28 citations
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September 1995 in “Biochemistry and Cell Biology” Merkel cells are more densely found in hairless skin areas like palms and soles.
April 2026 in “Research Square” January 1990 in “The Nishinihon Journal of Dermatology” Follicular structures help differentiate keratoacanthoma from squamous cell carcinoma.
33 citations
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September 2017 in “Journal of Investigative Dermatology” A mutation in the KRT25 gene causes woolly hair and hair loss.
181 citations
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January 2009 in “Nature Genetics” Certain mutations in a hair growth-related gene cause a type of genetic hair loss.
72 citations
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November 2017 in “Journal of developmental biology” The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.
6 citations
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October 2022 in “Journal of cell science” Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.
387 citations
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November 2003 in “Journal of Investigative Dermatology” The K15 promoter effectively targets stem cells in the hair follicle bulge.
January 2016 in “Frontiers in Bioengineering and Biotechnology” Keratin-based hydrogels can be improved for medical use by adding PEG, making them more soluble and adjustable.
38 citations
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November 2020 in “International journal of biochemistry & cell biology” Keratin proteins are essential for keeping the cells in the human colon healthy and stable.
15 citations
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December 2014 in “PLoS ONE” A mutation in the iRhom2 gene causes hairless mice due to abnormal hair follicle development.
22 citations
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September 2000 in “Journal of Investigative Dermatology” μ-Crystallin may help hair growth by affecting thyroid hormone levels in mouse hair follicles.
18 citations
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June 2001 in “Journal of Investigative Dermatology” Adding a specific gene to skin cells can help treat skin disorders like psoriasis.
26 citations
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July 1993 in “Journal of Investigative Dermatology”
54 citations
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January 2013 in “Journal of Biological Macromolecules” A new method effectively separates keratin-associated proteins and keratin from human hair.
9 citations
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February 1984 in “Zentralblatt für Veterinärmedizin Reihe A” Biotin is essential for healthy skin and claws in pigs.
7 citations
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January 1998 in “EXPERIMENTAL ANIMALS” The skin of both rat strains showed similar lectin binding patterns.
3 citations
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June 2017 in “Journal of Biomaterials Applications” Keratin extract from human hair was found to promote hair growth in mice.
The research developed a human hair keratin and silver ion hydrogel that could help heal wounds.
September 2004 in “Experimental Dermatology” Key signals like Wnt and β-catenin are crucial for skin and hair development, with potential for treating skin disorders.
1 citations
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April 2008 in “Experimental Dermatology” Hidradenitis suppurativa may mainly affect vellus hair follicles, not terminal ones.
January 2024 in “Journal of cellular immunology” Hair follicle stem cells are important for maintaining healthy skin and interact with many signals.
90 citations
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August 2004 in “Physiological Genomics” Dermal papilla cells help skin stem cells grow into hair.
1 citations
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January 2006 in “Clínicas obstétricas y ginecológicas de Norteamérica” Analyzing hair proteins can help identify new markers for hair health and aging.
26 citations
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May 2014 in “BioEssays” Using neurohormones to control keratin can lead to new skin disease treatments.
2 citations
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January 1975 in “Archives of Dermatological Research” Certain enzymes react strongly with some hormones in rat skin during hair growth, mainly in sebaceous glands and hair sheaths.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” The hexosamine pathway helps maintain healthy skin by affecting the skin's structure and possibly increasing hair follicle stem cells.
November 2022 in “Journal of Investigative Dermatology” ILC1-like cells can cause alopecia areata by themselves.
21 citations
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December 2015 in “European journal of cell biology” Tight junctions create a barrier in pig hair follicles that controls what can enter the skin.
14 citations
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July 2010 in “Experimental Dermatology” A new mutation in the HR gene causes hair loss in a specific family.