research Hair Follicle Culture
Hair follicle culture helps study hair growth but has limitations in modeling the full hair cycle.
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research Evaluation of hair follicles as a surrogate tissue for pharmacodynamics response in xenograft tumors
Hair follicles can be used to quickly assess drug effects in cancer treatment.
research Reproduction of the human relevant potency threshold (HRPT) for estrogen receptor alpha agonism in an inference performance screen for ICCVAM’s regulatory scientific confidence framework
A new method effectively predicts estrogen-related health effects for early screening.
research 368 Methods in Inflammatory Hair Disease Research: Enhanced Multiplex Imaging on Alopecia Areata Tissue Sections
New imaging technology can show up to 40 different markers in hair loss tissue, helping to understand hair disease better.
research Invalidation of a commercially available human 5α-dihydrotestosterone immunoassay
The DHT immunoassay is unreliable due to high cross-reactivity with testosterone.
research Effect of beta--catenin on regulating hair follicle cells' proliferation
Beta-catenin boosts hair follicle cell growth by increasing c-myc expression.
research Differential metabolic adaptations define responses of winner and loser oncogenic mutant stem cells in skin epidermisin vivo
Mutant stem cells adapt their metabolism differently to outcompete normal cells in the skin.
research Testosterone-like immunoreactivity in hair measured in minute sample amounts - a competitive radioimmunoassay with an adequate limit of detection
The new test can measure very small amounts of testosterone in hair, and grinding the hair up first gives more accurate results.
research A method for culturing human hair follicle cells
A new method helps grow human hair cells using a cow eye lens.
research Isoproterenol directs hair follicle-associated pluripotent (HAP) stem cells to differentiate in vitro to cardiac muscle cells which can be induced to form beating heart-muscle tissue sheets
Isoproterenol helps hair follicle stem cells turn into beating heart muscle cells.
research In Vitro and In Vivo Models for the Development of Hair Growth Materials By Regulating the β-Catenin Signaling Pathways
The research found a way to develop hair growth materials by targeting a specific signaling pathway.
research Skin toxicity determined in vitro by three-dimensional, native-state histoculture.
This model can replace animal testing for quick, cost-effective skin toxicity tests.
research Saccharomyces cerevisiae BLYAS, a New Bioluminescent Bioreporter for Detection of Androgenic Compounds
The engineered yeast strain BLYAS can quickly and sensitively detect androgenic chemicals.
research High-throughput and direct measurement of androgen levels using turbulent flow chromatography liquid chromatography-triple quadrupole mass spectrometry (TFC-LC-TQMS) to discover chemicals that modulate dihydrotestosterone production in human prostate cancer cells
Researchers found four natural compounds that can change DHT levels in prostate cancer cells.
research 895 Isoproterenol directs human hair follicle-associated pluripotent (hHAP) stem cells to differentiate to cardiac muscle cells
Human hair follicles can be used to create heart muscle cells.
research Further Immunocytochemical Characterization of Cultured Hair Apparatus Cells
Immature hair cells can grow and change into different types of hair cells over time.
research LC-APCI+-MS/MS method for the analysis of ten hormones and two endocannabinoids in plasma and hair from the mice with different gut microbiota
The method accurately measures hormones and endocannabinoids in mice, showing gut microbiota diversity affects these levels and may influence stress and reproductive systems.
research Camellia japonica seed extract promotes hair growth by preventing dermal papilla cell senescence and activating hair follicle stem cells
Camellia japonica seed extract helps hair grow by activating hair follicles and preventing cell aging.
research Noninvasive method for assessing the human circadian clock using hair follicle cells
Scientists found a new, less invasive way to study body clocks using hair cells, which shows shift workers' body clocks don't match their lifestyles.
research Simultaneous Analysis of Biomarkers in Human Hair for Evaluating Chronic Tobacco Smoke Exposure and Stress/Relaxation Using Online In-Tube Solid-Phase Microextraction Coupled with Liquid Chromatography–Tandem Mass Spectrometry
A new method can quickly and accurately measure tobacco exposure and stress using a small hair sample.
research Assessment of the anti‐hair loss potential of Camellia japonica fruit shell extract in vitro
Camellia japonica fruit shell extract may help reduce hair loss by promoting hair cell growth and reducing stress effects.
research Measurement of steroid hormones by liquid chromatography-tandem mass spectrometry with small amounts of hair
A new method accurately measures steroid hormones in a few hair strands and could help study chronic stress and hair loss.
research New Insight Into the Immunostaining Method Suitable for the Pilosebaceous Complex Unit
The study found that a one-step antibody method is better than the LSAB method for accurately studying hair follicle structures without false positives.
research Cell observation method under near-living conditions by scanning electron microscopy
The method using ionic liquid improves observation of cell structures with less damage.
research Long-term live imaging, cell identification and cell tracking in regenerating crustacean legs
A new method allows detailed tracking of cell regeneration in crustacean legs.
research A technique for more precise distinction between catagen and telogen human hair follicles ex vivo
Researchers developed a new method using methylene blue staining to more accurately identify the growth stage of human hair follicles.
research A review for cell-based screening methods in drug discovery
Cell-based screening methods are useful and cost-effective for drug discovery but have pros and cons.
research A Fast and Efficient UPLC-ESI-MS/MS Method for Detection, Identification, and Quantitative Analysis of Bioactive Substances in Medicinal Herbal Extracts of Preventing Hair Loss
Researchers developed a quick and sensitive method to identify and measure hair growth-promoting substances in a herbal mix.
research Novel Application of Layered Expression Scanning for Proteomic Profiling of Plucked Hair Follicles
A new method for studying hair follicles is easier and more precise, useful for hair loss and cancer treatment research.
research A liquid chromatography/tandem mass spectrometry method for determination of aristolochic acid‐I in rat plasma
A reliable method was developed to measure aristolochic acid-I in rat blood.