseudotyped particles

20 citations , July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

Six existing drugs may help block virus entry in COVID-19.

research Hair Cycle-Dependent Expression of Hepatocyte Growth Factor (HGF) Activator, Other Proteinases, and Proteinase Inhibitors Correlates with the Expression of HGF in Rat Hair Follicles

33 citations , December 1999 in “Journal of Investigative Dermatology Symposium Proceedings”

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