research Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance
Repurposing existing drugs and using micronutrients may effectively target cancer stem cells and improve cancer treatment.
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360-390 / 770 resultsresearch Medicinal Chemistry of Drugs with N-Oxide Functionalities
N-oxides are important in medicine for improving drug properties and targeting.
research Testosterone Prevents Cutaneous Ischemia and Necrosis in Males Through Complementary Estrogenic and Androgenic Actions
Testosterone helps prevent skin damage in males by acting through both estrogen and androgen pathways.
research β-sitosterol in Yijing Hugui decoction prevents cyclophosphamide-induced premature ovarian insufficiency via the AKT1/Nrf2 pathway
research The Therapeutic Role of ADSC-EVs in Skin Regeneration
ADSC-derived extracellular vesicles show promise for skin and hair regeneration and wound healing.
research Mechanisms of autophagy and their implications in dermatological disorders
Targeting autophagy can help treat skin disorders like vitiligo and atopic dermatitis.
research Lupeol: an updated review utilizing AI-assisted predictive tools for enhanced therapeutic insights into lupeol’s potential for alopecia management
Lupeol shows promise for hair growth but needs better absorption and safety testing.
research Promising improvement in infected Wound Healing in Type two Diabetic rats by Combined effects of conditioned medium of human adipose-derived stem cells plus Photobiomodulation
Combining stem cell medium and light therapy improves wound healing in diabetic rats.
research Chemistry, Pharmacology and Therapeutic Potential of Decursin: A Promising Natural Lead for New Drug Discovery and Development
Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.
research Resolution of experimental malaria-associated acute respiratory distress syndrome is Alox12 independent and shows residual inflammation
Resolving malaria-related lung issues doesn't rely on Alox12 and leaves some inflammation.
research Secretome of Hypoxic Mesenchymal Stem Cells Improves Fluconazole-Induced Alopecia in Rats via Immunoregulatory Modulation of IL-15 and IFN-γ
A gel from stem cells can reduce baldness caused by fluconazole in rats.
research Calcium channel inhibitor and extracellular calcium improve aminoglycoside-induced hair cell loss in zebrafish
Certain substances can protect against ear damage from some antibiotics in zebrafish.
research Iron–Skin Axis: Exploring the Interplay between Iron Homeostasis and Skin Disorders
Iron balance is crucial for skin health, affecting conditions like psoriasis and hair loss.
research Wound healing: cellular mechanisms and pathological outcomes
Better understanding of wound healing is needed to develop effective treatments for chronic wounds.
research Progenitor Cell Dysfunctions Underlie Some Diabetic Complications
Diabetes causes lasting cell dysfunctions, leading to serious complications even after blood sugar is controlled.
research Effects of microenvironment and biological behavior on the paracrine function of stem cells
Mesenchymal stem cells release substances that help tissue repair, and their effectiveness can be improved by understanding environmental influences.
research Exploring nanobioceramics in wound healing as effective and economical alternatives
Nanobioceramics can effectively and cheaply heal wounds without side effects.
research Exogeneous metal ions as therapeutic agents in cardiovascular disease and their delivery strategies
Metal ions can help treat heart diseases by protecting cells and repairing tissues.
research What does the research say about androgen use and cerebrovascular events?
Androgen use may increase the risk of stroke, but more research is needed.
research The Role of Natural Hydrogels in Enhancing Wound Healing: From Biomaterials to Bioactive Therapies
Natural hydrogels can improve wound healing but face challenges in becoming widely used in clinics.
research Forensic approach in cases of anabolic-androgenic steroid abuse and cardiovascular mortality: insights from autopsy, histopathology, immunohistochemistry and toxicology
Anabolic-androgenic steroid abuse can cause heart damage and sudden death.
research Toward a Unifying Hypothesis for Redesigned Lipid Catabolism as a Clinical Target in Advanced, Treatment-Resistant Carcinomas
Targeting lipid metabolism can help treat advanced, resistant cancers.
research Brown adipose tissue in the form of innovative approach for polycystic ovary syndrome treatmentstill long time to reach clinical arena: a narrative review
Brown Adipose Tissue (BAT) could potentially treat Polycystic Ovary Syndrome (PCOS) by controlling energy balance and lipid homeostasis, but more human research is needed.
research Overview of the Circadian Clock in the Hair Follicle Cycle
The circadian clock plays a key role in hair growth and its disruption can affect hair regeneration.
research Mineral Deficiencies: A Root Cause for Reduced Longevity in Mammals
Not getting enough minerals can lead to health problems and shorter lifespans.
research Research progress on the natural products in the intervention of myocardial infarction
Natural products may be safer and effective alternatives for managing heart attacks.
research Whole-genome resequencing to investigate the genetic diversity and the molecular basis underlying key economic traits in indigenous sheep breeds adapted to hypoxic environments
Tibetan sheep have specific genes for high-altitude adaptation and wool traits, aiding breeding strategies.
research Proteomic Analysis of Two Stem Cell Secretomes Used in Combination in a Topical Skin Care Product That Has Demonstrated Efficacy in a Double-Blinded, Vehicle-Controlled Clinical Trial
The combined stem cell secretome in the skin care product effectively reduces inflammation and promotes tissue regeneration.
research Cellular therapeutics and immunotherapies in wound healing – on the pulse of time?
Cellular and immunotherapies show promise for healing chronic wounds but need more research.
research Extracellular vesicles from hair follicle-derived mesenchymal stromal cells: isolation, characterization and therapeutic potential for chronic wound healing
Hair follicle-derived extracellular vesicles may help heal chronic wounds as effectively as those from adipose tissue.