55 citations
,
February 2014 in “Journal of Structural Biology” Human hair has a complex, variable structure with a consistent matrix and double-twist pattern.
November 2025 in “Journal of the European Academy of Dermatology and Venereology” Different types of hidradenitis suppurativa need specific treatments based on unique skin cell issues.
159 citations
,
October 1986 in “The Histochemical Journal”
14 citations
,
November 2013 in “PloS one” HGF/SF increases skin melanocytes but doesn't change melanin type or amount.
June 2003 in “Obstetrical & Gynecological Survey” Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.
August 2023 in “Journal of analytical & pharmaceutical research” Microneedle-assisted therapy with human basic fibroblast growth factor significantly regrew hair in patients with hair loss.
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Changing the structure of the hair follicle's environment can affect hair quality but doesn't stop hair growth.
January 2009 in “China Practical Medicine” Certain genes help dermal papillae cells in hair follicles grow and group together.
2 citations
,
December 2024 in “International Journal of Molecular Sciences” Liver stem cells keep their basic functions even in inflamed liver tissue.
125 citations
,
February 2007 in “The EMBO Journal” Fgfr2b helps maintain healthy skin and prevent cancer.
CRISPR gene editing reduces harmful molecules in cells from Emery–Dreifuss Muscular Dystrophy patients.
October 1995 in “Pediatric Research”
8 citations
,
October 2016 in “Experimental dermatology” Hair follicles may help teach the immune system to tolerate new self-antigens, but this can sometimes cause hair loss.
14 citations
,
June 2017 in “Immunity” Special immune cells called Treg cells are important for maintaining and regenerating hair by activating a specific growth signal in hair stem cells.
254 citations
,
January 2012 in “Nature Reviews Molecular Cell Biology” Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
2 citations
,
July 2024 in “Materials Today Communications” The FN3-Alg hydrogel effectively heals irregular wounds and promotes hair growth.
14 citations
,
April 2011 in “Cell Proliferation” Scientists can grow human hair follicle stem cells in a lab without changing their nature, which could help treat hair loss.
January 2016 in “Memorial University Research Repository (Memorial University)” Hereditary hyperplastic gingivitis in silver foxes may be linked to errors in the MAPK signaling pathway, influenced by androgens.
1 citations
,
April 2018 in “Journal of Investigative Dermatology” Lower proximal cup cells, not bulge stem cells, regenerate hair follicles after chemotherapy.
1 citations
,
September 2025 in “International Journal of Molecular Sciences” Cells from concentrated growth factor can become different cell types.
April 2023 in “Journal of Investigative Dermatology” Type 2 inflammation helps wound healing by switching immune cells to repair mode.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” The study found markers indicating that cells responsible for hair color are differentiating in specific areas of the hair follicle.
4 citations
,
January 2016 in “Methods in molecular biology” Hair follicle stem cells can become nerve cells using specific treatments.
33 citations
,
September 2008 in “Biochemical and Biophysical Research Communications” Hair follicles can be used to easily create neurons and glial cells for potential nerve repair.
January 2006 in “Chinese Journal of Dermatology” Mesenchymal cells are essential for hair follicle stem cell growth.
OCT4B1 and SOX-2 levels are higher in Crohn's and ulcerative colitis patients, possibly aiding tissue repair.
5 citations
,
September 2011 in “Cell stem cell” Epigenetic changes are crucial for hair follicle stem cells to function properly.
3 citations
,
July 2023 in “Frontiers in Aging” Hair follicle stem cells change states with age, affecting hair growth and aging.
13 citations
,
March 2020 in “Genes” Disrupting the FGF5 gene in rabbits leads to longer hair by extending the hair growth phase.
The 1550 nm fractional Er:Glass laser improved hair regrowth in patients with androgenic alopecia, but didn't significantly change collagen type I, skin fibroblasts, or macrophages. More research is needed for optimal results.