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Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

Sox6 is important in heart and kidney health, affecting diseases like diabetes, heart disease, and high blood pressure.

YAP and TAZ proteins control skin cell growth and repair.

Keratin mutations may cause scarring alopecia by damaging hair structure.

Vitamin A is important for healthy skin and hair, influencing hair growth and skin healing, but UV light reduces its levels.

Lindera aggregata has many beneficial compounds that can help prevent and manage diseases.

Reducing reactive oxygen species can help treat nerve damage from platinum cancer drugs.

The link between anabolic agents and colorectal cancer risk is unclear.

The genes KRT25 and SP6 affect curly hair in horses, with KRT25 also causing hair loss. If both genes are mutated, the horse gets curly hair and hair loss. KRT25 can hide the effect of SP6.

Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.

Stem cells slowed lung tumor growth but increased colon tumor growth in mice.

Syntaxin 9 helps in transporting and signaling of the EGF receptor in skin and stomach cells.

Neuroregulation is crucial for skin wound healing and can be targeted to improve recovery.

Early detection of specific VDR mutations is crucial for effective treatment and better dental outcomes in children with hereditary vitamin D–resistant rickets.

PPAR β/δ is important for skin health and disease treatment, but more research is needed.

Injectable biomimetic gels can help heal tissues and deliver drugs but need improvements in strength and delivery.

Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.

Different sPLA2 enzymes have unique roles in phospholipid metabolism and biological processes.

Iron is crucial for skin health, with specific proteins recycling it to support skin functions and prevent its release.

Hairless protein and putrescine regulate each other, affecting hair growth and skin balance.

More research is needed to improve wool and cashmere quality through genetics.

Significant progress was made in understanding androgen excess disorders, but much is still unknown.

Dexpanthenol helps protect the heart from damage by reducing inflammation and stress.

Three new gene mutations cause rickets and hair loss, treatable with high calcium and calcidol, but hair regrowth is rare.

Blocking the mineralocorticoid receptor improves wound healing by reducing inflammation and promoting blood vessel growth.

Overexpressing CtBP1 in skin cells causes skin and hair problems.

In 2024, the FDA approved 27 innovative small-molecule drugs, with many offering significant treatment improvements.

IGF2BP3 and other m6A-related genes are linked to keloid formation and could be potential treatment targets.

The research improved understanding of yak hair growth to help use yak wool better.