research Studies on changes in the concentration of serum adrenal androgens in pubertal twins
Adrenal androgens are important for puberty and are influenced by genetics.
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research PSAT097 Patient Preference Research: Preferred Adjunctive Medication Attributes of Adult Patients with Classic Congenital Adrenal Hyperplasia
Adults with classic congenital adrenal hyperplasia value medication that prevents weight gain from glucocorticoids the most.
research The Effect of Drugs on Hair
Drugs can change hair growth and this is important because it can upset people.
research SERUM-CONCENTRATIONS OF Dehydroepyandrosterone-sulfate IN MEN WITH ANDROGENETIC ALOPECIA
Men with hair loss don't necessarily have higher levels of the hormone DHEA-S, but this hormone tends to decrease with age.
research Restricted effects of androgens on glucocorticoid signaling in the mouse prefrontal cortex and midbrain
Androgens can affect glucocorticoid signaling in specific mouse brain areas.
research The human hair follicle has established a fully functional peripheral equivalent of the hypothamalic‐pituitary‐adrenal‐axis (HPA)
Human hair follicles can produce stress hormones like the body's main stress response system.
research SAT0631-HPR WHEN CAN I STOP MY STEROIDS? THE PATIENT PERSPECTIVE ON GLUCOCORTICOID USAGE IN ADULT INFLAMMATORY MYOPATHY
Patients need better information about the risks of long-term steroid use.
research Functions of peroxisome proliferator‐activated receptors (PPAR) in skin homeostasis
PPARs help regulate skin health and could be used to treat skin disorders.
research Estrogen and androgen signaling in the pathogenesis of BPH
Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.
research Influence of glucocorticoids on a time-of-day-dependent variation in intradermal reactivity to histamine in dogs
Glucocorticoids affect dogs' skin reactions to histamine, which vary by time of day.
research A Convenient Synthesis of (16S,20S)-3β-Hydroxy-5α-pregnane-20,16-carbolactam and Its N-alkyl Derivatives
A new, efficient method was developed to synthesize a specific compound and its derivatives.
research Lack of androgen receptor transcriptional activity in human keratinocytes
Human keratinocytes do not naturally respond to androgens.
research A case report of a novel homozygote mutation causing severe Leydig cell hypoplasia: insights in the coexistence of nonsense mutation and polymorphism in the same LHCGR gene locus
A new genetic mutation causes severe Leydig cell hypoplasia, affecting sexual development.
research Clinical analysis of 78 patients with non-classical 21-hydroxylase deficiency
Low-dose glucocorticoid treatment improves pregnancy and birth rates in women with nonclassical 21-hydroxylase deficiency.
research Estimation of Dehydroepiandrosterone (DHEA) and Tumor Necrosis Factor–Alpha (TNF-α) Levels Women Diagnosed with Polycystic Syndrome
Women with PCOS have higher levels of DHEA, IL-6, and TNF-α.
research Machine learning-based steroid metabolome analysis reveals three distinct subtypes of polycystic ovary syndrome and implicates 11-oxygenated androgens as major drivers of metabolic risk
PCOS has three subtypes, with 11-oxygenated androgens increasing metabolic risk.
research Steroid Sulfatase in the Human Hair Follicle Concentrates in the Dermal Papilla
Steroid sulfatase in hair follicles may be a target for treating hair loss.
research Role of Dehydroepiandrosterone (DHEA) in the Pathophysiology and Clinical Manifestations of Polycystic Ovary Syndrome (PCOS)
DHEA may play a complex role in PCOS, affecting hormones, metabolism, and symptoms.
research A new method for synthesis of finasteride
A new, safer method to make finasteride from progesterone is effective for industrial use.
research The role of androgens in hormone replacement therapy
Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.
research Hyperandrogenism: Acne and Hirsutism
Personalized treatment is crucial for women with hyperandrogenism-related acne and hirsutism.
research The effects of benzodiazepines on hormones in women with idiopathic hirsutism
Benzodiazepines changed hormone levels but did not affect hair growth in women with idiopathic hirsutism.
research The Evaluation and Treatment of Hirsute Women
Excessive body hair in women can be caused by various conditions and treated with medication like Diane® 35 or androgen blockers.
research Testosterone, 17 Ks, 17 beta E2 FSH-LH variations and hirsutism modifications during spironolactone therapy.
Spironolactone treatment reduced hair growth and androgen levels in hirsute women, but the overall effectiveness was just adequate.
research 5α-reductase inhibitors
5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.
research Effects of androgen overproduction on skin target organs in children with congenital adrenal hyperplasia
research Testosterone replacement in the setting of Finasteride therapy: a therapeutic dilemma
research REAL WORLD STUDY ON ORAL ESTRADIOL TREATMENT IN TRANSGENDER WOMEN
GnRH-a or orchiectomy is more effective than anti-androgens for managing hormone levels in transgender women.
research Androstenedione
Androstenedione, a hormone supplement, doesn't improve muscle or performance and can cause harmful side effects.
research Central 5-alpha reduction of testosterone is required for testosterone's inhibition of the hypothalamo-pituitary–adrenal axis response to restraint stress in adult male rats
Testosterone needs to be converted to DHT to reduce stress response in male rats.